Jin Dong-Yan相关文献与解析，生知库 | 链接生命科学的每一步

Centrosome protein TAX1BP2 mediates STING-dependent immune response and potentiates anti-PD-1 efficacy in hepatocellular carcinoma.

中心体蛋白 TAX1BP2 介导 STING 依赖性免疫反应，并增强抗 PD-1 在肝细胞癌中的疗效

doi:10.1016/j.ymthe.2025.01.043

Zhang Qingmei, Chan Wing-Lim, Fung Sin-Yee, Pang Li, Ding Tao, Teo Jia Ming Nickolas, Zhou Yuan, Wu Chung Ming Alex, Siu Kam-Leung, Bi Jiacheng, Ling Guang Sheng, Jin Dong-Yan, Man Kwan, Ching Yick Pang

A live attenuated SARS-CoV-2 vaccine constructed by dual inactivation of NSP16 and ORF3a.

通过对 NSP16 和 ORF3a 进行双重灭活构建的减毒活 SARS-CoV-2 疫苗

期刊:EBioMedicine

影响因子:10.8

doi:10.1016/j.ebiom.2025.105662

Ye Zi-Wei, Ong Chon Phin, Cao Hehe, Tang Kaiming, Gray Victor Sebastien, Hinson Cheung Pak-Hin, Wang Junjue, Li Weixin, Zhang Hongzhuo, Luo Peng, Ni Tao, Chan Chi Ping, Zhang Ming, Zhang Yuntao, Ling Guang Sheng, Yuan Shuofeng, Jin Dong-Yan

Cgref1 is a CREB-H-regulated hepatokine that promotes hepatic de novo lipogenesis by mediating epididymal fat insulin resistance

Cgref1 是一种受 CREB-H 调控的肝脏因子，它通过介导附睾脂肪的胰岛素抵抗来促进肝脏从头脂肪生成。

期刊:International Journal of Biological Sciences

影响因子:10

doi:10.7150/ijbs.97008

Chan, Pearl; Cheung, Pak-Hin Hinson; Kang, Xiao-Zhuo; Cheng, Yun; Wong, Chi-Ming; Jin, Dong-Yan; Chan, Chi-Ping

Integrin β4-Enriched Small Extracellular Vesicle as Drug Delivery Vehicle for Targeting Pulmonary Metastasis of Hepatocellular Carcinoma

富含整合素β4的小细胞外囊泡作为药物递送载体靶向肝细胞癌肺转移

期刊:Advanced Healthcare Materials

影响因子:9.6

doi:10.1002/adhm.202502649

Ng, Tung Him; Liang, Aijun; Yeung, Maximus Cf; Tey, Sze Keong; Siu, Kam-Leung; Fung, Sin-Yee; Jin, Dong-Yan; Yam, Judy Wai Ping

Mpox virus poxin-schlafen fusion protein suppresses innate antiviral response by sequestering STAT2

Mpox 病毒 poxin-schlafen 融合蛋白通过隔离 STAT2 抑制先天抗病毒反应

期刊:Emerging Microbes & Infections

影响因子:7.5

doi:10.1080/22221751.2025.2477639

Chan, Pearl; Ye, Zi-Wei; Zhao, Wenlong; Ong, Chon-Phin; Sun, Xiao-Yu; Cheung, Pak-Hin Hinson; Jin, Dong-Yan

PKCα Phosphorylates FACI to Switch Its Function in Clathrin-mediated Endocytosis to a Presumed Role in Macropinocytosis in Intestinal and Hepatic Cells

PKCα 磷酸化 FACI，使其在网格蛋白介导的内吞作用中的功能转变为在肠道和肝脏细胞中巨胞饮作用中发挥假定作用。

期刊:Cellular and Molecular Gastroenterology and Hepatology

影响因子:7.4

doi:10.1016/j.jcmgh.2025.101551

Cheng, Yun; Kang, Xiao-Zhuo; Fung, Sin-Yee; Siu, Kam-Leung; Jin, Dong-Yan

C1orf115 interacts with clathrin adaptors to undergo endocytosis and induces ABCA1 to promote enteric cholesterol efflux

