日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Rapid DNA cleavage by the LINE-1 endonuclease proximal to DNA ends and at mismatches

LINE-1核酸内切酶在DNA末端附近和错配处快速切割DNA

Miller, Bryant D; Smail, Benedict A; Van Eeuwen, Trevor; Kodama, Hanna; Kondo, Kazuma; Jiang, Hua; O'Brien, Allison; Dai, Nan; Trachman, Robert J 3rd; Guan, Shengxi; Karlow, Jennifer A; Cheng, Wen-Chih; Sedivy, John M; Jogl, Gerwald; Rout, Michael P; LaCava, John; Burns, Kathleen H; Taylor, Martin S

Orthosteric and allosteric effects of anti-CRISPR II-C1 inhibition on Geo Cas9 from integrated structural biophysics

整合结构生物物理学研究抗CRISPR II-C1抑制剂对Geo Cas9的正构和变构效应

Knight, Alexa L; Belato, Helen B; Dresser, Charlotte S; Pindi, Chinmai; Mercado, Briana J; Lasekan, Praise; Luo, Jinping; Arantes, Pablo R; Jogl, Gerwald; Palermo, Giulia; Lisi, George P

Structural and dynamic impacts of single-atom disruptions to guide RNA interactions within the recognition lobe of Geobacillus stearothermophilus Cas9

单原子破坏对嗜热芽孢杆菌Cas9识别叶内RNA相互作用的结构和动态影响

Belato, Helen B; Knight, Alexa L; D'Ordine, Alexandra M; Pindi, Chinmai; Fan, Zhiqiang; Luo, Jinping; Palermo, Giulia; Jogl, Gerwald; Lisi, George P

Structural and Dynamic Impacts of Single-atom Disruptions to Guide RNA Interactions within the Recognition Lobe of Geobacillus stearothermophilus Cas9

单原子破坏对嗜热芽孢杆菌Cas9识别叶内RNA相互作用的结构和动态影响

Belato, Helen B; Knight, Alexa L; D'Ordine, Alexandra M; Pindi, Chinmai; Fan, Zhiqiang; Luo, Jinping; Palermo, Giulia; Jogl, Gerwald; Lisi, George P

Identification and characterization of small molecule inhibitors of the LINE-1 retrotransposon endonuclease

LINE-1 逆转座子内切酶小分子抑制剂的鉴定和特性

Alexandra M D'Ordine, Gerwald Jogl, John M Sedivy

High-fidelity, hyper-accurate, and evolved mutants rewire atomic-level communication in CRISPR-Cas9

高保真、超精确和进化的突变体重新连接 CRISPR-Cas9 中的原子级通信

Erin Skeens, Souvik Sinha, Mohd Ahsan, Alexandra M D'Ordine, Gerwald Jogl, Giulia Palermo, George P Lisi

Activation of human RNA lariat debranching enzyme Dbr1 by binding protein TTDN1 occurs though an intrinsically disordered C-terminal domain

人类 RNA 套索脱支酶 Dbr1 被结合蛋白 TTDN1 激活,尽管 C 末端结构域本身无序

Nathaniel E Clark, Adam Katolik, Pascal Gallant, Anastasia Welch, Eileen Murphy, Luke Buerer, Christoph Schorl, Nandita Naik, Mandar T Naik, Stephen P Holloway, Kristin Cano, Susan T Weintraub, Katherine M Howard, P John Hart, Gerwald Jogl, Masad J Damha, William G Fairbrother

Experimental Investigation of Cohesion between UHPC and NSC Utilising Interface Protrusions

利用界面凸起对超高性能混凝土与普通混凝土之间的内聚力进行实验研究

Horák, Pavel; Pešková, Šárka; Jogl, Marcel; Sovják, Radoslav; Vítek, Petr

Disruption of electrostatic contacts in the HNH nuclease from a thermophilic Cas9 rewires allosteric motions and enhances high-temperature DNA cleavage

嗜热Cas9破坏HNH核酸酶中的静电接触,重塑变构运动,增强高温下DNA的切割能力。

Belato, Helen B; Norbrun, Carmelissa; Luo, Jinping; Pindi, Chinmai; Sinha, Souvik; D'Ordine, Alexandra M; Jogl, Gerwald; Palermo, Giulia; Lisi, George P

Structural and dynamic insights into the HNH nuclease of divergent Cas9 species

对不同 Cas9 物种的 HNH 核酸酶的结构和动力学见解

Belato, Helen B; D'Ordine, Alexandra M; Nierzwicki, Lukasz; Arantes, Pablo R; Jogl, Gerwald; Palermo, Giulia; Lisi, George P