日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Antisense oligonucleotides directed against App and Rab5 normalized endosomal Rab activity and reversed DS-AD-linked degenerative phenotypes in the Dp16 mouse model of Down syndrome.

针对 App 和 Rab5Â 的反义寡核苷酸可使内体 Rab 活性正常化,并逆转唐氏综合征 Dp16 小鼠模型中与 DS-AD 相关的退行性表型

Chen Xu-Qiao, Zuo Xinxin, Becker Ann, Mante Michael, Florio Jazmin B, Jadhav Satish G, Albay Ricardo, Johnstone Aaron, Karachentsev Dmitry, Rissman Robert, Zhao Hien, Dowdy Steven F, Mobley William C

BDNF and TRiC-inspired reagent rescue cortical synaptic deficits in a mouse model of Huntington's disease.

BDNF 和 TRiC 启发的试剂可挽救亨廷顿病小鼠模型中的皮层突触缺陷

Gu Yingli, Pope Alexander, Smith Charlene, Carmona Christopher, Johnstone Aaron, Shi Linda, Chen Xuqiao, Santos Sarai, Bacon-Brenes Claire Cecile, Shoff Thomas, Kleczko Korbin M, Frydman Judith, Thompson Leslie M, Mobley William C, Wu Chengbiao