日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

APC and P53 mutations synergise to create a therapeutic vulnerability to NOTUM inhibition in advanced colorectal cancer

APC 和 P53 突变协同作用,使晚期结直肠癌对 NOTUM 抑制剂产生治疗敏感性。

Tian, Yuhua; Wang, Xin; Cramer, Zvi; Rhoades, Joshua; Estep, Katrina N; Ma, Xianghui; Adams-Tzivelekidis, Stephanie; Katona, Bryson W; Johnson, F Brad; Yu, Zhengquan; Blanco, M Andres; Lengner, Christopher J; Li, Ning

Do the telomere ends justify the physical means?

端粒末端是否足以证明采用物理手段的合理性?

Pignolo, Robert J; Johnson, F Brad

G-quadruplexes in fibrotic scars may open new therapeutic avenues for wound healing

纤维化瘢痕中的G-四链体可能为伤口愈合开辟新的治疗途径

Johnson, F Brad; Yatsunyk, Liliya A

Correction to: HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression

更正:HnRNPA2 是一种新型组蛋白乙酰转移酶,介导线粒体应激诱导的核基因表达

Guha, Manti; Srinivasan, Satish; Guja, Kip; Mejia, Edison; Garcia-Diaz, Miguel; Johnson, F Brad; Ruthel, Gordon; Kaufman, Brett A; Rappaport, Eric F; Glineburg, M Rebecca; Fang, Ji-Kang; Klein-Szanto, Andres J; Nakagawa, Hiroshi; Basha, Jeelan; Kundu, Tapas; Avadhani, Narayan G

Potential Roles for G-Quadruplexes in Mitochondria

G-四链体在细胞线粒体中的潜在作用

Falabella, Micol; Fernandez, Rafael J; Johnson, F Brad; Kaufman, Brett A

Epigenetic Mechanisms Impacting Aging: A Focus on Histone Levels and Telomeres

影响衰老的表观遗传机制:聚焦组蛋白水平和端粒

Song, Shufei; Johnson, F Brad

HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression

HnRNPA2是一种新型组蛋白乙酰转移酶,介导线粒体应激诱导的核基因表达。

Guha, Manti; Srinivasan, Satish; Guja, Kip; Mejia, Edison; Garcia-Diaz, Miguel; Johnson, F Brad; Ruthel, Gordon; Kaufman, Brett A; Rappaport, Eric F; Glineburg, M Rebecca; Fang, Ji-Kang; Klein-Szanto, Andres J; Klein Szanto, Andres; Nakagawa, Hiroshi; Basha, Jeelan; Kundu, Tapas; Avadhani, Narayan G

Changes in the Transcriptome of Human Astrocytes Accompanying Oxidative Stress-Induced Senescence

氧化应激诱导衰老伴随的人类星形胶质细胞转录组变化

Crowe, Elizabeth P; Tuzer, Ferit; Gregory, Brian D; Donahue, Greg; Gosai, Sager J; Cohen, Justin; Leung, Yuk Y; Yetkin, Emre; Nativio, Raffaella; Wang, Li-San; Sell, Christian; Bonini, Nancy M; Berger, Shelley L; Johnson, F Brad; Torres, Claudio

Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response

酵母Isw2染色质重塑酶的失活可通过诱导基因毒性应激反应模拟热量限制的长寿效应

Dang, Weiwei; Sutphin, George L; Dorsey, Jean A; Otte, Gabriel L; Cao, Kajia; Perry, Rocco M; Wanat, Jennifer J; Saviolaki, Dimitra; Murakami, Christopher J; Tsuchiyama, Scott; Robison, Brett; Gregory, Brian D; Vermeulen, Michiel; Shiekhattar, Ramin; Johnson, F Brad; Kennedy, Brian K; Kaeberlein, Matt; Berger, Shelley L

Association of G-quadruplex forming sequences with human mtDNA deletion breakpoints

G-四链体形成序列与人类线粒体DNA缺失断点的关联

Dong, Dawei W; Pereira, Filipe; Barrett, Steven P; Kolesar, Jill E; Cao, Kajia; Damas, Joana; Yatsunyk, Liliya A; Johnson, F Brad; Kaufman, Brett A