日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Efficacy evaluation of the S-adenosylhomocysteine hydrolase inhibitor MSD-914 in rhesus macaques (Macaca Mulatta) challenged with Ebola virus by the intramuscular route

对经肌肉注射途径感染埃博拉病毒的恒河猴(Macaca mulatta)进行S-腺苷高半胱氨酸水解酶抑制剂MSD-914的疗效评价

Johnston, Sara C; Ginnetti, Anthony T; Twenhafel, Nancy A; Norris, Sarah L W; Chen, Shiying; Moore, Josh L; Boyce, Christopher W; Frick, Ondraya M; Dyer, Dave N; Marsh, Donald J; Stevens, Stephen C; Knapp, Walter F; Berrier, Kerry L; Wan, Hui; Adam, Gregory C; Hartingh, Timothy J; Esham, Heather L; Fiallos, Jimmy O; Blue, Eugene L; Sifford, Willie B; Latty, Jonathan D; Mills, Harold L; Alli, Nazira A; Piper, Ashley E; Goodson, Aimee I; Meinig, J Matthew; Olsen, David B; Lieberman, Linda A; Panchal, Rekha G

An mRNA vaccine encoding the Ebola virus glycoprotein induces high neutralizing antibody titers and provides strong protection against lethal infections in mouse models

编码埃博拉病毒糖蛋白的mRNA疫苗可诱导产生高滴度的中和抗体,并在小鼠模型中提供针对致命感染的强效保护。

Stromberg, Zachary R; Silva, Elvia E; Johnston, Sara C; Johnson, Dylan M; Hall, Dominique; Adjei, Emmanuel F; Altin, John A; Abisoye-Ogunniyan, Abisola; Gollott, Travis; He, Wei; Jones, Iris K A; Kwilas, Steve; Lund, Sean J; Mead, Heather L; Nelson, Georgia A; Ouyang, Lisa; Peters, Sandra K G; Schwedler, Jennifer L; Trecazzi, Caleb Z; Turner, Matthew W; Ye, Chunyan; Bradfute, Steven B; Fischer, Nicholas O; Hooper, Jay W; Ladner, Jason T; Rasley, Amy; Negrete, Oscar A

Dose response comparison of Nipah virus strains Malaysia and Bangladesh in hamsters exposed by the intranasal or intraperitoneal route.

比较马来西亚和孟加拉国尼帕病毒株在经鼻内或腹腔途径感染仓鼠后的剂量反应

Johnston Sara C, Qiu Ju, Norris Sarah L W, Panchal Rekha, Punger Elizabeth M, Teague Melissa, Moore Joshua L, Dyer David N, Frick Ondraya M, Stevens Stephen C, Fiallos Jimmy, Mills Harold L, Blue Eugene L, Sifford Willie B, McCarson Trevor, Casselman Amanda, Latty Jonathan D, Huie Kathleen E, Adolphi Ryan, Nalca Aysegul

Delayed Disease in Cynomolgus Macaques Exposed to Ebola Virus by an Intranasal Route

食蟹猴经鼻内途径感染埃博拉病毒后出现迟发性疾病

Johnston, Sara C; Wilhelmsen, Catherine L; Shamblin, Joshua; Kimmel, Adrienne; Zelko, Justine; Wollen, Suzanne; Goff, Arthur J

Natural History of Aerosol-Induced Ebola Virus Disease in Rhesus Macaques

恒河猴气溶胶诱发埃博拉病毒病的自然史

Downs, Isaac; Johnson, Joshua C; Rossi, Franco; Dyer, David; Saunders, David L; Twenhafel, Nancy A; Esham, Heather L; Pratt, William D; Trefry, John; Zumbrun, Elizabeth; Facemire, Paul R; Johnston, Sara C; Tompkins, Erin L; Jansen, Nathan K; Honko, Anna; Cardile, Anthony P

Natural history of disease in cynomolgus monkeys exposed to Ebola virus Kikwit strain demonstrates the reliability of this non-human primate model for Ebola virus disease

食蟹猴暴露于埃博拉病毒基奎特株后,其疾病的自然史表明,这种非人灵长类动物模型是研究埃博拉病毒病的可靠模型。

Niemuth, Nancy A; Fallacara, Dawn; Triplett, Cheryl A; Tamrakar, Sanjay M; Rajbhandari, Alisha; Florence, Clint; Ward, Lucy; Griffiths, Anthony; Carrion, Ricardo Jr; Goez-Gazi, Yenny; Alfson, Kendra J; Staples, Hilary M; Brasel, Trevor; Comer, Jason E; Massey, Shane; Smith, Jeanon; Kocsis, Andrew; Lowry, Jake; Johnston, Sara C; Nalca, Aysegul; Goff, Arthur J; Shurtleff, Amy C; Pitt, Margaret L; Trefry, John; Fay, Michael P

Attenuation and efficacy of live-attenuated Rift Valley fever virus vaccine candidates in non-human primates

减毒活裂谷热病毒候选疫苗在非人灵长类动物中的减毒和有效性

Smith, Darci R; Johnston, Sara C; Piper, Ashley; Botto, Miriam; Donnelly, Ginger; Shamblin, Joshua; Albariño, César G; Hensley, Lisa E; Schmaljohn, Connie; Nichol, Stuart T; Bird, Brian H

Cytokine modulation correlates with severity of monkeypox disease in humans

细胞因子调节与人类猴痘疾病的严重程度相关

Johnston, Sara C; Johnson, Joshua C; Stonier, Spencer W; Lin, Kenny L; Kisalu, Neville K; Hensley, Lisa E; Rimoin, Anne W

Detailed analysis of the African green monkey model of Nipah virus disease

对非洲绿猴尼帕病毒病模型的详细分析

Johnston, Sara C; Briese, Thomas; Bell, Todd M; Pratt, William D; Shamblin, Joshua D; Esham, Heather L; Donnelly, Ginger C; Johnson, Joshua C; Hensley, Lisa E; Lipkin, W Ian; Honko, Anna N

Dose Response of MARV/Angola Infection in Cynomolgus Macaques following IM or Aerosol Exposure

食蟹猴肌肉注射或气溶胶暴露后马尔堡病毒/安哥拉病毒感染的剂量反应

Johnston, Sara C; Lin, Kenny L; Twenhafel, Nancy A; Raymond, Jo Lynne W; Shamblin, Joshua D; Wollen, Suzanne E; Wlazlowski, Carly B; Wilkinson, Eric R; Botto, Miriam A; Goff, Arthur J