Glycyrrhizic acid combined with human adipose-derived MSCs synergistically alleviates the MPP+/MPTP-induced parkinson's disease by inducing autophagy through PI3K/AKT/HIF-1α pathway
甘草酸与人脂肪来源间充质干细胞(MSCs)联合应用,可通过PI3K/AKT/HIF-1α通路诱导自噬,协同缓解MPP+/MPTP诱导的帕金森病。
期刊:Stem Cell Research & Therapy
影响因子:7.3
doi:10.1186/s13287-025-04626-6
Yu, Xinlang; Fang, Yuan; Zhang, Jiakang; Li, Wenshan; Zhang, Yajie; Cui, Qi; Liu, Xiaoyu; Jiang, Yanjie; Liu, Qizhi; Xu, Chengcheng; Jiang, Bin; Lu, Yan
发育与干细胞
信号转导
帕金森
神经科学
多发性硬化症
干细胞
细胞生物学
AKT
自噬