日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Linavonkibart and pembrolizumab in immune checkpoint blockade-resistant advanced solid tumors: a phase 1 trial.

Linavonkibart 和 pembrolizumab 治疗免疫检查点阻断耐药的晚期实体瘤:一项 1 期试验。

Yap Timothy A, Sweis Randy F, Vaishampayan Ulka, Kilari Deepak, Gainor Justin F, McKean Meredith, Barve Minal, Tarhini Ahmad A, Bockorny Bruno, Sonpavde Guru, Park David, Babu Sunil, Ju Yawen, Liu Lan, Henry Susan, Tirucherai Giridhar S, DeWall Stephen, Qatanani Mohammed, Marantz Jing L, Gan Lu

Decreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes

脂化ApoE与受体相互作用的减少可保护机体免受溶酶体中ApoE及其脂质货物致病性的侵害。

Jing L Guo,Dylan Braun,Gabriel A Fitzgerald,Yun-Ting Hsieh,Lionel Rougé,Alexandra Litvinchuk,Micah Steffek,Nicholas E Propson,Catherine M Heffner,Claire Discenza,Suk Ji Han,Anil Rana,Lukas L Skuja,Bi Qi Lin,Elizabeth W Sun,Sonnet S Davis,Srijana Balasundar,Isabel Becerra,Jason C Dugas,Connie Ha,Jennifer Hsiao-Nakamoto,Fen Huang,Shourya Jain,Jennifer E Kung,Nicholas P D Liau,Cathal S Mahon,Hoang N Nguyen,Nathan Nguyen,Madhuja Samaddar,Yajuan Shi,David Tatarakis,Yuxi Tian,Yuda Zhu,Jung H Suh,Thomas Sandmann,Meredith E K Calvert,Annie Arguello,Lesley A Kane,Joseph W Lewcock,David M Holtzman,Christopher M Koth,Gilbert Di Paolo

The primate-specific Nedd4-1(NE) localizes to late endosomes in response to amino acids to suppress autophagy

灵长类特有的Nedd4-1(NE)在氨基酸的刺激下定位于晚期内体,从而抑制自噬。

Kefalas, G; Priya, A; Astori, A; Persaud, A; Jing, L; Sydor, A M; Yao, H H Y; Warner, N; Zhang, Y; Brumell, J H; Muise, A M; Sari, S; Su, H C; Lenardo, M J; Kahr, W H A; Raught, B; Rotin, D

Germinal Center B Cells are Uniquely Targeted by Antibody-Suppressor CXCR5(+)CD8(+) T Cells

生发中心B细胞是抗体抑制性CXCR5(+)CD8(+) T细胞的独特靶标

Zimmerer, Jason M; Chaudhari, Sachi; Koneru, Kavya; Han, Jing L; Abdel-Rasoul, Mahmoud; Uwase, Hope; Yi, Tai; Breuer, Christopher K; Bumgardner, Ginny L

Hamayou () protein hydrolysate ameliorates depression by regulating the mitogen-activated protein kinase pathway

Hamayou()蛋白水解物通过调节丝裂原活化蛋白激酶通路改善抑郁症状

Weijia, L I; Jing, L U; Chao, M A; Mengmeng, Liu; Ke, Pei; Hongyan, Chen; Zhe, Lin; Guangfu, Lyu

Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist

LXR激动剂可改善Tau蛋白和ApoE4相关的胶质细胞脂质积累和神经退行性变

Alexandra Litvinchuk ,Jung H Suh ,Jing L Guo ,Karin Lin ,Sonnet S Davis ,Nga Bien-Ly ,Eric Tycksen ,G Travis Tabor ,Javier Remolina Serrano ,Melissa Manis ,Xin Bao ,Choonghee Lee ,Megan Bosch ,Enmanuel J Perez ,Carla M Yuede ,Anil G Cashikar ,Jason D Ulrich ,Gilbert Di Paolo ,David M Holtzman

CXCR5 + CD8 + T Cell-mediated Suppression of Humoral Alloimmunity and AMR in Mice Is Optimized With mTOR and Impaired With Calcineurin Inhibition

CXCR5 + CD8 + T 细胞介导的小鼠体液同种免疫和抗体介导的排斥反应的抑制作用可通过 mTOR 优化,而可通过钙调磷酸酶抑制剂削弱。

Han, Jing L; Zimmerer, Jason M; Zeng, Qiang; Chaudhari, Sachi R; Hart, Madison; Satoskar, Anjali A; Abdel-Rasoul, Mahmoud; Breuer, Christopher K; Bumgardner, Ginny L

Revealing the dynamic whole transcriptome landscape of Clonorchis sinensis: Insights into the regulatory roles of noncoding RNAs and microtubule-related genes in development

揭示中华肝吸虫动态的全转录组图谱:深入了解非编码RNA和微管相关基因在发育过程中的调控作用

Qiu, Yangyuan; Wang, Cunzhou; Wang, Jing; L V, Qingbo; Sun, Lulu; Yang, Yaming; Liu, Mingyuan; Liu, Xiaolei; Li, Chen; Tang, Bin

Antibody-Suppressor CXCR5+CD8+ T Cells Are More Potent Regulators of Humoral Alloimmunity after Kidney Transplant in Mice Compared to CD4+ Regulatory T Cells

与 CD4+ 调节性 T 细胞相比,抗体抑制性 CXCR5+CD8+ T 细胞在小鼠肾移植后体液同种异体免疫调节中发挥更有效的作用。

Han, Jing L; Zimmerer, Jason M; Zeng, Qiang; Chaudhari, Sachi; Satoskar, Anjali; Abdel-Rasoul, Mahmoud; Uwase, Hope; Breuer, Christopher K; Bumgardner, Ginny L

Long-term efficacy, safety, and patient-reported outcomes of apitegromab in patients with spinal muscular atrophy: results from the 36-month TOPAZ study

阿匹格罗单抗治疗脊髓性肌萎缩症患者的长期疗效、安全性和患者报告结局:来自 36 个月 TOPAZ 研究的结果

Crawford, Thomas O; Day, John W; De Vivo, Darryl C; Krueger, Jena M; Mercuri, Eugenio; Nascimento, Andres; Pasternak, Amy; Mazzone, Elena Stacy; Duong, Tina; Song, Guochen; Marantz, Jing L; Baver, Scott; Yu, Dongzi; Liu, Lan; Darras, Basil T