日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Resident tissue macrophages maintain intraocular pressure homeostasis.

驻留组织巨噬细胞维持眼内压稳态。

Liu Katy C, Grimsrud Aleksander O, Suarez Maria Fernanda, Schuman Darren, De Ieso Michael L, Kuhn Megan, Kelly Ruth A, Mathew Rose, Kalnitsky Joan, Mack Matthias, Anagnostopoulos Gerasimos, Ginhoux Florent, Bupp-Chickering Violet, Balasubramanian Revathi, John Simon W M, Stamer W Daniel, Saban Daniel R

Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatment.

对小梁网进行单细胞分析,发现青光眼模型中存在线粒体功能障碍,而维生素 B3 治疗可以保护这种功能障碍。

Tolman Nicholas, Li Taibo, Balasubramanian Revathi, Li Guorong, Pfeiffer Rebecca, Bupp-Chickering Violet, Kelly Ruth A, Simón Marina, Peregrin John, Montgomery Christa, Jones Bryan, Stamer W Daniel, Qian Jiang, John Simon W M

MKK4 and MKK7 control degeneration of retinal ganglion cell somas and axons after glaucoma-relevant injury.

MKK4 和 MKK7 控制青光眼相关损伤后视网膜神经节细胞胞体和轴突的退化。

Marola Olivia J, Syc-Mazurek Stephanie B, Yablonski Sarah E R, Shrager Peter G, John Simon W M, Libby Richard T

Pyruvate and related energetic metabolites modulate resilience against high genetic risk for glaucoma

丙酮酸及相关高能代谢物调节机体对青光眼高遗传风险的抵抗力

Li, Keva; Tolman, Nicholas; Segrè, Ayellet V; Stuart, Kelsey V; Zeleznik, Oana A; Vallabh, Neeru A; Hu, Kuang; Zebardast, Nazlee; Hanyuda, Akiko; Raita, Yoshihiko; Montgomery, Christa; Zhang, Chi; Hysi, Pirro G; Do, Ron; Khawaja, Anthony P; Wiggs, Janey L; Kang, Jae H; John, Simon W M; Pasquale, Louis R

In Vivo Quantification of Anterior and Posterior Chamber Volumes in Mice: Implications for Aqueous Humor Dynamics

小鼠前房和后房容积的体内定量分析:对房水动力学的启示

Kim, Daniel; Fang, Raymond; Zhang, Pengpeng; Yan, Zihang; Sun, Cheng; Li, Guorong; Montgomery, Christa; John, Simon W M; Stamer, W Daniel; Zhang, Hao F; Ethier, C Ross

Absence of Glaucoma in Tg-MYOCY437H Mice of Diverse Genetic Backgrounds

具有不同遗传背景的Tg-MYOCY437H小鼠均未出现青光眼

Tolman, Nicholas G; Simón, Marina; Juarez, Felicia A; Zhang, Chi; Hristova, Zhivka I; Ouellette, Tionna B; Sellarole, Michael A; deVries, Wilhelmine N; Montgomery, Christa; John, Simon W M

TLR4 deficiency does not alter glaucomatous progression in a mouse model of chronic glaucoma

在慢性青光眼小鼠模型中,TLR4缺陷并不改变青光眼的进展。

Zhang, Chi; Simón, Marina; Harder, Jeffrey M; Lim, Haeyn; Montgomery, Christa; Wang, Qing; John, Simon W M

Resident Tissue Macrophages Govern Intraocular Pressure Homeostasis

驻留组织巨噬细胞调控眼内压稳态

Liu, Katy C; Grimsrud, Aleksander O; Suarez, Maria Fernanda; Schuman, Darren; De Ieso, Michael L; Kuhn, Megan; Kelly, Ruth A; Mathew, Rose; Kalnitsky, Joan; Mack, Matthias; Ginhoux, Florent; Bupp-Chickering, Violet; Balasubramanian, Revathi; John, Simon W M; Stamer, W Daniel; Saban, Daniel R

Single-Cell Characterization of Anterior Segment Development: Cell Types, Pathways, and Signals Driving Formation of the Trabecular Meshwork and Schlemm's Canal

前段发育的单细胞表征:驱动小梁网和施莱姆氏管形成的细胞类型、通路和信号

Balasubramanian, Revathi; Tolman, Nicholas; Li, Taibo; Hannan, Abdul; Bupp-Chickering, Violet; Polanco, Karina; Bhandari, Aakriti; Zhou, Sally; Simón, Marina; Peregrin, John; Montgomery, Christa; Kizhatil, Krishnakumar; Qian, Jiang; John, Simon W M

Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatment

对小梁网进行单细胞分析发现,在维生素B3治疗可保护青光眼模型中存在线粒体功能障碍。

Tolman, Nicholas; Li, Taibo; Balasubramanian, Revathi; Li, Guorong; Pfeiffer, Rebecca; Bupp-Chickering, Violet; Kelly, Ruth A; Simón, Marina; Peregrin, John; Montgomery, Christa; Jones, Bryan; Stamer, W Daniel; Qian, Jiang; John, Simon W M