Granulins rescue inflammation, lysosome dysfunction, lipofuscin, and neuropathology in a mouse model of progranulin deficiency
在小鼠前粒蛋白缺乏症模型中，粒蛋白能够挽救炎症、溶酶体功能障碍、脂褐素沉积和神经病理学改变。
期刊:Cell Reports
影响因子:7.5
doi:10.1016/j.celrep.2024.114985
Jessica Root ,Anarmaa Mendsaikhan ,Georgia Taylor ,Paola Merino ,Srijita Nandy ,Minzheng Wang ,Ludmilla Troiano Araujo ,Danny Ryu ,Christopher Holler ,Bonne M Thompson ,Giuseppe Astarita ,Jean-François Blain ,Thomas Kukar
