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Panetti, Camilla; Daetwyler, Rahel; Moncsek, Anja; Patikas, Nikolaos; Agrafiotis, Andreas; Tang, Adelynn; Andreata, Francesco; Fumagalli, Valeria; De Lima, Jean; Wen, Lifen; King, Carolyn G; Vasanthakumar, Ajithkumar; Iannacone, Matteo; Kallies, Axel; Yermanos, Alexander; Hemberg, Martin; Joller, Nicole

T细胞

信号转导

T细胞

Chronic antigen stimulation in melanoma induces T cell exhaustion and limits efficacy of T cell bispecific therapies.

黑色素瘤中的慢性抗原刺激会导致 T 细胞耗竭，并限制 T 细胞双特异性疗法的疗效

期刊:Oncoimmunology

影响因子:6.3

doi:10.1080/2162402X.2025.2526444

Hutter-Karakoc Idil, Varypataki Eleni Maria, Neelakandhan Aparna, Lang Simone, Kramar Vesna, Varol Ahmet, Simons Sasha, Richard Marine, Pincha Mudita, Venetz Dario, Sam Johannes, Joller Nicole, MÃ¼nz Christian, Umana Pablo, Klein Christian, Amann Maria

CD4 T Cells Acquire Innate Capability Upon Classical T Cell Activation

CD4 T细胞在经典T细胞活化后获得固有能力

期刊:European Journal of Immunology

影响因子:3.7

doi:10.1002/eji.70054

Yassini, Nima; Goljat, Eva; Panetti, Camilla; Rath, Matthias; Joller, Nicole

From chaos to control: Nobel insights in regulatory T cells and immune tolerance

从混乱到控制：诺贝尔奖对调节性T细胞和免疫耐受的深刻见解

期刊:Pflugers Archiv-European Journal of Physiology

影响因子:2.9

doi:10.1007/s00424-025-03140-1

Estrada Brull, Anna; Joller, Nicole

LAG-3, TIM-3, and TIGIT: Distinct functions in immune regulation

LAG-3、TIM-3 和 TIGIT：在免疫调节中发挥不同的功能

期刊:Immunity

影响因子:26.3

doi:10.1016/j.immuni.2024.01.010

Joller, Nicole; Anderson, Ana C; Kuchroo, Vijay K

TIGIT predominantly regulates the immune response via regulatory T cells

TIGIT主要通过调节性T细胞来调节免疫反应。

期刊:Journal of Clinical Investigation

影响因子:13.6

doi:10.1172/JCI183278

Kurtulus, Sema; Sakuishi, Kaori; Ngiow, Shin-Foong; Joller, Nicole; Tan, Dewar J; Teng, Michele Wl; Smyth, Mark J; Kuchroo, Vijay K; Anderson, Ana C

Moving to the Outskirts: Interplay Between Regulatory T Cells and Peripheral Tissues

向边缘转移：调节性T细胞与外周组织的相互作用

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2022.864628

Estrada Brull, Anna; Panetti, Camilla; Joller, Nicole

Nematode microRNAs can Individually Regulate Interferon Regulatory Factor 4 and mTOR in Differentiating T Helper 2 Lymphocytes and Modulate Cytokine Production in Macrophages

线虫microRNA可以单独调节分化中的T辅助细胞2淋巴细胞中的干扰素调节因子4和mTOR，并调节巨噬细胞中的细胞因子产生。

期刊:Frontiers in Molecular Biosciences

影响因子:4

doi:10.3389/fmolb.2022.909312

Soichot, Julien; Guttmann, Nathalie; Rehrauer, Hubert; Joller, Nicole; Tritten, Lucienne

Dampening antiviral immunity can protect the host

抑制抗病毒免疫力可以保护宿主。

期刊:

影响因子:

doi:10.1111/febs.15756

Panetti, Camilla; Kao, Kung-Chi; Joller, Nicole

Rapid expansion of Treg cells protects from collateral colitis following a viral trigger

病毒感染后，Treg细胞的快速扩增可保护机体免受侧支结肠炎的侵害。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-020-15309-6

Schorer, Michelle; Lambert, Katharina; Rakebrandt, Nikolas; Rost, Felix; Kao, Kung-Chi; Yermanos, Alexander; Spörri, Roman; Oderbolz, Josua; Raeber, Miro E; Keller, Christian W; Lünemann, Jan D; Rogler, Gerhard; Boyman, Onur; Oxenius, Annette; Joller, Nicole

The co-inhibitory receptor TIGIT promotes tissue-protective functions in T cells

共抑制受体TIGIT促进T细胞的组织保护功能。

Chronic antigen stimulation in melanoma induces T cell exhaustion and limits efficacy of T cell bispecific therapies.

黑色素瘤中的慢性抗原刺激会导致 T 细胞耗竭，并限制 T 细胞双特异性疗法的疗效

CD4 T Cells Acquire Innate Capability Upon Classical T Cell Activation

CD4 T细胞在经典T细胞活化后获得固有能力

From chaos to control: Nobel insights in regulatory T cells and immune tolerance

从混乱到控制：诺贝尔奖对调节性T细胞和免疫耐受的深刻见解

LAG-3, TIM-3, and TIGIT: Distinct functions in immune regulation

LAG-3、TIM-3 和 TIGIT：在免疫调节中发挥不同的功能

TIGIT predominantly regulates the immune response via regulatory T cells

TIGIT主要通过调节性T细胞来调节免疫反应。

Moving to the Outskirts: Interplay Between Regulatory T Cells and Peripheral Tissues

向边缘转移：调节性T细胞与外周组织的相互作用

Nematode microRNAs can Individually Regulate Interferon Regulatory Factor 4 and mTOR in Differentiating T Helper 2 Lymphocytes and Modulate Cytokine Production in Macrophages

线虫microRNA可以单独调节分化中的T辅助细胞2淋巴细胞中的干扰素调节因子4和mTOR，并调节巨噬细胞中的细胞因子产生。

Dampening antiviral immunity can protect the host

抑制抗病毒免疫力可以保护宿主。

Rapid expansion of Treg cells protects from collateral colitis following a viral trigger

病毒感染后，Treg细胞的快速扩增可保护机体免受侧支结肠炎的侵害。