Superoxide-mediated phosphorylation and stabilization of Mcl-1 by AKT underlie venetoclax resistance in hematologic malignancies
超氧化物介导的磷酸化和AKT对Mcl-1的稳定作用是血液系统恶性肿瘤中维奈托克耐药的根本原因。
期刊:Leukemia
影响因子:13.4
doi:10.1038/s41375-025-02694-4
Chong, Stephen J F; Lai, Jolin X H; Iskandar, Kartini; Leong, Benedict J; Wang, Chuqi; Wang, Yuhan; Guièze, Romain; Raman, Deepika; Lim, Rachel H F; Wu, Catherine J; Chng, Wee Joo; Cheung, Alice M S; Chuah, Charles; Davids, Matthew S; Pervaiz, Shazib