日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ASCT2 is a major contributor to serine uptake in cancer cells

ASCT2 是癌细胞吸收丝氨酸的主要因素

Kelly O Conger, Christopher Chidley, Mete Emir Ozgurses, Huiping Zhao, Yumi Kim, Svetlana E Semina, Philippa Burns, Vipin Rawat, Lina Lietuvninkas, Ryan Sheldon, Issam Ben-Sahra, Jonna Frasor, Peter K Sorger, Gina M DeNicola, Jonathan L Coloff

ASCT2 is the primary serine transporter in cancer cells

ASCT2 是癌细胞中的主要丝氨酸转运蛋白

Kelly O Conger, Christopher Chidley, Mete Emir Ozgurses, Huiping Zhao, Yumi Kim, Svetlana E Semina, Philippa Burns, Vipin Rawat, Ryan Sheldon, Issam Ben-Sahra, Jonna Frasor, Peter K Sorger, Gina M DeNicola, Jonathan L Coloff

Lineage-specific silencing of PSAT1 induces serine auxotrophy and sensitivity to dietary serine starvation in luminal breast tumors

PSAT1 的谱系特异性沉默会导致管腔型乳腺肿瘤出现丝氨酸营养缺陷和对膳食丝氨酸饥饿的敏感性。

Bo-Hyun Choi ,Vipin Rawat ,Jenny Högström ,Philippa A Burns ,Kelly O Conger ,Mete Emir Ozgurses ,Jaymin M Patel ,Tejas S Mehta ,Angelica Warren ,Laura M Selfors ,Taru Muranen ,Jonathan L Coloff

SOX2 mediates metabolic reprogramming of prostate cancer cells

SOX2 介导前列腺癌细胞的代谢重编程

Larischa de Wet, Anthony Williams, Marc Gillard, Steven Kregel, Sophia Lamperis, Lisa C Gutgesell, Jordan E Vellky, Ryan Brown, Kelly Conger, Gladell P Paner, Heng Wang, Elizabeth A Platz, Angelo M De Marzo, Ping Mu, Jonathan L Coloff, Russell Z Szmulewitz, Donald J Vander Griend

Differential substrate use in EGF- and oncogenic KRAS-stimulated human mammary epithelial cells

EGF 和致癌 KRAS 刺激的人类乳腺上皮细胞中的差异底物使用

Mark A Keibler, Wentao Dong, Keegan D Korthauer, Aaron M Hosios, Sun Jin Moon, Lucas B Sullivan, Nian Liu, Keene L Abbott, Orlando D Arevalo, Kailing Ho, Jennifer Lee, Aasavari S Phanse, Joanne K Kelleher, Othon Iliopoulos, Jonathan L Coloff, Matthew G Vander Heiden, Gregory Stephanopoulos

PHGDH supports liver ceramide synthesis and sustains lipid homeostasis

PHGDH 支持肝脏神经酰胺合成并维持脂质稳态

Yun Pyo Kang, Aimee Falzone, Min Liu, Paloma González-Sánchez, Bo-Hyun Choi, Jonathan L Coloff, James J Saller, Florian A Karreth, Gina M DeNicola

Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion

去泛素化酶在谷胱甘肽耗竭后维持蛋白质稳态和癌细胞存活

Isaac S Harris, Jennifer E Endress, Jonathan L Coloff, Laura M Selfors, Samuel K McBrayer, Jennifer M Rosenbluth, Nobuaki Takahashi, Sabin Dhakal, Vidyasagar Koduri, Matthew G Oser, Nathan J Schauer, Laura M Doherty, Andrew L Hong, Yun Pyo Kang, Scott T Younger, John G Doench, William C Hahn, Sara J

Starved epithelial cells uptake extracellular matrix for survival

饥饿的上皮细胞吸收细胞外基质以维持生存

Taru Muranen, Marcin P Iwanicki, Natasha L Curry, Julie Hwang, Cory D DuBois, Jonathan L Coloff, Daniel S Hitchcock, Clary B Clish, Joan S Brugge, Nada Y Kalaany

Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells

Akt调控糖酵解介导上皮细胞的生物能量稳定性

Yin P Hung # ,Carolyn Teragawa # ,Nont Kosaisawe ,Taryn E Gillies ,Michael Pargett ,Marta Minguet ,Kevin Distor ,Briana L Rocha-Gregg ,Jonathan L Coloff ,Mark A Keibler ,Gregory Stephanopoulos ,Gary Yellen ,Joan S Brugge ,John G Albeck

Differential Glutamate Metabolism in Proliferating and Quiescent Mammary Epithelial Cells

增殖和静止乳腺上皮细胞中的差异谷氨酸代谢

Jonathan L Coloff, J Patrick Murphy, Craig R Braun, Isaac S Harris, Laura M Shelton, Kenjiro Kami, Steven P Gygi, Laura M Selfors, Joan S Brugge