Jmaeff相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Alternative Splicing of a Receptor Intracellular Domain Yields Different Ectodomain Conformations, Enabling Isoform-Selective Functional Ligands

受体胞内结构域的选择性剪接产生不同的胞外结构域构象，从而实现异构体选择性功能配体。

期刊:iScience

影响因子:4.1

doi:10.1016/j.isci.2020.101447

Brahimi, Fouad; Galan, Alba; Jmaeff, Sean; Barcelona, Pablo F; De Jay, Nicolas; Dejgaard, Kurt; Young, Jason C; Kleinman, Claudia L; Thomas, David Y; Saragovi, H Uri

发表日期：2020

文献求助收藏

Small-molecule agonists of the RET receptor tyrosine kinase activate biased trophic signals that are influenced by the presence of GFRa1 co-receptors

RET 受体酪氨酸激酶的小分子激动剂可激活受 GFRa1 共受体影响的偏向营养信号

期刊:Journal of Biological Chemistry

doi:10.1074/jbc.RA119.011802

Sean Jmaeff, Yulia Sidorova, Hinyu Nedev, Mart Saarma, H Uri Saragovi

发表日期：2020

文献求助收藏

Small-Molecule Ligands that Bind the RET Receptor Activate Neuroprotective Signals Independent of but Modulated by Coreceptor GFR α 1

与 RET 受体结合的小分子配体激活独立于辅受体 GFR α 1 但受其调节的神经保护信号

期刊:Molecular Pharmacology

影响因子:3.2

doi:10.1124/mol.119.118950

Sean Jmaeff, Yulia Sidorova, Hayley Lippiatt, Pablo F Barcelona, Hinyu Nedev, Lucia M Saragovi, Mark A Hancock, Mart Saarma, H Uri Saragovi

发表日期：2020

文献求助收藏

In retinitis pigmentosa TrkC.T1-dependent vectorial Erk activity upregulates glial TNF-α, causing selective neuronal death

在视网膜色素变性中，TrkC.T1依赖的Erk矢量活性上调神经胶质细胞TNF-α，导致选择性神经元死亡。

期刊:Cell Death & Disease

影响因子:9.6

doi:10.1038/s41419-017-0074-8

Galán, Alba; Jmaeff, Sean; Barcelona, Pablo F; Brahimi, Fouad; Sarunic, Marinko V; Saragovi, H Uri

细胞生物学

发表日期：2017

文献求助收藏

p75NTR antagonists attenuate photoreceptor cell loss in murine models of retinitis pigmentosa

p75NTR 拮抗剂可减轻小鼠视网膜色素变性模型中的感光细胞丢失

期刊:Cell Death & Disease

影响因子:8.1

doi:10.1038/cddis.2017.306

María Platón-Corchado, Pablo F Barcelona, Sean Jmaeff, Miguel Marchena, Alberto M Hernández-Pinto, Catalina Hernández-Sánchez, H Uri Saragovi, Enrique J de la Rosa

细胞生物学

发表日期：2017

文献求助收藏

p75NTR and Its Ligand ProNGF Activate Paracrine Mechanisms Etiological to the Vascular, Inflammatory, and Neurodegenerative Pathologies of Diabetic Retinopathy

p75NTR 及其配体 ProNGF 激活导致糖尿病视网膜病变的血管、炎症和神经退行性疾病的旁分泌机制

期刊:Journal of Neuroscience

影响因子:4.4

doi:10.1523/JNEUROSCI.4278-15.2016

Pablo F Barcelona, Nicholas Sitaras, Alba Galan, Gema Esquiva, Sean Jmaeff, Yifan Jian, Marinko V Sarunic, Nicolas Cuenca, Przemyslaw Sapieha, H Uri Saragovi

发表日期：2016

文献求助收藏