日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Replication-Competent, Tumor-Specific Immuno-Gene Vectors Allow for Exchange of Transgenes and Lead to Viral Persistence Following IV Administration

具有复制能力的肿瘤特异性免疫基因载体允许转基因交换,并在静脉注射后导致病毒持续存在。

Rosen, Lee S; Ottensmeier, Christian; Hawkins, Maria; Naing, Aung; Sonpavde, Guru; Van Tine, Brian A; Parkes, Eileen E; O'Cathail, Sean M; Ji, Rui-Ru; Thomas, Matthew; Stacey, Andrea; Sasso, Maria Stella; Rosen, Oliver

First-in-human clinical outcomes with NG-350A, an anti-CD40 expressing tumor-selective vector designed to remodel immunosuppressive tumor microenvironments

NG-350A是一种表达抗CD40的肿瘤选择性载体,旨在重塑免疫抑制性肿瘤微环境,其首次人体临床试验结果已公布。

Naing, Aung; Khalil, Danny; Rosen, Oliver; Camidge, D Ross; Lillie, Tom; Ji, Rui-Ru; Stacey, Andrea; Thomas, Matthew; Rosen, Lee

Editorial: Treating solid organ diseases with innovative chimeric-antigen receptor T-cells: current indications, progress, limitations and potential strategies

社论:利用创新型嵌合抗原受体T细胞治疗实体器官疾病:当前适应症、进展、局限性和潜在策略

Quackenbush, Elizabeth; Vijayaraghavan, Jyothi; Ozay, Emrah Ilker; Ji, Rui-Ru

Phase 1 study to determine the safety and dosing of autologous PBMCs modified to present HPV16 antigens (SQZ-PBMC-HPV) in HLA-A*02+ patients with HPV16+ solid tumors

一项旨在确定自体外周血单核细胞经修饰可呈递 HPV16 抗原 (SQZ-PBMC-HPV) 在 HLA-A*02+ HPV16+ 实体瘤患者中的安全性和剂量的 1 期研究

Jimeno, Antonio; Baranda, Joaquina; Iams, Wade T; Park, Jong Chul; Mita, Monica; Gordon, Michael S; Taylor, Matthew; Dhani, Neesha; Leal, Alexis D; Neupane, Prakash; Eng, Cathy; Yeku, Oladapo; Mita, Alain; Moser, Justin C; Butler, Marcus; Loughhead, Scott M; Jennings, Julia; Miselis, Nathan R; Ji, Rui-Ru; Nair, Nitya; Kornacker, Martin; Zwirtes, Ricardo F; Bernstein, Howard; Sharei, Armon

Gene expression profiling of whole blood in ipilimumab-treated patients for identification of potential biomarkers of immune-related gastrointestinal adverse events

对接受伊匹木单抗治疗的患者全血进行基因表达谱分析,以识别免疫相关胃肠道不良事件的潜在生物标志物

Shahabi, Vafa; Berman, David; Chasalow, Scott D; Wang, Lisu; Tsuchihashi, Zenta; Hu, Beihong; Panting, Lisa; Jure-Kunkel, Maria; Ji, Rui-Ru

FDR-FET: an optimizing gene set enrichment analysis method

FDR-FET:一种优化的基因集富集分析方法

Ji, Rui-Ru; Ott, Karl-Heinz; Yordanova, Roumyana; Bruccoleri, Robert E

Transcriptional profiling of the dose response: a more powerful approach for characterizing drug activities.

剂量反应的转录组分析:一种更强大的表征药物活性的方法

Ji Rui-Ru, de Silva Heshani, Jin Yisheng, Bruccoleri Robert E, Cao Jian, He Aiqing, Huang Wenjun, Kayne Paul S, Neuhaus Isaac M, Ott Karl-Heinz, Penhallow Becky, Cockett Mark I, Neubauer Michael G, Siemers Nathan O, Ross-Macdonald Petra