日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Functional genomics identifies therapeutic options, biomarkers, and resistance mechanisms for high-grade gliomas

功能基因组学可识别高级别胶质瘤的治疗方案、生物标志物和耐药机制。

Lin, Wan-Hsin; Kosari, Farhad; Smadbeck, James B; Barrett, Michael T; Feathers, Ryan W; Hall, Jamie; Sadeghian, Dorsay; Sotiriou, Sotiris; Johnson, Sarah H; Harris, Faye R; Berry, Taylor; McCune, Alexa F; Murphy, Stephen J; Kinsella, Lindsey; Haydu, Lauren E; Moniz-Garcia, Diogo; Fortin Ensign, Shannon P; Yang, Lin; Emanuel, Angela R; Jones, Leila A; Schaefer-Klein, Janet L; Ida, Cristiane M; Salomao, Marcela A; Sherman, Wendy J; Porter, Alyx B; Rosenfeld, Steven S; Kizilbash, Sani H; Jaeckle, Kurt A; Mrugala, Maciej M; Mansfield, Aaron S; Borad, Mitesh J; Bendok, Bernard R; Burns, Terry C; Quinones-Hinojosa, Alfredo; Cheville, John C; Vasmatzis, George; Anastasiadis, Panos Z

Tumor ploidy determination in low-pass whole genome sequencing and allelic copy number visualization using the Constellation Plot

利用星座图进行低深度全基因组测序中的肿瘤倍性测定和等位基因拷贝数可视化。

Johnson, Sarah H; Smadbeck, James B; Zenka, Roman M; Barrett, Michael T; Gaitatzes, Athanasios; Solanki, Arnav; Florio, Angela B; Borad, Mitesh J; Cheville, John C; Vasmatzis, George

Functional impact of the hyperduplication genomophenotype in high copy number endometrial cancer.

高拷贝数子宫内膜癌中超重复基因表型的功能影响

Florio Angela, Smadbeck James, Johnson Sarah H, Lin Wan-Hsin, Sadeghian Dorsay, Sotiriou Sotiris, Salvatori Rebeca, Feathers Ryan W, Berry Taylor, Kinsella Lindsey, Harris Faye R, McCune Alexa F, Murphy Stephen J, Ali Mohamed F, Pezeshki Abdulmohammad, Barrett Michael T, Grcevich Leah, Capasso Ilaria, De Vitis Luigi Antonio, Schivardi Gabriella, Occhiali Tommaso, Larish Alyssa M, Weroha John, Borad Mitesh J, Cheville John, Anastasiadis Panos Z, Mariani Andrea, Vasmatzis George

Complex balanced intrachromosomal rearrangement involving PITX2 identified as a cause of Axenfeld-Rieger Syndrome.

涉及 PITX2 的复杂平衡染色体内重排被确定为 Axenfeld-Rieger 综合征的病因

Farris Joseph, Khanna Cheryl, Smadbeck James B, Johnson Sarah H, Bothun Erick, Kaplan Tyler, Hoffman Francis, Polonis Katarzyna, Oliver Gavin, Reis Linda M, Semina Elena V, Rust Laura, Hoppman Nicole L, Vasmatzis George, Marcou Cherisse A, Schimmenti Lisa A, Klee Eric W

Integration of Comprehensive Genomic Analysis and Functional Screening of Affected Molecular Pathways to Inform Cancer Therapy

整合全面的基因组分析和受影响分子通路的功能筛选,以指导癌症治疗

Vasmatzis, George; Liu, Minetta C; Reganti, Sowjanya; Feathers, Ryan W; Smadbeck, James; Johnson, Sarah H; Schaefer Klein, Janet L; Harris, Faye R; Yang, Lin; Kosari, Farhad; Murphy, Stephen J; Borad, Mitesh J; Thompson, E Aubrey; Cheville, John C; Anastasiadis, Panos Z

Shared and unique genomic structural variants of different histological components within testicular germ cell tumours identified with mate pair sequencing

利用配对末端测序技术鉴定睾丸生殖细胞肿瘤中不同组织学成分的共有和特有基因组结构变异。

Bryce, Alan H; Egan, Jan B; Smadbeck, James B; Johnson, Sarah H; Murphy, Stephen J; Harris, Faye R; Halling, Geoffrey C; Terra, Simone B S P; Cheville, John; Pagliaro, Lance; Leibovich, Brad; Costello, Brian A; Vasmatzis, George

A comparison of adult rhabdomyosarcoma and high-grade neuroendocrine carcinoma of the urinary bladder reveals novel PPP1R12A fusions in rhabdomyosarcoma

成人横纹肌肉瘤与膀胱高级别神经内分泌癌的比较揭示了横纹肌肉瘤中新的PPP1R12A融合基因

Gupta, Sounak; Sosa, Carlos P; Kosari, Farhad; Folpe, Andrew; Bhinge, Kaustubh N; Yang, Lin; Agahi, Alireza; Johnson, Sarah H; Frank, Igor; Boorjian, Stephen A; Hansel, Donna E; Al-Ahmadie, Hikmat A; Reuter, Victor E; Vasmatzis, George; Jimenez, Rafael E; Herrera-Hernandez, Loren; Cheville, John C

Mate pair sequencing improves detection of genomic abnormalities in acute myeloid leukemia

配对末端测序可提高急性髓系白血病基因组异常的检测率

Aypar, Umut; Smoley, Stephanie A; Pitel, Beth A; Pearce, Kathryn E; Zenka, Roman M; Vasmatzis, George; Johnson, Sarah H; Smadbeck, James B; Peterson, Jess F; Geiersbach, Katherine B; Van Dyke, Daniel L; Thorland, Erik C; Jenkins, Robert B; Ketterling, Rhett P; Greipp, Patricia T; Kearney, Hutton M; Hoppman, Nicole L; Baughn, Linda B

Chromoanasynthesis is a common mechanism that leads to ERBB2 amplifications in a cohort of early stage HER2(+) breast cancer samples

染色体合成是导致早期 HER2(+) 乳腺癌样本队列中 ERBB2 扩增的常见机制。

Vasmatzis, George; Wang, Xue; Smadbeck, James B; Murphy, Stephen J; Geiersbach, Katherine B; Johnson, Sarah H; Gaitatzes, Athanasios G; Asmann, Yan W; Kosari, Farhad; Borad, Mitesh J; Serie, Daniel J; McLaughlin, Sarah A; Kachergus, Jennifer M; Necela, Brian M; Thompson, E Aubrey

Copy number variant analysis using genome-wide mate-pair sequencing

利用全基因组配对末端测序进行拷贝数变异分析

Smadbeck, James B; Johnson, Sarah H; Smoley, Stephanie A; Gaitatzes, Athanasios; Drucker, Travis M; Zenka, Roman M; Kosari, Farhad; Murphy, Stephen J; Hoppman, Nicole; Aypar, Umut; Sukov, William R; Jenkins, Robert B; Kearney, Hutton M; Feldman, Andrew L; Vasmatzis, George