日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Systematic Engineering of Proteases in Saccharopolyspora Spinosa Reveals Synergistic Enhancement of Spinosad Biosynthesis via Substrate Flux Optimization

对棘孢糖多孢菌蛋白酶进行系统性改造，揭示了通过底物通量优化协同增强棘孢菌素生物合成的作用。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202522638
Jin, Duo; Chen, Wangqiong; Yang, Danlu; Liu, Qing; Bai, Baolong; Dai, Zirui; Liu, Xirong; Zhu, Zirong; Rang, Jie; Xia, Liqiu
发表日期：2026
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Enhanced spinosad production in Saccharopolyspora spinosa by employing mannose as an extracellular carbon reservoir and optimizing acetyl-CoA supply pathway

利用甘露糖作为胞外碳源并优化乙酰辅酶A供应途径，提高棘孢菌素的产量

期刊:Synthetic and Systems Biotechnology
影响因子:4.4
doi:10.1016/j.synbio.2026.01.031
Zhu, Zirong; Zhao, Qin; Zhu, Yan; Shuai, Ling; Li, Jun; Liu, Qing; Liu, Xirong; Wang, Shanrui; Jin, Duo; Dai, Zirui; Xia, Liqiu; Liu, Hongrong; Rang, Jie
发表日期：2026
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Integrating Robotic Bilateral Axillo-Breast Approach Thyroidectomy with Molecular Diagnostics and Artificial Intelligence in Thyroid Cancer Care

将机器人辅助双侧腋乳入路甲状腺切除术与分子诊断和人工智能相结合应用于甲状腺癌治疗

期刊:Biomolecules & Therapeutics
影响因子:3.2
doi:10.4062/biomolther.2025.125
Deng, Qiang; Men, Xiaoping; Jin, Duo; Bai, Yuzhuo
甲状腺癌
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2026
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Provoking tumor disulfidptosis by single-atom nanozyme via regulating cellular energy supply and reducing power.

通过单原子纳米酶调节细胞能量供应和还原力来诱导肿瘤二硫键凋亡

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-60015-w
Yu Wenxin, Jin Duo, Zhang Yajie, Wang Shenghu, Yu Jiaji, Liu Manman, Dai Yi, Yin Yichen, Cheng Junjie, Liu Yangzhong
肿瘤
凋亡
发表日期：2025
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Beyond molecular chaperoning: AHA1 reprograms autophagy flux through direct ATP5A1 interaction in ischemic neuronal injury

超越分子伴侣作用：AHA1通过与ATP5A1的直接相互作用，在缺血性神经元损伤中重编程自噬通量

期刊:Redox Biology
影响因子:11.9
doi:10.1016/j.redox.2025.103920
Jin, Duo; Ge, Xinran; Liu, Li; Jia, Yujie; Liu, Chang; Meng, Ke; Zhang, Xiaowei
自噬
神经科学
发表日期：2025
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Venetoclax synergizes with Wnt/β-catenin inhibitor C-82 in acute myeloid leukemia by increasing the degradation of Mcl-1 protein.

Venetoclax 与 Wnt/β-catenin 抑制剂 C-82 在急性髓系白血病中具有协同作用，可增加 Mcl-1 蛋白的降解

期刊:Cancer Cell International
影响因子:6
doi:10.1186/s12935-025-03825-8
Pan Mengya, Jiao Changqing, Sun Menghua, Jin Duo, Wang Yin, Wu Haoxuan, Zhang Yan, Chen Enbo, Su Bobin, Zhou Junjie, Liu Xiaoying, Ge Jian
肿瘤
白血病
Wnt/β-Catenin
发表日期：2025
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Hypoxia-induced tRF-3(Thr-CGT) promotes hepatocellular carcinoma progression via mitochondrial energy metabolism remodeling dependent on the mtDNA-translation mechanism.

缺氧诱导的 tRF-3(Thr-CGT) 通过依赖于 mtDNA 翻译机制的线粒体能量代谢重塑促进肝细胞癌的进展

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2025.1549373
Qu Xianzhi, Liu Buhan, Jin Duo, Ma Yue, Liu Mingjun, Yan Xiaoyu, Su Jing, Zhou Lei
代谢
线粒体
发表日期：2025
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Coordinated regulation of propionyl-CoA carboxylase subunits drives precursor flux optimization in spinosad production

丙酰辅酶A羧化酶亚基的协同调控驱动多杀菌素生产中前体通量的优化

期刊:Frontiers in Microbiology
影响因子:4.5
doi:10.3389/fmicb.2025.1643527
Xia, Ziyuan; Li, Xiaomin; Liu, Xirong; Cao, Li; Jin, Duo; Dai, Zirui; Bai, Baolong; Liu, Qian; Rang, Jie; Zhu, Zirong; Xia, Liqiu
信号转导
发表日期：2025
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CRISPRi-mediated multigene downregulating redirects the metabolic flux to spinosad biosynthesis in Saccharopolyspora spinosa

CRISPRi介导的多基因下调将代谢流重定向至棘孢菌素的生物合成

期刊:Synthetic and Systems Biotechnology
影响因子:4.4
doi:10.1016/j.synbio.2025.02.010
Zhu, Zirong; Cao, Li; Xia, Ziyuan; Liu, Xirong; Chen, Wangqion; Dai, Zirui; Jin, Duo; Rang, Jie; Hu, Shengbiao; Xia, Liqiu
代谢
发表日期：2025
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Significance of ARID1A in neuroblastoma onset mechanism

ARID1A在神经母细胞瘤发病机制中的意义

期刊:Frontiers in Oncology
影响因子:3.3
doi:10.3389/fonc.2025.1624561
Jin, Duo; Zhang, Dong; Tang, Qinyu
细胞生物学
ID1
发表日期：2025
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