Anti-ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1
抗ACVR1抗体通过激活进行性骨化性纤维发育不良(FOP)突变型ACVR1,加剧FOP中的异位骨化。
期刊:Journal of Clinical Investigation
影响因子:13.3
doi:10.1172/JCI153792
Senem Aykul,Lily Huang,Lili Wang,Nanditha M Das,Sandra Reisman,Yonaton Ray,Qian Zhang,Nyanza Rothman,Kalyan C Nannuru,Vishal Kamat,Susannah Brydges,Luca Troncone,Laura Johnsen,Paul B Yu,Sergio Fazio,John Lees-Shepard,Kevin Schutz,Andrew J Murphy,Aris N Economides,Vincent Idone,Sarah J Hatsell