日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery of a non-nucleoside inhibitor that binds to a novel site in the palm domain of the respiratory syncytial virus RNA-dependent RNA polymerase.

发现一种非核苷类抑制剂,可与呼吸道合胞病毒 RNA 依赖性 RNA 聚合酶掌状结构域中的新位点结合

Kalin Jay H, Yin Yanting, Tran Minh T, Piassek Madison, Fung Amy, Grosse Sandrine, Jacoby Edgar, Bhaumik Anusarka, Adhikary Suraj, Miller Robyn, Lemmens Cynthia, Lutter Ferdinand H, Pieters Serge, Cooymans Ludwig, Rombouts Geert, Oehlrich Daniel, Tomaso Sonia, Lozada Kate, Garcia Miguel Osorio, Anson Brandon, De Bruyn Suzanne, Smith-Monroy Constance, Neefs Jean-Marc, Conceição-Neto Nádia, Stoops Bart, van Vlijmen Herman, Patrick Aaron, Yu Xiaodi, Wong Victoria, Krosky Daniel, Abeywickrema Pravien, Mason Stephen, Jin Zhinan, Jonckers Tim H M, Sharma Sujata

The role of AFAP1-AS1 in mitotic catastrophe and metastasis of triple-negative breast cancer cells by activating the PLK1 signaling pathway

AFAP1-AS1 通过激活 PLK1 信号通路在三阴性乳腺癌细胞有丝分裂灾难和转移中的作用

Shuizhong Cen, Xiaojie Peng, Jianwen Deng, Haiyun Jin, Zhinan Deng, Xiaohua Lin, D I Zhu, Ming Jin, Yanwen Zhu, Pusheng Zhang, Yunfeng Luo, Hongyan Huang

Donor γδT Cells Promote GVL Effect and Mitigate aGVHD in Allogeneic Hematopoietic Stem Cell Transplantation

供体 γδT 细胞促进异基因造血干细胞移植中的 GVL 效应并减轻 aGVHD

Yuan Song, Ying Zhu, Bo Hu, Yonghao Liu, Dandan Lin, Ziqi Jin, Zhinan Yin, Chen Dong, Depei Wu, Haiyan Liu

Molecular Basis for the Selective Inhibition of Respiratory Syncytial Virus RNA Polymerase by 2'-Fluoro-4'-Chloromethyl-Cytidine Triphosphate

2'-氟-4'-氯甲基胞苷三磷酸选择性抑制呼吸道合胞病毒RNA聚合酶的分子机制

Deval, Jerome; Hong, Jin; Wang, Guangyi; Taylor, Josh; Smith, Lucas K; Fung, Amy; Stevens, Sarah K; Liu, Hong; Jin, Zhinan; Dyatkina, Natalia; Prhavc, Marija; Stoycheva, Antitsa D; Serebryany, Vladimir; Liu, Jyanwei; Smith, David B; Tam, Yuen; Zhang, Qingling; Moore, Martin L; Fearns, Rachel; Chanda, Sushmita M; Blatt, Lawrence M; Symons, Julian A; Beigelman, Leo

Efficiency of incorporation and chain termination determines the inhibition potency of 2'-modified nucleotide analogs against hepatitis C virus polymerase

掺入效率和链终止效率决定了2'-修饰核苷酸类似物对丙型肝炎病毒聚合酶的抑制效力。

Fung, Amy; Jin, Zhinan; Dyatkina, Natalia; Wang, Guangyi; Beigelman, Leo; Deval, Jerome

Role of a GAG hinge in the nucleotide-induced conformational change governing nucleotide specificity by T7 DNA polymerase

GAG铰链在T7 DNA聚合酶核苷酸诱导的构象变化中的作用,该变化控制着核苷酸特异性

Jin, Zhinan; Johnson, Kenneth A