日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Nuclear KIT induces a NFKBIB-RELA-KIT autoregulatory loop in imatinib-resistant gastrointestinal stromal tumors

核 KIT 在伊马替尼耐药胃肠道间质瘤中诱导 NFKBIB-RELA-KIT 自身调节环路

Yuan-Shuo Hsueh, Hui Hua Chang, Yan-Shen Shan, H Sunny Sun, Jonathan Alfred Fletcher, Chien-Feng Li, Li-Tzong Chen

Inhibitor of Apoptosis Proteins (IAPs) are commonly dysregulated in GIST and can be pharmacologically targeted to enhance the pro-apoptotic activity of imatinib

凋亡蛋白抑制剂 (IAP) 在胃肠道间质瘤中通常失调,可通过药理学靶向作用来增强伊马替尼的促凋亡活性

Johanna Falkenhorst, Susanne Grunewald, Thomas Mühlenberg, Adrian Marino-Enriquez, Anna-Carina Reis, Christopher Corless, Michael Heinrich, Jürgen Treckmann, Lars Erik Podleska, Martin Schuler, Jonathan Alfred Fletcher, Sebastian Bauer