Long non-coding RNA HOTAIR drives EZH2-dependent myofibroblast activation in systemic sclerosis through miRNA 34a-dependent activation of NOTCH
长链非编码RNA HOTAIR通过miRNA 34a依赖性NOTCH激活,驱动系统性硬化症中EZH2依赖性肌成纤维细胞活化。
期刊:Annals of the Rheumatic Diseases
影响因子:20.6
doi:10.1136/annrheumdis-2019-216542
Wasson, Christopher W; Abignano, Giuseppina; Hermes, Heidi; Malaab, Maya; Ross, Rebecca L; Jimenez, Sergio A; Chang, Howard Y; Feghali-Bostwick, Carol A; Del Galdo, Francesco
成纤维细胞
OTC
NOTCH
miRNA
系统性硬化症
EZH2
细胞生物学
免疫/内分泌