日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Platelet Autophagy as a Druggable Intracellular Pathway: Therapeutic Opportunities in Thromboinflammatory Diseases

血小板自噬作为一种可药物靶向的细胞内通路:血栓炎症性疾病的治疗契机

Yen, Ting-Lin; Jan, Jing-Shiun; Teng, Ruei-Dun; Ko, Pi-Chan; Taliyan, Rajeev; Yang, Chih-Hao; Sun, Jui-Ming; Sheu, Joen-Rong

Distinct Thromboxane A₂-Dependent Pathways Regulate Arachidonic Acid-Triggered VASP Phosphorylation at Ser239 and Ser157 in Human Platelets: Real-Time Visualization Reveals Superior Antithrombotic Efficacy by Targeting Thromboxane A₂ Signaling over Cyclooxygenase Inhibition

不同的血栓素A₂依赖性通路调节人血小板中花生四烯酸触发的VASP在Ser239和Ser157位点的磷酸化:实时可视化显示,靶向血栓素A₂信号通路比抑制环氧合酶具有更优的抗血栓疗效

Sheu, Joen-Rong; Huang, Wei-Chieh; Chang, Chao-Chien; Hsia, Chih-Wei; Hsia, Chih-Hsuan; Jayakumar, Thanasekaran; Hou, Shaw-Min

A Novel KGD-Based αIIbβ3 Antagonist Prevents Arterial Thrombosis While Preserving Hemostasis and Avoiding Thrombocytopenia

一种新型的基于KGD的αIIbβ3拮抗剂可预防动脉血栓形成,同时保持止血功能并避免血小板减少症。

Kuo, Yu-Ju; Chung, Ching-Hu; Chen, Chun-Chao; Liu, Ju-Chi; Chiou, Kuan-Rau; Sheu, Joen-Rong; Chuang, Woei-Jer; Huang, Tur-Fu

Verapamil Suppresses the Development of Resistance Against Anti-Tuberculosis Drugs in Mycobacteria

维拉帕米抑制结核分枝杆菌对结核病药物产生耐药性

Liu, Kunna; Buitenhek, Elise; Kuijl, Coenraad P; Mulla, Yuval; Luirink, Joen; Bald, Dirk

Lipopolysaccharide Potentiates Platelet Aggregation in Association with Apoptosis Through a Novel TLR4-Bax/Bcl-2-Mitochondrial Dysfunction Axis in Humans

脂多糖通过新型TLR4-Bax/Bcl-2-线粒体功能障碍轴增强血小板聚集并促进细胞凋亡

Chen, Chun-Chao; Hsia, Chih-Wei; Huang, Wei-Chieh; Chang, Chao-Chien; Darmanto, Arief Gunawan; Sheu, Joen-Rong

Overproduction of β-barrel outer membrane proteins in Escherichia coli BL21(DE3) induces hypervesiculation

大肠杆菌BL21(DE3)中β桶状外膜蛋白的过量表达会诱导过度囊泡形成

Sahu, Saloni; Koningstein, Gregory; Bunduc, Catalin M; van der Wel, Nicole; Luirink, Joen; van Ulsen, Peter

An Rcs Stress-Based High-Throughput Screen Reveals Novel Gyrase Inhibitors as Indirect Inducers of Cell Envelope Stress in Gram-Negative Bacteria

基于RCS应激的高通量筛选揭示新型DNA促旋酶抑制剂作为革兰氏阴性细菌细胞包膜应激的间接诱导剂

Cleenewerk, Laurence; Otto, Alexandra; Wouters, Willemijn; Willemse, Joost; Gao, Meiling; Lysenko, Vladyslav; Punt, Jeroen M; van der Stelt, Mario; Martin, Nathaniel I; van Ulsen, Peter; Luirink, Joen

Impact of expression systems on the transcriptome of Bacillus subtilis: insights for enhanced production of glutaminase PrgA

表达系统对枯草芽孢杆菌转录组的影响:提高谷氨酰胺酶 PrgA 产量的启示

Kes, Mariah B M J; Wang, Biwen; Luirink, Joen; Hamoen, Leendert W

Assessing the strengths, weaknesses, opportunities, and challenges of health camps conducted in rural areas of Dehradun, Uttarakhand: A mixed-method study

评估在北阿坎德邦德拉敦农村地区开展的健康营的优势、劣势、机遇和挑战:一项混合方法研究

Mishra, Ashutosh; Singh, Meghna; Mathew, Joen R; Singh, Mahendra; Saxena, Vartika

Pheochromocytoma: A rare cause of abdominal pain identified in a family medicine outpatient department setting

嗜铬细胞瘤:一种在家庭医学门诊部发现的罕见腹痛病因。

Teja, Srk; Aravindan, Nisarg; Ajith, Athulya V; Sachdeva, Aakash; Mathew, Joen; Kumar, Santosh