日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX

放射治疗引起的神经认知障碍是由早期生命阶段细胞凋亡启动增强所致,而阻断 BAX 可预防这种障碍。

Rumani Singh ,Stacey Yu ,Marwa Osman ,Zintis Inde ,Cameron Fraser ,Abigail H Cleveland ,Nicole Almanzar ,Chuan Bian Lim ,Gaurav N Joshi ,Johan Spetz ,Xingping Qin ,Sneh M Toprani ,Zachary Nagel ,Matthew C Hocking ,Robert A Cormack ,Torunn I Yock ,Jeffrey W Miller ,Zhi-Min Yuan ,Timothy Gershon ,Kristopher A Sarosiek

Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 severity

SARS-CoV-2细胞进入基因和细胞死亡程序的年龄依赖性调控与COVID-19的严重程度相关。

Zintis Inde ,Ben A Croker ,Clarence Yapp ,Gaurav N Joshi ,Johan Spetz ,Cameron Fraser ,Xingping Qin ,Le Xu ,Brian Deskin ,Elisa Ghelfi ,Gabrielle Webb ,Aaron F Carlin ,Yanfang Peipei Zhu ,Sandra L Leibel ,Aaron F Garretson ,Alex E Clark ,Jason M Duran ,Victor Pretorius ,Laura E Crotty-Alexander ,Chendi Li ,Jamie Casey Lee ,Chhinder Sodhi ,David J Hackam ,Xin Sun ,Aaron N Hata ,Lester Kobzik ,Jeffrey Miller ,Jin-Ah Park ,Douglas Brownfield ,Hongpeng Jia ,Kristopher A Sarosiek

Neuroblastoma xenograft models demonstrate the therapeutic potential of 177Lu-octreotate

神经母细胞瘤异种移植模型证明了 177Lu-奥曲肽的治疗潜力

Arman Romiani, Johan Spetz, Emman Shubbar, Dan E Lind, Bengt Hallberg, Ruth H Palmer, Eva Forssell-Aronsson

Metabolic perturbations sensitize triple-negative breast cancers to apoptosis induced by BH3 mimetics

代谢扰动使三阴性乳腺癌对 BH3 类似物诱导的细胞凋亡敏感

Veerle W Daniels, Jason J Zoeller, Nick van Gastel, Kelley E McQueeney, Salma Parvin, Danielle S Potter, Geoffrey G Fell, Vinícius G Ferreira, Binyam Yilma, Rajat Gupta, Johan Spetz, Patrick D Bhola, Jennifer E Endress, Isaac S Harris, Emanuel Carrilho, Kristopher A Sarosiek, David T Scadden, Joan S

Long-term transcriptomic and proteomic effects in Sprague Dawley rat thyroid and plasma after internal low dose 131I exposure

内部低剂量 131I 暴露对 Sprague Dawley 大鼠甲状腺和血浆的长期转录组和蛋白质组学影响

Malin Larsson, Nils Rudqvist, Johan Spetz, Emman Shubbar, Toshima Z Parris, Britta Langen, Khalil Helou, Eva Forssell-Aronsson

Increased therapeutic effect on medullary thyroid cancer using a combination of radiation and tyrosine kinase inhibitors

放射线和酪氨酸激酶抑制剂联合使用可增强对髓样甲状腺癌的治疗效果

Viktor Sandblom, Johan Spetz, Emman Shubbar, Mikael Montelius, Ingun Ståhl, John Swanpalmer, Ola Nilsson, Eva Forssell-Aronsson

Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 disease severity

SARS-CoV-2 细胞进入基因和细胞死亡程序的年龄依赖性调控与 COVID-19 疾病严重程度相关

Zintis Inde, Clarence Yapp, Gaurav N Joshi, Johan Spetz, Cameron Fraser, Brian Deskin, Elisa Ghelfi, Chhinder Sodhi, David J Hackam, Lester Kobzik, Ben A Croker, Douglas Brownfield, Hongpeng Jia, Kristopher A Sarosiek

Gemcitabine potentiates the anti-tumour effect of radiation on medullary thyroid cancer

吉西他滨增强放射治疗髓样甲状腺癌的抗肿瘤作用

Viktor Sandblom, Johan Spetz, Emman Shubbar, Mikael Montelius, Ingun Ståhl, John Swanpalmer, Ola Nilsson, Eva Forssell-Aronsson

Identification of Potential MR-Derived Biomarkers for Tumor Tissue Response to 177Lu-Octreotate Therapy in an Animal Model of Small Intestine Neuroendocrine Tumor

在小肠神经内分泌肿瘤动物模型中鉴定肿瘤组织对 177Lu-奥曲肽治疗反应的潜在 MR 衍生生物标志物

Mikael Montelius, Johan Spetz, Oscar Jalnefjord, Evelin Berger, Ola Nilsson, Maria Ljungberg, Eva Forssell-Aronsson

Hedgehog inhibitor sonidegib potentiates 177Lu-octreotate therapy of GOT1 human small intestine neuroendocrine tumors in nude mice

Hedgehog 抑制剂 sonidegib 增强 177Lu-奥曲肽对裸鼠 GOT1 人类小肠神经内分泌肿瘤的治疗作用

Johan Spetz, Britta Langen, Nils Rudqvist, Toshima Z Parris, Khalil Helou, Ola Nilsson, Eva Forssell-Aronsson