日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CACHD1-deficient mice exhibit hearing and balance deficits associated with a disruption of calcium homeostasis in the inner ear

CACHD1缺陷小鼠表现出听力和平衡障碍,这与内耳钙稳态紊乱有关。

Tian, Cong; Johnson, Kenneth R; Lett, Jaclynn M; Voss, Robert; Salt, Alec N; Hartsock, Jared J; Steyger, Peter S; Ohlemiller, Kevin K

Deletion of a Long-Range Dlx5 Enhancer Disrupts Inner Ear Development in Mice

删除长程Dlx5增强子会破坏小鼠内耳发育

Johnson, Kenneth R; Gagnon, Leona H; Tian, Cong; Longo-Guess, Chantal M; Low, Benjamin E; Wiles, Michael V; Kiernan, Amy E

A spontaneous mouse deletion in Mctp1 uncovers a long-range cis-regulatory region crucial for NR2F1 function during inner ear development

Mctp1基因的自发性小鼠缺失揭示了一个对NR2F1在内耳发育过程中的功能至关重要的长程顺式调控区域

Tarchini, Basile; Longo-Guess, Chantal; Tian, Cong; Tadenev, Abigail L D; Devanney, Nicholas; Johnson, Kenneth R

Hearing loss without overt metabolic acidosis in ATP6V1B1 deficient MRL mice, a new genetic model for non-syndromic deafness with enlarged vestibular aqueducts

ATP6V1B1缺陷型MRL小鼠出现无明显代谢性酸中毒的听力损失,这是一种新的非综合征性耳聋伴前庭导水管扩大的遗传模型

Tian, Cong; Gagnon, Leona H; Longo-Guess, Chantal; Korstanje, Ron; Sheehan, Susan M; Ohlemiller, Kevin K; Schrader, Angela D; Lett, Jaclynn M; Johnson, Kenneth R

N-acetyl-cysteine prevents age-related hearing loss and the progressive loss of inner hair cells in γ-glutamyl transferase 1 deficient mice.

N-乙酰半胱氨酸可预防年龄相关性听力损失和α³-谷氨酰转移酶1缺乏小鼠的内毛细胞进行性丧失

Ding Dalian, Jiang Haiyan, Chen Guang-Di, Longo-Guess Chantal, Muthaiah Vijaya Prakash Krishnan, Tian Cong, Sheppard Adam, Salvi Richard, Johnson Kenneth R

A hypomorphic mutation of the gamma-1 adaptin gene (Ap1g1) causes inner ear, retina, thyroid, and testes abnormalities in mice

γ-1适应蛋白基因(Ap1g1)的低效突变会导致小鼠出现内耳、视网膜、甲状腺和睾丸异常。

Johnson, Kenneth R; Gagnon, Leona H; Chang, Bo

Application of Mouse Models to Research in Hearing and Balance

小鼠模型在听觉和平衡研究中的应用

Ohlemiller, Kevin K; Jones, Sherri M; Johnson, Kenneth R

A QTL on Chr 5 modifies hearing loss associated with the fascin-2 variant of DBA/2J mice

位于 5 号染色体上的一个数量性状基因座 (QTL) 会影响 DBA/2J 小鼠 fascin-2 变体相关的听力损失。

Johnson, Kenneth R; Longo-Guess, Chantal M; Gagnon, Leona H

Association of a citrate synthase missense mutation with age-related hearing loss in A/J mice

柠檬酸合酶错义突变与A/J小鼠年龄相关性听力损失的关联

Johnson, Kenneth R; Gagnon, Leona H; Longo-Guess, Chantal; Kane, Kelly L

Mutations of the mouse ELMO domain containing 1 gene (Elmod1) link small GTPase signaling to actin cytoskeleton dynamics in hair cell stereocilia

小鼠 ELMO 结构域包含基因 1 (Elmod1) 的突变将小 GTP 酶信号传导与毛细胞立体纤毛中的肌动蛋白细胞骨架动力学联系起来

Johnson, Kenneth R; Longo-Guess, Chantal M; Gagnon, Leona H