Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation
KRAS 的酪氨酰磷酸化通过改变开关 I 和 II 构象来阻止 GTPase 循环
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-018-08115-8
Yoshihito Kano, Teklab Gebregiworgis, Christopher B Marshall, Nikolina Radulovich, Betty P K Poon, Jonathan St-Germain, Jonathan D Cook, Ivette Valencia-Sama, Benjamin M M Grant, Silvia Gabriela Herrera, Jinmin Miao, Brian Raught, Meredith S Irwin, Jeffrey E Lee, Jen Jen Yeh, Zhong-Yin Zhang, Ming-S
