日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Rapidly acquired HIV-1 neutralization breadth in a rhesus V2 apex knockin mouse model after a single bolus immunization

单次注射免疫后,恒河猴V2顶端敲入小鼠模型迅速获得HIV-1中和广度

Ghosh, Amrit Raj; Habib, Rumi; Mishra, Nitesh; Roark, Ryan S; Akauliya, Madhav; Albowaidey, Ali A; Allen, Joel D; Amereh, Khaled; Avillion, Gabriel; Bottermann, Maria; Liang, Bo; Chaudhary, Namit; Callaghan, Sean; Dye, Jonathan; Li, Xuduo; Ellis-Pugh, Jordan R; Roy Chowdhury, Rohan; James, Nicole E; Liu, Xiaotie; Maiorino, Laura; Villavicencio, Paula M; Nedellec, Rebecca; Oberoi, Prabhgun; Sowers, Kirsten J; Park, Younghoon; Prum, Thavaleak; Rodriguez, Linette; Ssozi, Maria; Torres, Jonathan L; Walsh, Agnes A; Warner, John E; Weldon, Stephanie R; Xu, Liling; Wiehe, Kevin; Crispin, Max; Ward, Andrew B; Nair, Usha; Hahn, Beatrice H; Burton, Dennis R; Shapiro, Lawrence; Kwong, Peter D; Irvine, Darrell J; Andrabi, Raiees; Shaw, George M; Batista, Facundo D

Combining xQTL and genome-wide association studies from diverse populations improves druggable gene discovery

结合来自不同人群的 xQTL 和全基因组关联研究,可以提高药物靶向基因的发现效率。

Lorincz-Comi, Noah; Song, Wenqiang; Chen, Xin; Paz, Isabela Rivera; Hou, Yuan; Zhou, Yadi; Xu, Jielin; Martin, William; Barnard, John; Pieper, Andrew A; Haines, Jonathan L; Chung, Mina K; Cheng, Feixiong

Genetic modifiers of APOE-ε4-associated cognitive decline

APOE-ε4相关认知衰退的遗传修饰因子

Contreras, Alex G; Walters, Skylar; Eissman, Jaclyn M; Archer, Derek B; Regelson, Alexandra N; Durant, Alaina; Clifton, Michelle; Mukherjee, Subhabrata; Lee, Michael L; Choi, Seo-Eun; Scollard, Phoebe; Trittschuh, Emily H; Mez, Jesse; Bush, William S; Kunkle, Brian W; Cruchaga, Carlos; Naj, Adam C; Gifford, Katherine A; Bilgel, Murat; Kuzma, Amanda B; Cuccaro, Michael L; Pericak-Vance, Margaret A; Farrer, Lindsay A; Wang, Li-San; Schellenberg, Gerard D; Haines, Jonathan L; Jefferson, Angela L; Kukull, Walter A; Keene, C Dirk; Saykin, Andrew J; Thompson, Paul M; Martin, Eden R; Albert, Marilyn S; Johnson, Sterling C; Engelman, Corinne D; Ferrucci, Luigi; Bennett, David A; Barnes, Lisa L; Schneider, Julie A; Sperling, Reisa A; Resnick, Susan M; Crane, Paul K; Dumitrescu, Logan; Hohman, Timothy J

IFITM3 deficiency drives SARS-CoV-2 adaptation while preserving variant-specific traits.

IFITM3 缺陷驱动 SARS-CoV-2 适应,同时保留变异株特异性特征。

Denz Parker J, Speaks Samuel, McFadden Matthew I, Cable Jana M, Aladhami Ahmed K, Papa Jonathan L, Rayner Rachael E, Rao Prerana R, Leumi Steve, Roettger Jack E, Dhariwala Miqdad O, Cormet-Boyaka Estelle, Forero Adriana, Yount Jacob S

Endogenous CD28 drives the persistent activity of CAR T cells in myeloma and lymphoma models.

