日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Strawberry Notch 1 Acts as a Transcriptional Regulator Driving Oncogenic Programs in Liver Carcinogenesis

草莓Notch 1作为转录调控因子，驱动肝癌发生过程中的致癌程序。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202507238
Fritzsche, Sarah; Sugiyanto, Raisatun Nisa; Gür, Kira; Krumme, Alina; Marois, Maxime Le; Fraas, Angelika; Inal, Aslihan; Huerta, Mario; Henriques, Vanessa; Eiteneuer, Eva; Albrecht, Thomas; Charbel, Alphonse; Dill, Michael T; Sticht, Carsten; De La Torre, Carolina; Pusch, Stefan; Mehrabi, Arianeb; Breuhahn, Kai; Ji, Junfang; Schirmacher, Peter; Goeppert, Benjamin; Roessler, Stephanie
肿瘤
表观遗传
肿瘤免疫
Notch
信号转导
肝癌
转录调控
发表日期：2026
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CircRSU1 Activates the hnRNPA1/HIF-1α/CD24 Signaling Axis, Promoting Stemness Features of Hepatocellular Carcinoma.

CircRSU1 激活 hnRNPA1/HIF-1α/CD24 信号轴，促进肝细胞癌的干细胞特性。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202522424
Xue Shuting, Wei Danduo, Zhao Yongzhi, Pan Jinchang, Zhang Hanyuan, Liu Niya, Zhang Jianjuan, Liu Jiaxin, Jin Jianping, Xiao Mu, Feng Xinhua, Lin Aifu, Zhao Lei, Roessler Stephanie, Ji Junfang
肿瘤
发育与干细胞
肿瘤免疫
信号转导
CD24
干细胞
细胞生物学
CD2
发表日期：2026
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A new inject-embed 3D culture method enables the spheroid and aggregate formation from single or dual liver cancer cell types.

一种新的注射-包埋 3D 培养方法能够从单一或两种肝癌细胞类型中形成球状体和聚集体。

期刊:Cancer Cell International
影响因子:6
doi:10.1186/s12935-026-04250-1
Zhang Hanyuan, Xue Shuting, Pan Jinchang, Zhang Jianjuan, Wei Danduo, Xia Peng, Li Guangming, Roessler Stephanie, Yu Chaohui, Ji Junfang
肿瘤
肿瘤免疫
肝癌
3D/类器官
细胞生物学
发表日期：2026
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The Ubiquitin Ligase Zinc Finger SWIM Domain-Containing Protein 8 Regulates Oligodendrocyte Development Through the Argonaute2/MicroRNA-7 Axis

泛素连接酶锌指SWIM结构域蛋白8通过Argonaute2/MicroRNA-7轴调控少突胶质细胞发育

期刊:Glia
影响因子:5.1
doi:10.1002/glia.70142
Lei, Jing; Zhong, Siming; Fan, Rong; Shu, Xin; Wang, Guan; Guo, Jiansheng; Xue, Shuting; Zheng, Luqian; Ren, Aiming; Ji, Junfang; Yang, Bing; Duan, Shumin; Wang, Zhiping; Guo, Xing
胶质细胞
信号转导
细胞生物学
发育与干细胞
发表日期：2026
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DNA methylation patterns facilitate tracing the origin of neuroendocrine neoplasms

DNA甲基化模式有助于追踪神经内分泌肿瘤的起源

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-65227-8
Goeppert, Benjamin; Charbel, Alphonse; Toth, Reka; Zhang, Yue; Tabbakh, Danial; Albrecht, Thomas; Schrimpf, Daniel; de Mestier, Louis; Cros, Jérôme; Vogel, Monika Nadja; Chang, De-Hua; Bohn, Eva-Marie; Brobeil, Alexander; Ji, Junfang; Singer, Stephan; Nazarov, Petr V; Perren, Aurel; Apostolidis, Leonidas; von Deimling, Andreas; Roessler, Stephanie
肿瘤
表观遗传
肿瘤免疫
DNA甲基化
发表日期：2025
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Proteomic profiling reveals CEACAM6 function in driving gallbladder cancer aggressiveness through integrin receptor, PRKCD and AKT/ERK signaling

