Jia Wenqing相关文献与解析，生知库 | 链接生命科学的每一步

Pathogenic role of mitochondrial DNA mutations in heart failure: clinical features, mechanisms, and therapeutic prospects

线粒体DNA突变在心力衰竭中的致病作用：临床特征、机制和治疗前景

doi:10.3389/fcvm.2026.1781927

Ni, Mingyang; Zheng, Aijia; Zheng, Hang; Jia, Wenqing; Wang, Yuansheng; Peng, Yuqing; Yao, Chenguang; Wei, Yanhong; Wang, Xueli; Kang, Sini

Ara-C suppresses H3 K27-altered spinal cord diffuse midline glioma growth and enhances immune checkpoint blockade sensitivity.

阿糖胞苷可抑制 H3 K27 改变的脊髓弥漫性中线胶质瘤的生长，并增强免疫检查点阻断的敏感性

期刊:Science Advances

影响因子:12.5

doi:10.1126/sciadv.adu3956

Pang Bo, Wu Yilin, An SongYuan, Chang Yuzhou, Yan Hao, Lin Han, Zhao Zheng, Wu Fan, Chang Qing, Jia Wenqing, Jiang Tao, Wang Yongzhi, Chai Ruichao

Multi-omics profiling of metastatic colorectal cancer reveals the transcriptional network of focal adhesion and immune suppression and the role of p-RPS6.

转移性结直肠癌的多组学分析揭示了粘着斑和免疫抑制的转录网络以及 p-RPS6 的作用

期刊:Cancer Cell International

影响因子:6

doi:10.1186/s12935-025-03924-6

Jiang Yimei, Li Zhe, Zheng Fang, Jia Wenqing, Guo Zichao, Xu Zhuoqing, Huang Chenhao, Li Zhiliang, Wang Changgang, Liu Kun, Feng Haoran, Zhao Ren, Cheng Xi

Cross-cohort multi-omics analysis identifies novel clusters driven by EMT signatures in colorectal cancer

跨队列多组学分析揭示结直肠癌中由EMT特征驱动的新型细胞簇

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2025.1628005

Ning, Wu; Jia, Wenqing; Ning, Jingyuan; Zhou, Lei; Li, Zongze; Zhang, Lin; Song, Xin

In Silico Discovery of a Novel Natural Product Targeting PI3Kα for the Treatment of Head and Neck Squamous Cell Carcinoma

利用计算机模拟发现一种靶向PI3Kα的新型天然产物用于治疗头颈部鳞状细胞癌

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms26083565

Jia, Wenqing; Cheng, Xianchao

Multi-omics analysis delineates molecular signatures of spinal ependymal tumor

多组学分析揭示脊髓室管膜瘤的分子特征

期刊:Cellular Oncology

影响因子:4.8

doi:10.1007/s13402-025-01122-0

Liu, Weihao; Ning, Chao; Geng, Xiaohan; Wang, Bo; Zhang, Yaowu; Wang, Chong; Liu, Yixiang; Zheng, Guanghao; Wang, Yongzhi; Wang, Xinyu; Li, Dong; Jia, Wenqing

神经科学

发表日期：2025

文献求助收藏

In silico discovery of a novel potential allosteric PI3Kα inhibitor incorporating 2-oxopropyl urea targeting head and neck squamous cell carcinoma

利用计算机模拟发现一种新型潜在的变构PI3Kα抑制剂，该抑制剂包含2-氧丙基脲，靶向治疗头颈部鳞状细胞癌。

期刊:BMC Chemistry

影响因子:4.6

doi:10.1186/s13065-025-01420-6

Jia, Wenqing; Li, Guangzhuang; Cheng, Xianchao; Zhang, Ruijie; Ma, Yukui

Interspecific Hybridization Barrier Between Paeonia ostii and P. ludlowii

芍药属（Paeonia）奥氏芍药（Paeonia ostii）和路德洛芍药（P. ludlowii）之间的种间杂交屏障

期刊:Plants-Basel

影响因子:4.1

doi:10.3390/plants14071120

Guo, Yingzi; Zhang, Yan; Wang, Yanli; Zhao, Guodong; Jia, Wenqing; He, Songlin

发表日期：2025

文献求助收藏

Non-Target Metabolomics Reveals Changes in Metabolite Profiles in Distant Hybrid Incompatibility Between Paeonia sect. Moutan and P. lactiflora

非靶向代谢组学揭示牡丹组和乳白芍药远缘杂交不亲和性中代谢物谱的变化

期刊:Plants-Basel

影响因子:4.1

doi:10.3390/plants14091381

Jia, Wenqing; Yu, Yingyue; Mi, Zhaorong; Zhang, Yan; Zhao, Guodong; Guo, Yingzi; Wang, Zheng; Wang, Erqiang; He, Songlin

代谢

发表日期：2025

文献求助收藏

Clinical features and long-term surgical outcomes of conus medullaris hemangioblastomas

圆锥血管母细胞瘤的临床特征和长期手术结果

Pathogenic role of mitochondrial DNA mutations in heart failure: clinical features, mechanisms, and therapeutic prospects

线粒体DNA突变在心力衰竭中的致病作用：临床特征、机制和治疗前景

Ara-C suppresses H3 K27-altered spinal cord diffuse midline glioma growth and enhances immune checkpoint blockade sensitivity.

阿糖胞苷可抑制 H3 K27 改变的脊髓弥漫性中线胶质瘤的生长，并增强免疫检查点阻断的敏感性

Multi-omics profiling of metastatic colorectal cancer reveals the transcriptional network of focal adhesion and immune suppression and the role of p-RPS6.

转移性结直肠癌的多组学分析揭示了粘着斑和免疫抑制的转录网络以及 p-RPS6 的作用

Cross-cohort multi-omics analysis identifies novel clusters driven by EMT signatures in colorectal cancer

跨队列多组学分析揭示结直肠癌中由EMT特征驱动的新型细胞簇

In Silico Discovery of a Novel Natural Product Targeting PI3Kα for the Treatment of Head and Neck Squamous Cell Carcinoma

利用计算机模拟发现一种靶向PI3Kα的新型天然产物用于治疗头颈部鳞状细胞癌

Multi-omics analysis delineates molecular signatures of spinal ependymal tumor

多组学分析揭示脊髓室管膜瘤的分子特征

In silico discovery of a novel potential allosteric PI3Kα inhibitor incorporating 2-oxopropyl urea targeting head and neck squamous cell carcinoma

利用计算机模拟发现一种新型潜在的变构PI3Kα抑制剂，该抑制剂包含2-氧丙基脲，靶向治疗头颈部鳞状细胞癌。

Interspecific Hybridization Barrier Between Paeonia ostii and P. ludlowii

芍药属（Paeonia）奥氏芍药（Paeonia ostii）和路德洛芍药（P. ludlowii）之间的种间杂交屏障

Non-Target Metabolomics Reveals Changes in Metabolite Profiles in Distant Hybrid Incompatibility Between Paeonia sect. Moutan and P. lactiflora

非靶向代谢组学揭示牡丹组和乳白芍药远缘杂交不亲和性中代谢物谱的变化