日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Formation of CYP3A-specific metabolites of ibrutinib in vitro is correlated with hepatic CYP3A activity and 4β-hydroxycholesterol/cholesterol ratio

体外伊布替尼 CYP3A 特异性代谢物的形成与肝脏 CYP3A 活性和 4β-羟基胆固醇/胆固醇比率相关

Jonghwa Lee, John K Fallon, Philip C Smith, Klarissa D Jackson

Using Extracellular Vesicles Released by GDNF-Transfected Macrophages for Therapy of Parkinson Disease

利用 GDNF 转染巨噬细胞释放的细胞外囊泡治疗帕金森病

Yuling Zhao, Matthew J Haney, John K Fallon, Myosotys Rodriguez, Carson J Swain, Camryn J Arzt, Philip C Smith, Matthew Shane Loop, Emily B Harrison, Nazira El-Hage, Elena V Batrakova

A novel differentiated HuH-7 cell model to examine bile acid metabolism, transport and cholestatic hepatotoxicity

一种新型分化型 HuH-7 细胞模型,用于研究胆汁酸代谢、运输和胆汁淤积性肝毒性

Chitra Saran, Dong Fu, Henry Ho, Abigail Klein, John K Fallon, Paavo Honkakoski, Kim L R Brouwer

A phase I evaluation of the effect of curcumin on dose-limiting toxicity and pharmacokinetics of irinotecan in participants with solid tumors

姜黄素对实体肿瘤患者伊立替康剂量限制性毒性和药代动力学影响的 I 期评估

Olumide B Gbolahan, Bert H O'Neil, Autumn J McRee, Hanna K Sanoff, John K Fallon, Philip C Smith, Anastasia Ivanova, Dominic T Moore, Julie Dumond, Gary N Asher

Extracellular Vesicles as Drug Delivery System for Treatment of Neurodegenerative Disorders: Optimization of the Cell Source

细胞外囊泡作为治疗神经退行性疾病的药物输送系统:细胞来源的优化

Matthew J Haney, Yuling Zhao, John K Fallon, Wang Yue, Samuel M Li, Emily E Lentz, Dorothy Erie, Philip C Smith, Elena V Batrakova

Endogenous Coproporphyrin I and III are Altered in Multidrug Resistance-Associated Protein 2-Deficient (TR-) Rats

内源性粪卟啉 I 和 III 在多药耐药相关蛋白 2 缺陷 (TR-) 大鼠中发生改变

Jacqueline Bezençon, Chitra Saran, Janine Hussner, James J Beaudoin, Yueping Zhang, Hong Shen, John K Fallon, Philip C Smith, Henriette E Meyer Zu Schwabedissen, Kim L R Brouwer

Carboxylesterase Activities and Protein Expression in Rabbit and Pig Ocular Tissues

兔和猪眼组织中的羧酸酯酶活性和蛋白质表达

Anam Hammid, John K Fallon, Toni Lassila, Giulia Salluce, Philip C Smith, Ari Tolonen, Achim Sauer, Arto Urtti, Paavo Honkakoski

Role of Organic Solute Transporter Alpha/Beta in Hepatotoxic Bile Acid Transport and Drug Interactions

有机溶质转运蛋白 α/β 在肝毒性胆汁酸转运和药物相互作用中的作用

James J Beaudoin, Jacqueline Bezençon, Noora Sjöstedt, John K Fallon, Kim L R Brouwer

Evaluation of human primary intestinal monolayers for drug metabolizing capabilities

人类原代肠单层细胞药物代谢能力的评估

Jennifer E Speer, Yuli Wang, John K Fallon, Philip C Smith, Nancy L Allbritton

Molecular transport through primary human small intestinal monolayers by culture on a collagen scaffold with a gradient of chemical cross-linking

通过在具有化学交联梯度的胶原支架上培养,分子通过原代人类小肠单层细胞进行运输

Jennifer E Speer, Dulan B Gunasekara, Yuli Wang, John K Fallon, Peter J Attayek, Philip C Smith, Christopher E Sims, Nancy L Allbritton