John Shinu相关文献与解析，生知库 | 链接生命科学的每一步

Leibler, Claire; Thomas, Kayla B; Josensi, Coralie; Levack, Russell C; Smita, Shuchi; John, Shinu; Wikenheiser, Daniel J; Bastacky, Sheldon; Gingras, Sebastien; Nickerson, Kevin M; Shlomchik, Mark J

TLR9

信号转导

TLR7

免疫/内分泌

发表日期：2025

文献求助收藏

Pre-existing immunity to cytomegalovirus in macaques influences human CMV vaccine responses in preclinical models.

猕猴体内已存在的巨细胞病毒免疫力会影响临床前模型中人类巨细胞病毒疫苗的反应

期刊:Vaccine

影响因子:3.5

doi:10.1016/j.vaccine.2021.08.011

Webster Helen, Valencia Sarah, Kumar Amit, Chan Cliburn, Dennis Maria, Roark Hunter, Woods Angela, John Shinu, Carfi Andrea, Permar Sallie R

B cell-intrinsic TLR9 expression is protective in murine lupus

B细胞内在TLR9表达对小鼠狼疮具有保护作用

期刊:Journal of Clinical Investigation

影响因子:13.6

doi:10.1172/JCI132328

Tilstra, Jeremy S; John, Shinu; Gordon, Rachael A; Leibler, Claire; Kashgarian, Michael; Bastacky, Sheldon; Nickerson, Kevin M; Shlomchik, Mark J

Sequential Activation of Two Pathogen-Sensing Pathways Required for Type I Interferon Expression and Resistance to an Acute DNA Virus Infection

两种病原体感知通路的顺序激活是I型干扰素表达和抵抗急性DNA病毒感染所必需的

期刊:Immunity

影响因子:26.3

doi:10.1016/j.immuni.2015.11.015

Xu, Ren-Huan; Wong, Eric B; Rubio, Daniel; Roscoe, Felicia; Ma, Xueying; Nair, Savita; Remakus, Sanda; Schwendener, Reto; John, Shinu; Shlomchik, Mark; Sigal, Luis J

Requirement for Transcription Factor Ets1 in B Cell Tolerance to Self-Antigens

B细胞对自身抗原的耐受性需要转录因子Ets1

期刊:Journal of Immunology

影响因子:3.4

doi:10.4049/jimmunol.1500776

Russell, Lisa; John, Shinu; Cullen, Jaime; Luo, Wei; Shlomchik, Mark J; Garrett-Sinha, Lee Ann

Transcription factor Ets1, but not the closely related factor Ets2, inhibits antibody-secreting cell differentiation

转录因子Ets1（而非与其密切相关的因子Ets2）抑制抗体分泌细胞分化。

期刊:Molecular and Cellular Biology

影响因子:2.7

doi:10.1128/MCB.00612-13

John, Shinu; Russell, Lisa; Chin, Shu Shien; Luo, Wei; Oshima, Robert; Garrett-Sinha, Lee Ann

细胞生物学

发表日期：2014

文献求助收藏

Divergent TIR signaling domains in TLR7 and TLR9 control opposing effects on systemic autoimmunity

TLR7和TLR9中不同的TIR信号域对系统性自身免疫产生相反的作用

Pre-existing immunity to cytomegalovirus in macaques influences human CMV vaccine responses in preclinical models.

猕猴体内已存在的巨细胞病毒免疫力会影响临床前模型中人类巨细胞病毒疫苗的反应

B cell-intrinsic TLR9 expression is protective in murine lupus

B细胞内在TLR9表达对小鼠狼疮具有保护作用

Sequential Activation of Two Pathogen-Sensing Pathways Required for Type I Interferon Expression and Resistance to an Acute DNA Virus Infection

两种病原体感知通路的顺序激活是I型干扰素表达和抵抗急性DNA病毒感染所必需的

Requirement for Transcription Factor Ets1 in B Cell Tolerance to Self-Antigens

B细胞对自身抗原的耐受性需要转录因子Ets1

Transcription factor Ets1, but not the closely related factor Ets2, inhibits antibody-secreting cell differentiation

转录因子Ets1（而非与其密切相关的因子Ets2）抑制抗体分泌细胞分化。