日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Intracranial non-germinomatous germ cell tumors in children and adolescents: how can the experience from an uppermiddle-income country contribute to the worldwide effort to improve outcomes?

儿童和青少年颅内非生殖细胞瘤生殖细胞肿瘤:中上收入国家的经验如何为全球改善治疗结果的努力做出贡献?

Andrea M Cappellano, Natalia Dassi, Bruna M Mançano, Sidnei Epelman, Daniela B Almeida, Sergio Cavalheiro, Patricia A Dastoli, Maria T S Alves, Jardel M Nicacio, Marcos D S Costa, Frederico A Silva, Simone S Aguiar, Maria L Figueiredo, Michael Chen, Nasjla S Silva, Jonathan L Finlay

Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis

种系 TP53 突变在肿瘤诊断前数年就会发生拷贝数增加

Nicholas Light, Mehdi Layeghifard #, Ayush Attery #, Vallijah Subasri, Matthew Zatzman, Nathaniel D Anderson, Rupal Hatkar, Sasha Blay, David Chen, Ana Novokmet, Fabio Fuligni, James Tran, Richard de Borja, Himanshi Agarwal, Larissa Waldman, Lisa M Abegglen, Daniel Albertson, Jonathan L Finlay, Jord

LLL12B, a small molecule STAT3 inhibitor, induces growth arrest, apoptosis, and enhances cisplatin-mediated cytotoxicity in medulloblastoma cells

LLL12B 是一种小分子 STAT3 抑制剂,可诱导髓母细胞瘤细胞生长停滞、细胞凋亡,并增强顺铂介导的细胞毒性

Xiang Chen #, Li Pan #, Jia Wei, Ruijie Zhang, Xiaozhi Yang, Jinhua Song, Ren-Yuan Bai, Shengling Fu, Christopher R Pierson, Jonathan L Finlay, Chenglong Li, Jiayuh Lin

ΔNp73/ETS2 complex drives glioblastoma pathogenesis- targeting downstream mediators by rebastinib prolongs survival in preclinical models of glioblastoma

ΔNp73/ETS2 复合物驱动胶质母细胞瘤发病机制 - 通过瑞巴替尼靶向下游介质延长胶质母细胞瘤临床前模型的生存期

Maren Cam, Manish Charan, Alessandra M Welker, Piyush Dravid, Adam W Studebaker, Jeffrey R Leonard, Christopher R Pierson, Ichiro Nakano, Christine E Beattie, Eugene I Hwang, Madhuri Kambhampati, Javad Nazarian, Jonathan L Finlay, Hakan Cam

Blocking interleukin-6 signaling inhibits cell viability/proliferation, glycolysis, and colony forming activity of human medulloblastoma cells

阻断白细胞介素 6 信号传导可抑制人类髓母细胞瘤细胞的细胞活力/增殖、糖酵解和集落形成活性

Xiang Chen, Jia Wei, Chenglong Li, Christopher R Pierson, Jonathan L Finlay, Jiayuh Lin

Phase I trial of dasatinib, lenalidomide, and temozolomide in children with relapsed or refractory central nervous system tumors

达沙替尼、来那度胺和替莫唑胺治疗复发或难治性中枢神经系统肿瘤患儿的 I 期临床试验

Nathan J Robison, Kee Kiat Yeo, Adrian P Berliner, Jemily Malvar, Michael A Sheard, Ashley S Margol, Robert C Seeger, Teresa Rushing, Jonathan L Finlay, Richard Sposto, Girish Dhall

Immune profiling of NF1-associated tumors reveals histologic subtype distinctions and heterogeneity: implications for immunotherapy

NF1 相关肿瘤的免疫分析揭示了组织学亚型的区别和异质性:对免疫治疗的意义

Kellie B Haworth, Michael A Arnold, Christopher R Pierson, Kwangmin Choi, Nicholas D Yeager, Nancy Ratner, Ryan D Roberts, Jonathan L Finlay, Timothy P Cripe

Disseminated Medulloblastoma in a Child with Germline BRCA2 6174delT Mutation and without Fanconi Anemia

患有生殖系 BRCA2 6174delT 突变且无范康尼贫血的儿童发生播散性髓母细胞瘤

Jingying Xu, Ashley Sloane Margol, Anju Shukla, Xiuhai Ren, Jonathan L Finlay, Mark D Krieger, Floyd H Gilles, Fergus J Couch, Meraj Aziz, Eric T Fung, Shahab Asgharzadeh, Michael T Barrett, Anat Erdreich-Epstein