日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The shifting lipidomic landscape of blood monocytes and neutrophils during pneumonia

肺炎期间血液单核细胞和中性粒细胞脂质组学的变化

Alex R Schuurman, Osoul Chouchane, Joe M Butler, Hessel Peters-Sengers, Sebastiaan Joosten, Xanthe Brands, Bastiaan W Haak, Natasja A Otto, Fabrice Uhel, Augustijn Klarenbeek, Christine Ca van Linge, Antoine van Kampen, Mia Pras-Raves, Michel van Weeghel, Marco van Eijk, Maria J Ferraz, Daniël R Fab

Single-cell transcriptomics reveals subset-specific metabolic profiles underpinning the bronchial epithelial response to flagellin

单细胞转录组学揭示了支气管上皮细胞对鞭毛蛋白反应的亚群特异性代谢谱

Ivan Ramirez-Moral ,Alex R Schuurman ,Christine C A van Linge ,Joe M Butler ,Xiao Yu ,Karen de Haan ,Sarah van Leeuwen ,Alex F de Vos ,Menno D de Jong ,Felipe A Vieira Braga ,Tom van der Poll

Inflammatory and glycolytic programs underpin a primed blood neutrophil state in patients with pneumonia

炎症和糖酵解程序是肺炎患者血液中性粒细胞处于活跃状态的基础

Alex R Schuurman, Joe M Butler, Erik H A Michels, Natasja A Otto, Xanthe Brands, Bastiaan W Haak, Fabrice Uhel, Augustijn M Klarenbeek, Daniël R Faber, Bauke V Schomakers, Michel van Weeghel, Alex F de Vos, Brendon P Scicluna, Riekelt H Houtkooper, W Joost Wiersinga, Tom van der Poll

Platelets of COVID-19 patients display mitochondrial dysfunction, oxidative stress, and energy metabolism failure compatible with cell death

COVID-19 患者的血小板表现出线粒体功能障碍、氧化应激和能量代谢衰竭,并伴有细胞死亡

Valentine Léopold, Osoul Chouchane, Joe M Butler, Alex R Schuurman, Erik H A Michels, Justin de Brabander, Bauke V Schomakers, Michel van Weeghel, Daisy I Picavet-Havik, Anita E Grootemaat, Renée A Douma, Tom D Y Reijnders, Augustijn M Klarenbeek, Brent Appelman; Amsterdam University Medical Center

HIF-1α Stabilization in Flagellin-Stimulated Human Bronchial Cells Impairs Barrier Function

鞭毛蛋白刺激的人类支气管细胞中的 HIF-1α 稳定会损害屏障功能

Ivan Ramirez-Moral, Bianca L Ferreira, Joe M Butler, Michel van Weeghel, Natasja A Otto, Alex F de Vos, Xiao Yu, Menno D de Jong, Riekelt H Houtkooper, Tom van der Poll

C/EBPδ Suppresses Motility-Associated Gene Signatures and Reduces PDAC Cell Migration

C/EBPδ 抑制运动相关基因特征并减少 PDAC 细胞迁移

Leonie Hartl, Pien A F Maarschalkerweerd, Joe M Butler, Xue D Manz, Victor L J L Thijssen, Maarten F Bijlsma, JanWillem Duitman, C Arnold Spek

Rectal microbiota are coupled with altered cytokine production capacity following community-acquired pneumonia hospitalization

社区获得性肺炎住院后直肠微生物群与细胞因子产生能力改变有关

Robert F J Kullberg, Xanthe Brands, Augustijn M Klarenbeek, Joe M Butler, Natasja A Otto, Daniël R Faber, Brendon P Scicluna, Tom van der Poll, W Joost Wiersinga, Bastiaan W Haak

HIVEP1 Is a Negative Regulator of NF-κB That Inhibits Systemic Inflammation in Sepsis

HIVEP1 是 NF-κB 的负调节剂,可抑制脓毒症中的全身炎症

Hisatake Matsumoto, Brendon P Scicluna, Kin Ki Jim, Fahimeh Falahi, Wanhai Qin, Berke Gürkan, Erik Malmström, Mariska T Meijer, Joe M Butler, Hina N Khan, Tsuyoshi Takagi, Shunsuke Ishii, Marcus J Schultz, Diederik van de Beek, Alex F de Vos, Cornelis van 't Veer, Tom van der Poll

CEBPD Potentiates the Macrophage Inflammatory Response but CEBPD Knock-Out Macrophages Fail to Identify CEBPD-Dependent Pro-Inflammatory Transcriptional Programs

CEBPD 增强巨噬细胞炎症反应,但 CEBPD 敲除巨噬细胞无法识别 CEBPD 依赖的促炎转录程序

C Arnold Spek, Hella L Aberson, Joe M Butler, Alex F de Vos, JanWillem Duitman

Role of Myeloid Tet Methylcytosine Dioxygenase 2 in Pulmonary and Peritoneal Inflammation Induced by Lipopolysaccharide and Peritonitis Induced by Escherichia coli

髓系四甲基胞嘧啶双加氧酶2在脂多糖诱发的肺、腹膜炎症及大肠杆菌诱发的腹膜炎中的作用

Wanhai Qin, Xanthe Brands, Hisatake Matsumoto, Joe M Butler, Cornelis Van't Veer, Alex F de Vos, Joris J T H Roelofs, Brendon P Scicluna, Tom van der Poll