Inhibitor of Apoptosis Proteins (IAPs) are commonly dysregulated in GIST and can be pharmacologically targeted to enhance the pro-apoptotic activity of imatinib
凋亡蛋白抑制剂 (IAP) 在胃肠道间质瘤中通常失调,可通过药理学靶向作用来增强伊马替尼的促凋亡活性
期刊:Oncotarget
影响因子:
doi:10.18632/oncotarget.9159
Johanna Falkenhorst, Susanne Grunewald, Thomas Mühlenberg, Adrian Marino-Enriquez, Anna-Carina Reis, Christopher Corless, Michael Heinrich, Jürgen Treckmann, Lars Erik Podleska, Martin Schuler, Jonathan Alfred Fletcher, Sebastian Bauer