文献库，生知库 | 链接生命科学的每一步

日期影响因子

Ageing and Polypharmacy in Mesenchymal Stromal Cells: Metabolic Impact Assessed by Hyperspectral Imaging of Autofluorescence

间充质基质细胞的衰老和多种药物治疗：通过自发荧光高光谱成像评估代谢影响

期刊:International Journal of Molecular Sciences

影响因子:0.7

doi:10.3390/ijms25115830

Chandrasekara M N Chandrasekara, Gizem Gemikonakli, John Mach, Rui Sang, Ayad G Anwer, Adnan Agha, Ewa M Goldys, Sarah N Hilmer, Jared M Campbell

发表日期：2024

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Elucidating the mechanisms by which disulfiram protects against obesity and metabolic syndrome

阐明双硫仑预防肥胖和代谢综合征的机制

期刊:npj Aging and Mechanisms of Disease

影响因子:5.4

doi:10.1038/s41514-020-0046-6

Michel Bernier, Dylan Harney, Yen Chin Koay, Antonio Diaz, Abhishek Singh, Devin Wahl, Tamara Pulpitel, Ahmed Ali, Vince Guiterrez, Sarah J Mitchell, Eun-Young Kim, John Mach, Nathan L Price, Miguel A Aon, David G LeCouteur, Victoria C Cogger, Carlos Fernandez-Hernando, John O'Sullivan, Mark Larance

发表日期：2020

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Leveraging a Low-Affinity Diazaspiro Orthosteric Fragment to Reduce Dopamine D(3) Receptor (D(3)R) Ligand Promiscuity across Highly Conserved Aminergic G-Protein-Coupled Receptors (GPCRs)

利用低亲和力二氮螺环正构片段降低多巴胺D(3)受体(D(3)R)配体在高度保守的胺能G蛋白偶联受体(GPCR)中的混杂性

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.9b00412

Reilly, Sean W; Riad, Aladdin A; Hsieh, Chia-Ju; Sahlholm, Kristoffer; Jacome, Daniel A; Griffin, Suzy; Taylor, Michelle; Weng, Chi-Chang; Xu, Kuiying; Kirschner, Nathan; Luedtke, Robert R; Parry, Christopher; Malhotra, Shipra; Karanicolas, John; Mach, Robert H

GPCR/Calcium/cAMP

发表日期：2019

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Acetaminophen hepatotoxicity in mice: Effect of age, frailty and exposure type

小鼠对乙酰氨基酚的肝毒性：年龄、虚弱和暴露类型的影响

期刊:Experimental Gerontology

影响因子:3.3

doi:10.1016/j.exger.2015.11.013

Alice E Kane, Sarah J Mitchell, John Mach, Aniko Huizer-Pajkos, Catriona McKenzie, Brett Jones, Victoria Cogger, David G Le Couteur, Rafael de Cabo, Sarah N Hilmer

发表日期：2016

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N-Acetyl cysteine does not prevent liver toxicity from chronic low-dose plus subacute high-dose paracetamol exposure in young or old mice

N-乙酰半胱氨酸不能预防年轻或老年小鼠长期低剂量和亚急性高剂量对乙酰氨基酚暴露引起的肝毒性

期刊:Fundamental & Clinical Pharmacology

影响因子:2.1

doi:10.1111/fcp.12184

Alice Elizabeth Kane, Aniko Huizer-Pajkos, John Mach, Catriona McKenzie, Sarah Jayne Mitchell, Rafael de Cabo, Brett Jones, Victoria Cogger, David G Le Couteur, Sarah Nicole Hilmer

发表日期：2016

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The effect of aging on mitochondrial and cytosolic hepatic intrinsic death pathway and apoptosis associated proteins in Fischer 344 rats

衰老对Fischer 344大鼠肝细胞内线粒体和细胞浆内源性死亡途径及凋亡相关蛋白的影响

期刊:Experimental Gerontology

影响因子:3.3

doi:10.1016/j.exger.2015.04.009

John Mach, Aniko Huizer-Pajkos, Alice Kane, Brett Jones, Catriona McKenzie, Sarah J Mitchell, Rafael de Cabo, Victoria C Cogger, David G Le Couteur, Sarah N Hilmer

细胞生物学

发表日期：2015

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The effect of aging on acetaminophen pharmacokinetics, toxicity and Nrf2 in Fischer 344 rats

衰老对 Fischer 344 大鼠对乙酰氨基酚药代动力学、毒性和 Nrf2 的影响

期刊:Journals of Gerontology Series A-Biological Sciences and Medical Sciences

影响因子:4.3

doi:10.1093/gerona/glt095

John Mach, Aniko Huizer-Pajkos, Victoria C Cogger, Catriona McKenzie, David G Le Couteur, Brett E Jones, Rafael de Cabo, Sarah N Hilmer

细胞生物学

发表日期：2014

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