日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PD-L1- and IL-4-expressing basophils promote pathogenic accumulation of T follicular helper cells in lupus

PD-L1 和 IL-4 表达的嗜碱性粒细胞促进狼疮中 T 滤泡辅助细胞的致病性积聚

John Tchen #, Quentin Simon #, Léa Chapart, Morgane K Thaminy, Shamila Vibhushan, Loredana Saveanu, Yasmine Lamri, Fanny Saidoune, Emeline Pacreau, Christophe Pellefigues, Julie Bex-Coudrat, Hajime Karasuyama, Kensuke Miyake, Juan Hidalgo, Padraic G Fallon, Thomas Papo, Ulrich Blank, Marc Benhamou, 

AMG853, A Bispecific Prostaglandin D2 Receptor 1 and 2 Antagonist, Dampens Basophil Activation and Related Lupus-Like Nephritis Activity in Lyn-Deficient Mice

AMG853 是一种双特异性前列腺素 D2 受体 1 和 2 拮抗剂,可抑制 Lyn 缺乏小鼠的嗜碱性粒细胞活化和相关的狼疮样肾炎活动

Christophe Pellefigues, John Tchen, Chaimae Saji, Yasmine Lamri, Nicolas Charles

CT-M8 Mice: A New Mouse Model Demonstrates That Basophils Have a Nonredundant Role in Lupus-Like Disease Development

CT-M8 小鼠:一种新型小鼠模型证明嗜碱性粒细胞在狼疮样疾病发展中发挥非冗余作用

John Tchen, Quentin Simon, Léa Chapart, Christophe Pellefigues, Hajime Karasuyama, Kensuke Miyake, Ulrich Blank, Marc Benhamou, Eric Daugas, Nicolas Charles

A DL-4- and TNFα-based culture system to generate high numbers of nonmodified or genetically modified immunotherapeutic human T-lymphoid progenitors

基于 DL-4 和 TNFα 的培养系统可产生大量未修饰或基因修饰的免疫治疗性人类 T 淋巴祖细胞

Ranjita Devi Moirangthem #, Kuiying Ma #, Sabrina Lizot, Anne Cordesse, Juliette Olivré, Corinne de Chappedelaine, Akshay Joshi, Agata Cieslak, John Tchen, Nicolas Cagnard, Vahid Asnafi, Antonio Rausell, Laura Simons, Julien Zuber, Tom Taghon, Frank J T Staal, Françoise Pflumio, Emmanuelle Six, Mari