内源性 CD28 驱动 CAR T 细胞在骨髓瘤和淋巴瘤模型中的持续活性。

Lieberman Mackenzie M, Tong Jason H, Odukwe Nkechi U, Chavel Colin A, Bishara Gina G, Crasti Kimberly M, Herr Megan M, Goala Payal, Purdon Terence J, Burchett Rebecca, Gillard Bryan M, Brackett Craig M, Tario Joseph D, Rosario Spencer R, McGray Aj Robert, Bramson Jonathan L, Davila Marco L, Brentjens Renier J, Malek Ehsan, Lee Kelvin P, Olejniczak Scott H

WDR12 and HIVEP3 are contributors to cognitive preservation in Amish SuperAgers

WDR12 和 HIVEP3 是阿米什超级老年人保持认知能力的因素之一。

Dorfsman, Daniel; Prough, Michael B; Gulyayev, Alex; Caywood, Laura J; Clouse, Jason E; Herington, Sharlene D; Slifer, Susan H; Adams, Larry D; Laux, Renee A; Song, Yeunjoo E; Lynn, Audrey; Fuzzell, Sarada L; Hochstetler, Sherri D; Miskimen, Kristy; Main, Leighanne R; Wang, Ping; Liu, Yining; Moore, Noel; Ogrocki, Paula; Lerner, Alan J; Vance, Jeffery M; Cuccaro, Michael L; Haines, Jonathan L; Pericak-Vance, Margaret A; Scott, William K

Evaluating the association of apolipoprotein E genotype and cognitive resilience in SuperAgers

评估载脂蛋白E基因型与超龄者认知韧性的关联

Durant, Alaina; Mukherjee, Shubhabrata; Lee, Michael L; Choi, Seo-Eun; Scollard, Phoebe; Klinedinst, Brandon S; Trittschuh, Emily H; Mez, Jesse; Farrer, Lindsay A; Gifford, Katherine A; Cruchaga, Carlos; Hassenstab, Jason; Naj, Adam C; Wang, Li-San; Johnson, Sterling C; Engelman, Corinne D; Kukull, Walter A; Keene, C Dirk; Saykin, Andrew J; Cuccaro, Michael L; Kunkle, Brian W; Pericak-Vance, Margaret A; Martin, Eden R; Bennett, David A; Barnes, Lisa L; Schneider, Julie A; Bush, William S; Haines, Jonathan L; Mayeux, Richard; Vardarajan, Badri N; Albert, Marilyn S; Thompson, Paul M; Jefferson, Angela L; Crane, Paul K; Dumitrescu, Logan; Archer, Derek B; Hohman, Timothy J; Gaynor, Leslie S

Dissecting Alzheimer's disease heritability across populations

剖析阿尔茨海默病在不同人群中的遗传性

Liu, Shiying; Bush, William S; Kunkle, Brian W; Byrd, Goldie S; Reitz, Christiane; Tosto, Giuseppe; Rajabli, Farid; Caban-Holt, Allison M; Cuccaro, Michael; Starks, Takiyah; Adams, Larry D; Feliciano, Briseida E; Akinyemi, Rufus; Vance, Jeffery M; Pericak-Vance, Margaret; Haines, Jonathan L; Crawford, Dana C; Williams, Scott M

Viral mimicry may help explain immunogenic cell death

病毒模拟可能有助于解释免疫原性细胞死亡

Levine, Matthew S; Li, Jiexi; Ehrlich, Lauren I R; DePinho, Ronald A; Iverson, Brent; Sessler, Jonathan L

Reconstruction of human metabolic models with large language models

利用大型语言模型重建人类代谢模型

Luo, Jiahao; Wang, Hao; Moyer, Devlin; Guo, Zhetao; Robinson, Jonathan L; Gustafsson, Johan; Anton, Mihail; Chen, Yu; Kerkhoven, Eduard J; Nielsen, Jens; Li, Feiran