日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Targeting ENO1 reprograms macrophage polarization to trigger antitumor immunity and improves the therapeutic effect of radiotherapy.

靶向 ENO1 可重编程巨噬细胞极化，从而触发抗肿瘤免疫，并提高放射疗法的治疗效果。

期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-026-08416-7
Lin Yu-Sen, Chang Hsin-Yu, Hong Wei-Ze, Chen Jhen-Yu, Huang Wei-Ching, Yuan Ta-Tung, Ke Tao-Wei, Tsai Yuan-Yao, Chen Te-Hong, Liang Ji-An, Chao Jui-I, Chao K S Clifford, Huang Kevin Chih-Yang
细胞生物学
巨噬细胞
肿瘤免疫
巨噬细胞
发表日期：2026
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Loss of MicroRNA-29b promotes DNMT3b-mediated STING downregulation to attenuate radiotherapy-induced antitumor immunity in KRAS-mutated colorectal cancer.

MicroRNA-29b 的缺失促进 DNMT3b 介导的 STING 下调，从而减弱 KRAS 突变型结直肠癌中放射治疗诱导的抗肿瘤免疫。

期刊:npj Precision Oncology
影响因子:8
doi:10.1038/s41698-026-01290-8
Chang Hsin-Yu, Chen Jhen-Yu, Ke Tao-Wei, Jiang Yi-Wen, Hong Wei-Ze, Tsai Yuan-Yao, Chiang Shu-Fen, Lin Yu-Sen, Huang Chi-Hsien, Chen Te-Hong, Chao K S Clifford, Huang Kevin Chih-Yang
肿瘤
肠癌
肿瘤免疫
STING
RAS
免疫/内分泌
发表日期：2026
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Heterologous prime-boost immunization of AAV-based neoantigen cancer vaccine induces anti-tumor immunity to inhibit tumor growth and relapse.

基于 AAV 的新抗原癌症疫苗的异源初免-加强免疫可诱导抗肿瘤免疫，从而抑制肿瘤生长和复发。

期刊:Cancer Immunology Immunotherapy
影响因子:5.1
doi:10.1007/s00262-026-04336-9
Huang Chi-Hsien, Chen Jhen-Yu, Chang Hsin-Yu, Hong Wei-Ze, Jiang Yi-Wen, Lee Chien-Yueh, Wu Chia-Hsin, Lin Yu-Sen, Tsai Yuan-Yao, Kao Wei-Ling, Chao K S Clifford, Huang Kevin Chih-Yang
免疫/内分泌
肿瘤免疫
发表日期：2026
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CHK1 inhibition increases the therapeutic response to radiotherapy via antitumor immunity in ARID1A-deficient colorectal cancer.

CHK1 抑制通过 ARID1A 缺陷型结直肠癌的抗肿瘤免疫增强放射治疗的疗效

期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-025-07912-6
Chen Jhen-Yu, Ke Tao-Wei, Chiang Shu-Fen, Hong Wei-Ze, Chang Hsin-Yu, Liang Ji-An, Tsai Yuan-Yao, Huang Chi-Hsien, Chen William Tzu-Liang, Chao K S Clifford, Huang Kevin Chih-Yang
肿瘤
肿瘤免疫
发表日期：2025
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Strategic Design of Biocompatible, Glistening-Free, and Foldable Artificial Intraocular Lenses Based on Hydro-Amphiphilic Ternary Copolymers

基于水-两亲性三元共聚物的生物相容性、无光泽、可折叠人工晶状体的战略设计

期刊:Biomacromolecules
影响因子:5.4
doi:10.1021/acs.biomac.5c00588
Hu, Cheng-Ti; Liang, Zhi-Xuan; Luo, Jhen-Yu; Chiu, Po-Hsun; Day, Annabelle I; Hsieh, Chih-Chen; Shih, Po-Jen; Li, Jia-Han; Kuo, Bo-I; Wang, I-Jong; Yen, Jia-Yush; Dai, Chi-An
发表日期：2025
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RETRACTED: Huang et al. Adenine Combined with Cisplatin Promotes Anticancer Activity Against Hepatocellular Cancer Cells Through AMPK-Mediated p53/p21 and p38 MAPK Cascades. Pharmaceuticals 2022, 15, 795

撤稿：Huang 等人，《腺嘌呤联合顺铂通过 AMPK 介导的 p53/p21 和 p38 MAPK 级联反应促进抗肝细胞癌活性》，Pharmaceuticals 2022, 15, 795

期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph18020263
Huang, Jhen-Yu; Lin, You-Cian; Chen, Han-Min; Lin, Jiun-Tsai; Kao, Shao-Hsuan
AMPK
p38 MAPK
发表日期：2025
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Colorectal cancer-specific IFNβ delivery overcomes dysfunctional dsRNA-mediated type I interferon signaling to increase the abscopal effect of radiotherapy

结肠直肠癌特异性 IFNβ 输送可克服功能失调的 dsRNA 介导的 I 型干扰素信号传导，从而增强放射治疗的远隔效应

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.3
doi:10.1136/jitc-2023-008515
Kevin Chih-Yang Huang #, Shu-Fen Chiang, Hsin-Yu Chang, Wei-Ze Hong, Jhen-Yu Chen, Pei-Chih Lee, Ji-An Liang, Tao-Wei Ke, Shin-Lei Peng, An-Cheng Shiau, Tsung-Wei Chen, Pei-Chen Yang, William Tzu-Liang Chen, K S Clifford Chao #
信号转导
肿瘤
肠癌
FCM
IF
IHC-P
WB
STAT1
发表日期：2024
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Activation of STING by the novel liposomal TLC388 enhances the therapeutic response to anti-PD-1 antibodies in combination with radiotherapy

新型脂质体 TLC388 激活 STING 可增强抗 PD-1 抗体与放射疗法联合治疗的治疗效果

期刊:Cancer Immunology Immunotherapy
影响因子:8.1
doi:10.1007/s00262-024-03692-8
Jhen-Yu Chen, Po-Yu Lin, Wei-Ze Hong, Pei-Chen Yang, Shu-Fen Chiang, Hsin-Yu Chang, Tao-Wei Ke, Ji-An Liang, William Tzu-Liang Chen, K S Clifford Chao, Kevin Chih-Yang Huang
信号转导
发表日期：2024
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Challenges for Medical Students in Applying Ethical Principles to Allocate Life-Saving Medical Devices During the COVID-19 Pandemic: Content Analysis

新冠疫情期间医学生在应用伦理原则分配救生医疗器械方面面临的挑战：内容分析

期刊:
影响因子:
doi:10.2196/52711
Hsieh, Hsing-Yen; Lin, Chyi-Her; Huang, Ruyi; Lin, Guan-Chun; Lin, Jhen-Yu; Aldana, Clydie
微生物学
新冠
发表日期：2024
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Rosmarinic Acid Potentiates Cytotoxicity of Cisplatin against Colorectal Cancer Cells by Enhancing Apoptotic and Ferroptosis

迷迭香酸通过增强细胞凋亡和铁凋亡增强顺铂对结直肠癌细胞的细胞毒性

期刊:Life-Basel
影响因子:
doi:10.3390/life14081017
Jhen-Yu Huang, Ta-Wen Hsu, Yu-Ru Chen, Shao-Hsuan Kao
信号转导
细胞生物学
肿瘤
肠癌
肿瘤细胞
FCM
IF
IHC-P
Apoptosis
ACTC
发表日期：2024
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