C1orf115 与网格蛋白衔接蛋白相互作用，从而进行内吞作用，并诱导 ABCA1 表达，促进肠道胆固醇外流。

期刊:Cellular and Molecular Life Sciences

影响因子:6.2

doi:10.1007/s00018-025-05590-3

Kang, Xiao-Zhuo; Jin, Dong-Yan; Cheng, Yun

CRISPR/Cas13-Mediated Inhibition of EBNA1 for Suppression of Epstein-Barr Virus Transcripts and DNA Load in Nasopharyngeal Carcinoma Cells

利用 CRISPR/Cas13 介导的 EBNA1 抑制来抑制鼻咽癌细胞中的 Epstein-Barr 病毒转录本和 DNA 载量

期刊:Viruses-Basel

影响因子:3.5

doi:10.3390/v17070899

Lin, Lin; Lui, Wai-Yin; Ong, Chon Phin; Yau, Mabel Yin-Chun; Jin, Dong-Yan; Yuen, Kit-San

Oncostatin M for Anti-HBV Therapy: Can a Foe Be Turned Into a Friend?

抗癌药Oncostatin M用于抗HBV治疗：能否化敌为友？

期刊:Cellular and Molecular Gastroenterology and Hepatology

影响因子:7.4

doi:10.1016/j.jcmgh.2023.11.005

Cheng, Tao; Cheng, Yun; Jin, Dong-Yan

C-terminal tail of MAVS dictates organelle targeting and innate immune response

MAVS的C端尾部决定其对细胞器的靶向定位和先天免疫反应。

Centrosome protein TAX1BP2 mediates STING-dependent immune response and potentiates anti-PD-1 efficacy in hepatocellular carcinoma.

中心体蛋白 TAX1BP2 介导 STING 依赖性免疫反应，并增强抗 PD-1 在肝细胞癌中的疗效

A live attenuated SARS-CoV-2 vaccine constructed by dual inactivation of NSP16 and ORF3a.

通过对 NSP16 和 ORF3a 进行双重灭活构建的减毒活 SARS-CoV-2 疫苗

Cgref1 is a CREB-H-regulated hepatokine that promotes hepatic de novo lipogenesis by mediating epididymal fat insulin resistance

Cgref1 是一种受 CREB-H 调控的肝脏因子，它通过介导附睾脂肪的胰岛素抵抗来促进肝脏从头脂肪生成。

Integrin β4-Enriched Small Extracellular Vesicle as Drug Delivery Vehicle for Targeting Pulmonary Metastasis of Hepatocellular Carcinoma

富含整合素β4的小细胞外囊泡作为药物递送载体靶向肝细胞癌肺转移

Mpox virus poxin-schlafen fusion protein suppresses innate antiviral response by sequestering STAT2

Mpox 病毒 poxin-schlafen 融合蛋白通过隔离 STAT2 抑制先天抗病毒反应

PKCα Phosphorylates FACI to Switch Its Function in Clathrin-mediated Endocytosis to a Presumed Role in Macropinocytosis in Intestinal and Hepatic Cells

PKCα 磷酸化 FACI，使其在网格蛋白介导的内吞作用中的功能转变为在肠道和肝脏细胞中巨胞饮作用中发挥假定作用。

C1orf115 interacts with clathrin adaptors to undergo endocytosis and induces ABCA1 to promote enteric cholesterol efflux

C1orf115 与网格蛋白衔接蛋白相互作用，从而进行内吞作用，并诱导 ABCA1 表达，促进肠道胆固醇外流。

CRISPR/Cas13-Mediated Inhibition of EBNA1 for Suppression of Epstein-Barr Virus Transcripts and DNA Load in Nasopharyngeal Carcinoma Cells

利用 CRISPR/Cas13 介导的 EBNA1 抑制来抑制鼻咽癌细胞中的 Epstein-Barr 病毒转录本和 DNA 载量

Oncostatin M for Anti-HBV Therapy: Can a Foe Be Turned Into a Friend?

抗癌药Oncostatin M用于抗HBV治疗：能否化敌为友？