日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cancer genomic profiling predicts pathogenicity of BRCA1 and BRCA2 variants

癌症基因组分析预测BRCA1和BRCA2变异的致病性

Kondrashova, Olga; Johnston, Rebecca L; Parsons, Michael T; Davidson, Aimee L; Canson, Daffodil M; Tran, Khoa A; Cline, Melissa S; Waddell, Nicola; Sivakumar, Smruthy; Sokol, Ethan S; Jin, Dexter X; Pavlick, Dean C; Decker, Brennan; Frampton, Garrett M; Spurdle, Amanda B

Clinical Context Shapes the Relationship between Genomic Alterations and Response to AR Inhibitors and Chemotherapy in Metastatic Prostate Cancer.

临床背景决定了转移性前列腺癌中基因组改变与 AR 抑制剂和化疗反应之间的关系

Shah Kalpit, Secrest Matthew H, Zhou Wei, Wang Shu, Canter Dan, Zhang Yuxiang, Jin Dexter, Sokol Ethan, Nowicka Malgorzata, Ang Houle Armande, Metcalfe Ciara, Gendreau Steven, Schröder Carsten, Wongchenko Matthew, Attard Gerhardt

KRAS Codon-Specific Mutations Differentially Toggle PI3K Pathway Signaling and Alter Sensitivity to Inavolisib (GDC-0077).

KRAS 密码子特异性突变差异性地切换 PI3K 通路信号传导并改变对 Inavolisib (GDC-0077) 的敏感性。

Song Kyung W, Ong Christy C, Lin Eva, Lau Jeff, Sodir Nicole M, Jin Dexter X, Hutchinson Katherine E, Xie Shiqi, Tan Jenille, Liang Yuxin, Modrusan Zora, Martin Scott E, Maddalo Danilo, Hafner Marc, Dey Anwesha

Real-World Validity of Tissue-Agnostic Circulating Tumor DNA Response Monitoring in Lung Cancers Treated With Chemotherapy, Immunotherapy, or Targeted Agents

组织非特异性循环肿瘤DNA反应监测在接受化疗、免疫疗法或靶向药物治疗的肺癌患者中的真实世界有效性

Chiang, Anne C; Madison, Russell W; Assaf, Zoe June; Fine, Alexander; Cao, Yi; Gjoerup, Ole; Huang, Yanmei; Jin, Dexter X; Hughes, Jason; Antic, Vladan; Young, Amanda; Fabrizio, David; Shames, David; Maund, Sophia; Exarchos, Alexia; Lakhanpal, Shailendra; Zuniga, Richard; Pasquina, Lincoln W; Schulze, Katja

Genomic profiling and comparative analysis of male versus female metastatic breast cancer across subtypes

基因组谱分析及不同亚型男性与女性转移性乳腺癌的比较分析

Kadamkulam Syriac, Arun; Nandu, Nitish Singh; Clark, Allison; Tavallai, Mehrad; Jin, Dexter X; Sokol, Ethan; McGregor, Kimberly; Ross, Jeffrey S; Danziger, Natalie; Leone, Jose Pablo

Tumor sequencing of African ancestry reveals differences in clinically relevant alterations across common cancers

对非洲裔人群肿瘤进行测序,揭示了常见癌症中具有临床意义的基因改变存在差异。

Jiagge, Evelyn; Jin, Dexter X; Newberg, Justin Y; Perea-Chamblee, Tomin; Pekala, Kelly R; Fong, Christopher; Waters, Michele; Ma, David; Dei-Adomakoh, Yvonne; Erb, Gilles; Arora, Kanika S; Maund, Sophia L; Njiraini, Njoki; Ntekim, Atara; Kim, Susie; Bai, Xuechun; Thomas, Marlene; van Eeden, Ronwyn; Hegde, Priti; Jee, Justin; Chakravarty, Debyani; Schultz, Nikolaus; Berger, Michael F; Frampton, Garrett M; Sokol, Ethan S; Carrot-Zhang, Jian

Homologous Recombination Deficiency Landscape of Breast Cancers and Real-World Effectiveness of Poly ADP-Ribose Polymerase Inhibitors in Patients With Somatic BRCA1/2, Germline PALB2, or Homologous Recombination Deficiency Signature

乳腺癌同源重组缺陷图谱及聚ADP核糖聚合酶抑制剂在具有体细胞BRCA1/2、种系PALB2或同源重组缺陷特征的患者中的真实世界疗效

Batalini, Felipe; Madison, Russell W; Sokol, Ethan S; Jin, Dexter X; Chen, Kuei-Ting; Decker, Brennan; Pavlick, Dean C; Frampton, Garrett M; Wulf, Gerburg M; Garber, Judy E; Oxnard, Geoffrey; Schrock, Alexa B; Tung, Nadine M

A pan-sarcoma landscape of telomeric content shows that alterations in RAD51B and GID4 are associated with higher telomeric content

泛肉瘤端粒含量图谱显示,RAD51B 和 GID4 的改变与较高的端粒含量相关。

Sharaf, Radwa; Jin, Dexter X; Grady, John; Napier, Christine; Ebot, Ericka; Frampton, Garrett M; Albacker, Lee A; Thomas, David M; Montesion, Meagan

A Novel HRD Signature Is Predictive of FOLFIRINOX Benefit in Metastatic Pancreatic Cancer

新型HRD特征可预测转移性胰腺癌患者接受FOLFIRINOX方案的疗效

Chen, Kuei-Ting; Madison, Russell; Moore, Jay; Jin, Dexter; Fleischmann, Zoe; Newberg, Justin; Schrock, Alexa; Bhardwaj, Neeru; Lofgren, Katherine T; He, Jie; Frampton, Garrett; Hegde, Priti; Fabrizio, David; Pishvaian, Michael J; Ebot, Ericka; Singhi, Aatur; Sokol, Ethan

Gene partners of the EWSR1 fusion may represent molecularly distinct entities

EWSR1融合基因的伴侣可能代表分子上不同的实体。

Walker, Victoria; Jin, Dexter X; Millis, Sherri Z; Nasri, Elham; Corao-Uribe, Diana A; Tan, Aik Choon; Fridley, Brooke L; Chen, James L; Seligson, Nathan D