蛋白质组学分析揭示CEACAM6通过整合素受体、PRKCD和AKT/ERK信号通路驱动胆囊癌侵袭性的功能

期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-024-07171-x
Sugiyanto, Raisatun Nisa; Metzger, Carmen; Inal, Aslihan; Truckenmueller, Felicia; Gür, Kira; Eiteneuer, Eva; Huth, Thorben; Fraas, Angelika; Heinze, Ivonne; Kirkpatrick, Joanna; Sticht, Carsten; Albrecht, Thomas; Goeppert, Benjamin; Poth, Tanja; Pusch, Stefan; Mehrabi, Arianeb; Schirmacher, Peter; Ji, Junfang; Ori, Alessandro; Roessler, Stephanie
肿瘤
肿瘤免疫
信号转导
MAPK/ERK
CEACAM6
胆囊癌
AKT
发表日期：2024
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WDR20 prevents hepatocellular carcinoma senescence by orchestrating the simultaneous USP12/46-mediated deubiquitination of c-Myc.

WDR20 通过协调 USP12/46 介导的 c-Myc 去泛素化来阻止肝细胞癌衰老

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2407904121
Jiang Li, Qi Xuxin, Lai Minshan, Zhou Jiahao, Yuan Meng, You Jieqiong, Liu Qiang, Pan Jinchang, Zhao Luyao, Ying Meidan, Ji Junfang, Li Ke, Zhang Yan, Pan Weiwei, He Qiaojun, Yang Bo, Cao Ji
细胞生物学
SP1
泛素化
发表日期：2024
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The HRD1-SEL1L ubiquitin ligase regulates stress granule homeostasis in couple with distinctive signaling branches of ER stress

HRD1-SEL1L 泛素连接酶与内质网应激的独特信号传导分支一起调节应激颗粒稳态

期刊:iScience
影响因子:4.6
doi:10.1016/j.isci.2024.110196
Wenbo Shi, Ran Ding, Yilin Chen, Fubo Ji, Junfang Ji, Weirui Ma, Jianping Jin
信号转导
IHC
IP
WB
Goat
VCP
发表日期：2024
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Liver cancer heterogeneity modeled by in situ genome editing of hepatocytes

利用肝细胞原位基因组编辑模拟肝癌异质性

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.abn5683
Tang, Mei; Zhao, Yang; Zhao, Jianhui; Wei, Shumei; Liu, Mingwei; Zheng, Nairen; Geng, Didi; Han, Shixun; Zhang, Yuchao; Zhong, Guoxuan; Li, Shuaifeng; Zhang, Xiuming; Wang, Chenliang; Yan, Huan; Cao, Xiaolei; Li, Li; Bai, Xueli; Ji, Junfang; Feng, Xin-Hua; Qin, Jun; Liang, Tingbo; Zhao, Bin
细胞生物学
肿瘤
肝癌
肿瘤免疫
发表日期：2022
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MiR-125b Loss Activated HIF1α/pAKT Loop, Leading to Transarterial Chemoembolization Resistance in Hepatocellular Carcinoma

miR-125b缺失激活HIF1α/pAKT环路，导致肝细胞癌经动脉化疗栓塞治疗耐药

期刊:Hepatology
影响因子:15.8
doi:10.1002/hep.31448
Wei, Xiyang; Zhao, Lei; Ren, Ruizhe; Ji, Fubo; Xue, Shuting; Zhang, Jianjuan; Liu, Zhaogang; Ma, Zhao; Wang, Xin W; Wong, Linda; Liu, Niya; Shi, Jiong; Guo, Xing; Roessler, Stephanie; Zheng, Xin; Ji, Junfang
肿瘤
肿瘤免疫
治疗耐药
细胞生物学
AKT
发表日期：2021
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