日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pharmacologic improvement of CFTR function rapidly decreases sputum pathogen density, but lung infections generally persist

药物改善 CFTR 功能可迅速降低痰液病原体密度,但肺部感染通常会持续存在

David P Nichols, Sarah J Morgan, Michelle Skalland, Anh T Vo, Jill M Van Dalfsen, Sachinkumar Bp Singh, Wendy Ni, Lucas R Hoffman, Kailee McGeer, Sonya L Heltshe, John P Clancy, Steven M Rowe, Peter Jorth, Pradeep K Singh; PROMISE-Micro Study Group

CFTR dysfunction in smooth muscle drives TGFβ dependent airway hyperreactivity

平滑肌中的 CFTR 功能障碍导致 TGFβ 依赖性气道高反应性

Elizabeth L Kramer, Kristin M Hudock, Cynthia R Davidson, John P Clancy

Phenotypic Alteration of an Established Human Airway Cell Line by Media Selection

通过培养基选择对已建立的人类气道细胞系进行表型改变

Galit Livnat, Jessica D Meeker, Alicia J Ostmann, Lauren M Strecker, John P Clancy, John J Brewington

Patient personalized translational tools in cystic fibrosis to transform data from bench to bed-side and back

囊性纤维化患者个性化转化工具,将数据从实验室转移到临床,再从临床转移到患者

Kavisha Arora, Fanmuyi Yang, John Brewington, Gary McPhail, Alexander R Cortez, Nambirajan Sundaram, Yashaswini Ramananda, Herbert Ogden, Michael Helmrath, John P Clancy, Anjaparavanda P Naren

Fibrocyte accumulation in the lungs of cystic fibrosis patients

囊性纤维化患者肺内的纤维细胞积聚

Rajesh K Kasam, Prathibha R Gajjala, Anil G Jegga, Jennifer A Courtney, Scott H Randell, Elizabeth L Kramer, John P Clancy, Satish K Madala

CRISPRi-mediated functional analysis of lung disease-associated loci at non-coding regions

CRISPRi 介导的非编码区肺病相关基因位点功能分析

William D Stuart, Minzhe Guo, Iris M Fink-Baldauf, Alan M Coleman, John P Clancy, Marcus A Mall, Foong-Yen Lim, John J Brewington, Yutaka Maeda

Clinically-approved CFTR modulators rescue Nrf2 dysfunction in cystic fibrosis airway epithelia

临床批准的 CFTR 调节剂可挽救囊性纤维化气道上皮中的 Nrf2 功能障碍

Dana C Borcherding, Matthew E Siefert, Songbai Lin, John Brewington, Hesham Sadek, John P Clancy, Scott M Plafker, Assem G Ziady

Direct Lung Sampling Indicates That Established Pathogens Dominate Early Infections in Children with Cystic Fibrosis

直接肺取样表明,已确定的病原体在囊性纤维化患儿的早期感染中占主导地位

Peter Jorth, Zarmina Ehsan, Amir Rezayat, Ellen Caldwell, Christopher Pope, John J Brewington, Christopher H Goss, Dan Benscoter, John P Clancy, Pradeep K Singh

Brushed nasal epithelial cells are a surrogate for bronchial epithelial CFTR studies

刷状鼻上皮细胞可作为支气管上皮 CFTR 研究的替代物

John J Brewington, Erin T Filbrandt, F J LaRosa 3rd, Jessica D Moncivaiz, Alicia J Ostmann, Lauren M Strecker, John P Clancy

Chronic β2AR stimulation limits CFTR activation in human airway epithelia

慢性 β2AR 刺激限制了人类气道上皮细胞中的 CFTR 激活

John J Brewington, Jessica Backstrom, Amanda Feldman, Elizabeth L Kramer, Jessica D Moncivaiz, Alicia J Ostmann, Xiaoting Zhu, L Jason Lu, John P Clancy