日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

MCU gain- and loss-of-function models define the duality of mitochondrial calcium uptake in heart failure

MCU 功能获得和丧失模型定义了心力衰竭中线粒体钙摄取的二元性

Joanne F Garbincius, Timothy S Luongo, Jonathan P Lambert, Adam S Mangold, Emma K Murray, Alycia N Hildebrand, Pooja Jadiya, John W Elrod

Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure

心脏外 BCAA 分解代谢可降低血压并预防心力衰竭

Danielle Murashige, Jae Woo Jung, Michael D Neinast, Michael G Levin, Qingwei Chu, Jonathan P Lambert, Joanne F Garbincius, Boa Kim, Atsushi Hoshino, Ingrid Marti-Pamies, Kendra S McDaid, Swapnil V Shewale, Emily Flam, Steven Yang, Emilia Roberts, Li Li, Michael P Morley, Kenneth C Bedi Jr, Matthew

Altered composition of the mitochondrial Ca2+uniporter in the failing human heart

人类心脏衰竭时线粒体 Ca2+ 单向转运体的组成发生改变

Melanie Paillard, Kai-Ting Huang, David Weaver, Jonathan P Lambert, John W Elrod, György Hajnóczky

Abcg2-expressing side population cells contribute to cardiomyocyte renewal through fusion

表达 Abcg2 的侧群细胞通过融合促进心肌细胞更新

Amritha Yellamilli, Yi Ren, Ron T McElmurry, Jonathan P Lambert, Polina Gross, Sadia Mohsin, Steven R Houser, John W Elrod, Jakub Tolar, Daniel J Garry, Jop H van Berlo

Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimer's disease

线粒体钙外流受损导致阿尔茨海默病模型中的病情进展

Pooja Jadiya, Devin W Kolmetzky, Dhanendra Tomar, Antonio Di Meco, Alyssa A Lombardi, Jonathan P Lambert, Timothy S Luongo, Marthe H Ludtmann, Domenico Praticò, John W Elrod

Spatial Separation of Mitochondrial Calcium Uptake and Extrusion for Energy-Efficient Mitochondrial Calcium Signaling in the Heart

线粒体钙离子吸收和排出的空间分离,实现心脏中能量高效的线粒体钙信号传导

Sergio De La Fuente, Jonathan P Lambert, Zuzana Nichtova, Celia Fernandez Sanz, John W Elrod, Shey-Shing Sheu, György Csordás

The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability

线粒体 Na+/Ca2+ 交换器对于 Ca2+ 稳态和生存至关重要

Timothy S Luongo, Jonathan P Lambert, Polina Gross, Mary Nwokedi, Alyssa A Lombardi, Santhanam Shanmughapriya, April C Carpenter, Devin Kolmetzky, Erhe Gao, Jop H van Berlo, Emily J Tsai, Jeffery D Molkentin, Xiongwen Chen, Muniswamy Madesh, Steven R Houser, John W Elrod

Exercise training provides cardioprotection by activating and coupling endothelial nitric oxide synthase via a β3-adrenergic receptor-AMP-activated protein kinase signaling pathway

运动训练通过 β3-肾上腺素受体-AMP 活化蛋白激酶信号通路激活和偶联内皮型一氧化氮合酶,发挥心脏保护作用

Larry A Barr, Jonathan P Lambert, Yuuki Shimizu, Lili A Barouch, Nawazish Naqvi, John W Calvert

Sodium Sulfide Attenuates Ischemic-Induced Heart Failure by Enhancing Proteasomal Function in an Nrf2-Dependent Manner

硫化钠以 Nrf2 依赖的方式增强蛋白酶体功能,减轻缺血性心力衰竭

Yuuki Shimizu, Chad K Nicholson, Jonathan P Lambert, Larry A Barr, Nicholas Kuek, David Herszenhaut, Lin Tan, Toyoaki Murohara, Jason M Hansen, Ahsan Husain, Nawazish Naqvi, John W Calvert

DJ-1 protects the heart against ischemia-reperfusion injury by regulating mitochondrial fission

DJ-1 通过调节线粒体裂变保护心脏免受缺血再灌注损伤

Yuuki Shimizu, Jonathan P Lambert, Chad K Nicholson, Joshua J Kim, David W Wolfson, Hee Cheol Cho, Ahsan Husain, Nawazish Naqvi, Li-Shen Chin, Lian Li, John W Calvert