日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Validating TDP1 as an Inhibition Target for the Development of Chemosensitizers for Camptothecin-Based Chemotherapy Drugs

验证 TDP1 作为喜树碱类化疗药物化学增敏剂开发的抑制靶点

Euphemia Leung #, Jinal Patel #, Jennifer A Hollywood, Ayesha Zafar, Petr Tomek, David Barker, Lisa I Pilkington, Michelle van Rensburg, Ries J Langley, Nuala A Helsby, Christopher J Squire, Bruce C Baguley, William A Denny, Jóhannes Reynisson, Ivanhoe K H Leung

New Hydrazinothiazole Derivatives of Usnic Acid as Potent Tdp1 Inhibitors

松萝酸的新型肼基噻唑衍生物作为有效的 Tdp1 抑制剂

Aleksander S Filimonov, Arina A Chepanova, Olga A Luzina, Alexandra L Zakharenko, Olga D Zakharova, Ekaterina S Ilina, Nadezhda S Dyrkheeva, Maxim S Kuprushkin, Anton V Kolotaev, Derenik S Khachatryan, Jinal Patel, Ivanhoe K H Leung, Raina Chand, Daniel M Ayine-Tora, Johannes Reynisson, Konstantin P

Castration Resistance in Prostate Cancer Is Mediated by the Kinase NEK6

前列腺癌的去势抵抗由激酶 NEK6 介导

Atish D Choudhury, Anna C Schinzel, Maura B Cotter, Rosina T Lis, Katherine Labella, Ying Jie Lock, Francesca Izzo, Isil Guney, Michaela Bowden, Yvonne Y Li, Jinal Patel, Emily Hartman, Steven A Carr, Monica Schenone, Jacob D Jaffe, Philip W Kantoff, Peter S Hammerman, William C Hahn

Reduced-representation Phosphosignatures Measured by Quantitative Targeted MS Capture Cellular States and Enable Large-scale Comparison of Drug-induced Phenotypes

通过定量靶向 MS 测量的简化表征磷特征可捕获细胞状态并实现药物诱导表型的大规模比较

Jennifer G Abelin, Jinal Patel, Xiaodong Lu, Caitlin M Feeney, Lola Fagbami, Amanda L Creech, Roger Hu, Daniel Lam, Desiree Davison, Lindsay Pino, Jana W Qiao, Eric Kuhn, Adam Officer, Jianxue Li, Susan Abbatiello, Aravind Subramanian, Richard Sidman, Evan Snyder, Steven A Carr, Jacob D Jaffe

Reconstituted B cell receptor signaling reveals carbohydrate-dependent mode of activation

重建的 B 细胞受体信号揭示了碳水化合物依赖性的激活模式

Rina F Villar, Jinal Patel, Grant C Weaver, Masaru Kanekiyo, Adam K Wheatley, Hadi M Yassine, Catherine E Costello, Kevin B Chandler, Patrick M McTamney, Gary J Nabel, Adrian B McDermott, John R Mascola, Steven A Carr, Daniel Lingwood

Integrated proteomic analysis of post-translational modifications by serial enrichment

通过连续富集对翻译后修饰进行综合蛋白质组学分析

Philipp Mertins, Jana W Qiao, Jinal Patel, Namrata D Udeshi, Karl R Clauser, D R Mani, Michael W Burgess, Michael A Gillette, Jacob D Jaffe, Steven A Carr

iTRAQ labeling is superior to mTRAQ for quantitative global proteomics and phosphoproteomics

在定量整体蛋白质组学和磷酸化蛋白质组学方面,iTRAQ 标记优于 mTRAQ

Philipp Mertins, Namrata D Udeshi, Karl R Clauser, D R Mani, Jinal Patel, Shao-en Ong, Jacob D Jaffe, Steven A Carr