Jin-Ran Chen相关文献与解析，生知库 | 链接生命科学的每一步

Dongzheng Gai, Perry C Caviness, Oxana P Lazarenko, Jennifer F Chen, Christopher E Randolph, Zijun Zhang, Yan Cheng, Fumou Sun, Hongwei Xu, Michael L Blackburn, Guido Tricot, John D Shaughnessy Jr, Jin-Ran Chen, Fenghuang Zhan

肿瘤

骨髓瘤

发表日期：2025

文献求助收藏

BCMA- and CST6-specific CAR T cells lyse multiple myeloma cells and suppress murine osteolytic lesions

BCMA和CST6特异性CAR T细胞可裂解多发性骨髓瘤细胞并抑制小鼠溶骨性病变

期刊:Journal of Clinical Investigation

影响因子:13.3

doi:10.1172/JCI171396

Fumou Sun ，Yan Cheng ，Jin-Ran Chen ，Visanu Wanchai ，David E Mery ，Hongwei Xu ，Dongzheng Gai ，Samer Al Hadidi ，Carolina Schinke ，Sharmilan Thanendrarajan ，Maurizio Zangari ，Frits van Rhee ，Guido Tricot ，John D Shaughnessy Jr ，Fenghuang Zhan

Cystatin M/E ameliorates bone resorption through increasing osteoclastic cell estrogen influx

胱抑素 M/E 通过增加破骨细胞雌激素流入来改善骨吸收

期刊:

影响因子:

doi:10.21203/rs.3.rs-4313179/v1

High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma

髓系祖细胞中高表达的NEK2可抑制多发性骨髓瘤中的T细胞免疫

期刊:Cell Reports Medicine

影响因子:11.7

doi:10.1016/j.xcrm.2023.101214

Yan Cheng ，Fumou Sun ，Daisy V Alapat ，Visanu Wanchai ，David Mery ，Wancheng Guo ，Huojun Cao ，Yuqi Zhu ，Cody Ashby ，Michael Anton Bauer ，Intawat Nookaew ，Eric R Siegel ，Jun Ying ，Jin-Ran Chen ，Dongzheng Gai ，Bailu Peng ，Hongwei Xu ，Clyde Bailey ，Samer Al Hadidi ，Carolina Schinke ，Sharmilan Thanendrarajan ，Maurizio Zangari ，Marta Chesi ，P Leif Bergsagel ，Frits van Rhee ，Siegfried Janz ，Guido Tricot ，John D Shaughnessy Jr ，Fenghuang Zhan

CST6 suppresses osteolytic bone disease in multiple myeloma by blocking osteoclast differentiation

CST6 通过阻断破骨细胞分化来抑制多发性骨髓瘤中的溶骨性骨病

期刊:Journal of Clinical Investigation

影响因子:13.3

doi:10.1172/JCI159527

Dongzheng Gai, Jin-Ran Chen, James P Stewart, Intawat Nookaew, Hasem Habelhah, Cody Ashby, Fumou Sun, Yan Cheng, Can Li, Hongwei Xu, Bailu Peng, Tarun K Garg, Carolina Schinke, Sharmilan Thanendrarajan, Maurizio Zangari, Fangping Chen, Bart Barlogie, Frits van Rhee, Guido Tricot, John D Shaughnessy

Nox4 expression in osteo-progenitors controls bone development in mice during early life

骨祖细胞中的 Nox4 表达控制小鼠早期骨骼发育

期刊:Communications Biology

影响因子:5.2

doi:10.1038/s42003-022-03544-0

Jin-Ran Chen, Oxana P Lazarenko, Michael L Blackburn, Jennifer F Chen, Christopher E Randolph, Jovanny Zabaleta, Katrin Schroder, Kim B Pedersen, Martin J J Ronis

Binge Ethanol Exposure in Mice Represses Expression of Genes Involved in Osteoblast Function and Induces Expression of Genes Involved in Osteoclast Differentiation Independently of Endogenous Catalase

小鼠酗酒暴露抑制了与成骨细胞功能有关的基因表达，并诱导了与破骨细胞分化有关的基因表达，且不依赖于内源性过氧化氢酶

期刊:Toxicological Sciences

影响因子:3.4

doi:10.1093/toxsci/kfab135

Alexandra Denys, Kim B Pedersen, James Watt, Allison R Norman, Michelle L Osborn, Jin-Ran Chen, Cole Maimone, Shana Littleton, Vasilis Vasiliou, Martin J J Ronis

Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice

母体高脂饮食改变骨骼中的表观遗传标记 H3K27me3 和 H3K27ac，从而调节小鼠后代的成骨细胞生成

期刊:Epigenetics

影响因子:2.9

doi:10.1080/15592294.2022.2111759

Jin-Ran Chen, Perry C Caviness, Haijun Zhao, Beau Belcher, Umesh D Wankhade, Kartik Shankar, Michael L Blackburn, Oxana P Lazarenko

Exploring GPR109A Receptor Interaction with Hippuric Acid Using MD Simulations and CD Spectroscopy

使用 MD 模拟和 CD 光谱探索 GPR109A 受体与马尿酸的相互作用

期刊:International Journal of Molecular Sciences

影响因子:0.7

doi:10.3390/ijms232314778

Dipendra Bhandari, Sangita Kachhap, Geet Madhukar, Kiran Kumar Adepu, Andriy Anishkin, Jin-Ran Chen, Sree V Chintapalli

信号转导

发表日期：2022

文献求助收藏

Hippuric acid and 3-(3-hydroxyphenyl) propionic acid inhibit murine osteoclastogenesis through RANKL-RANK independent pathway

马尿酸和 3-（3-羟基苯基）丙酸通过 RANKL-RANK 非依赖途径抑制小鼠破骨细胞生成

期刊:Journal of Cellular Physiology

影响因子:4.5

doi:10.1002/jcp.28998

Haijun Zhao, Oxana P Lazarenko, Jin-Ran Chen

Cystatin M/E Ameliorates Multiple Myeloma-Induced Hyper Osteolytic Bone Resorption

胱抑素 M/E 改善多发性骨髓瘤引起的高溶骨性骨吸收

BCMA- and CST6-specific CAR T cells lyse multiple myeloma cells and suppress murine osteolytic lesions

BCMA和CST6特异性CAR T细胞可裂解多发性骨髓瘤细胞并抑制小鼠溶骨性病变

Cystatin M/E ameliorates bone resorption through increasing osteoclastic cell estrogen influx

胱抑素 M/E 通过增加破骨细胞雌激素流入来改善骨吸收

High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma

髓系祖细胞中高表达的NEK2可抑制多发性骨髓瘤中的T细胞免疫

CST6 suppresses osteolytic bone disease in multiple myeloma by blocking osteoclast differentiation

CST6 通过阻断破骨细胞分化来抑制多发性骨髓瘤中的溶骨性骨病

Nox4 expression in osteo-progenitors controls bone development in mice during early life

骨祖细胞中的 Nox4 表达控制小鼠早期骨骼发育

Binge Ethanol Exposure in Mice Represses Expression of Genes Involved in Osteoblast Function and Induces Expression of Genes Involved in Osteoclast Differentiation Independently of Endogenous Catalase

小鼠酗酒暴露抑制了与成骨细胞功能有关的基因表达，并诱导了与破骨细胞分化有关的基因表达，且不依赖于内源性过氧化氢酶

Maternal high-fat diet modifies epigenetic marks H3K27me3 and H3K27ac in bone to regulate offspring osteoblastogenesis in mice

母体高脂饮食改变骨骼中的表观遗传标记 H3K27me3 和 H3K27ac，从而调节小鼠后代的成骨细胞生成

Exploring GPR109A Receptor Interaction with Hippuric Acid Using MD Simulations and CD Spectroscopy

使用 MD 模拟和 CD 光谱探索 GPR109A 受体与马尿酸的相互作用

Hippuric acid and 3-(3-hydroxyphenyl) propionic acid inhibit murine osteoclastogenesis through RANKL-RANK independent pathway

马尿酸和 3-（3-羟基苯基）丙酸通过 RANKL-RANK 非依赖途径抑制小鼠破骨细胞生成