日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Scaffolds with optimized quaternary symmetry for de novo cryoEM structure determination of small RNAs

具有优化四级对称性的支架,用于从头冷冻电镜测定小RNA的结构

Jones, Christopher P; Ferré-D'Amaré, Adrian R

Machine Learning-Augmented Molecular Dynamics Simulations (MD) Reveal Insights Into the Disconnect Between Affinity and Activation of ZTP Riboswitch Ligands

机器学习增强的分子动力学模拟(MD)揭示了ZTP核糖开关配体亲和力和激活之间脱节的机制

Fullenkamp, Christopher R; Mehdi, Shams; Jones, Christopher P; Tenney, Logan; Pichling, Patricio; Prestwood, Peri R; Ferré-D'Amaré, Adrian R; Tiwary, Pratyush; Schneekloth, John S

Structural switching dynamically controls the doubly pseudoknotted Rous sarcoma virus-programmed ribosomal frameshifting element

结构转换动态控制着双假结劳氏肉瘤病毒编程的核糖体移码元件

Jones, Christopher P; Ferré-D'Amaré, Adrian R

Crystallographic and cryoEM analyses reveal SARS-CoV-2 SL5 is a mobile T-shaped four-way junction with deep pockets

晶体学和冷冻电镜分析表明,SARS-CoV-2 SL5 是一种具有深口袋的可移动 T 形四向连接结构。

Jones, Christopher P; Ferré-D'Amaré, Adrian R

Functional Relevance of CASP16 Nucleic Acid Predictions as Evaluated by Structure Providers

结构提供者对CASP16核酸预测的功能相关性的评估

Kretsch, Rachael C; Albrecht, Reinhard; Andersen, Ebbe S; Chen, Hsuan-Ai; Chiu, Wah; Das, Rhiju; Gezelle, Jeanine G; Hartmann, Marcus D; Höbartner, Claudia; Hu, Yimin; Jadhav, Shekhar; Johnson, Philip E; Jones, Christopher P; Koirala, Deepak; Kristoffersen, Emil L; Largy, Eric; Lewicka, Anna; Mackereth, Cameron D; Marcia, Marco; Nigro, Michela; Ojha, Manju; Piccirilli, Joseph A; Rice, Phoebe A; Shin, Heewhan; Steckelberg, Anna-Lena; Su, Zhaoming; Srivastava, Yoshita; Wang, Liu; Wu, Yuan; Xie, Jiahao; Zwergius, Nikolaj H; Moult, John; Kryshtafovych, Andriy

Functional relevance of CASP16 nucleic acid predictions as evaluated by structure providers

结构提供者对CASP16核酸预测的功能相关性进行了评估

Kretsch, Rachael C; Albrecht, Reinhard; Andersen, Ebbe S; Chen, Hsuan-Ai; Chiu, Wah; Das, Rhiju; Gezelle, Jeanine G; Hartmann, Marcus D; Höbartner, Claudia; Hu, Yimin; Jadhav, Shekhar; Johnson, Philip E; Jones, Christopher P; Koirala, Deepak; Kristoffersen, Emil L; Largy, Eric; Lewicka, Anna; Mackereth, Cameron D; Marcia, Marco; Nigro, Michela; Ojha, Manju; Piccirilli, Joseph A; Rice, Phoebe A; Shin, Heewhan; Steckelberg, Anna-Lena; Su, Zhaoming; Srivastava, Yoshita; Wang, Liu; Wu, Yuan; Xie, Jiahao; Zwergius, Nikolaj H; Moult, John; Kryshtafovych, Andriy

Discovery of Small Molecules Targeting the Frameshifting Element RNA in SARS-CoV-2 Viral Genome

发现靶向SARS-CoV-2病毒基因组移码元件RNA的小分子

Yang, Mo; Olatunji, Feyisola P; Rhodes, Curran; Balaratnam, Sumirtha; Dunne-Dombrink, Kara; Seshadri, Srinath; Liang, Xiao; Jones, Christopher P; Le Grice, Stuart F J; Ferré-D'Amaré, Adrian R; Schneekloth, John S Jr

Real-time monitoring of single ZTP riboswitches reveals a complex and kinetically controlled decision landscape

对单个 ZTP 核糖开关的实时监测揭示了一个复杂且受动力学控制的决策过程。

Hua, Boyang; Jones, Christopher P; Mitra, Jaba; Murray, Peter J; Rosenthal, Rebecca; Ferré-D'Amaré, Adrian R; Ha, Taekjip

Parallel Discovery Strategies Provide a Basis for Riboswitch Ligand Design

并行发现策略为核糖开关配体设计提供了基础

Tran, Brandon; Pichling, Patricio; Tenney, Logan; Connelly, Colleen M; Moon, Michelle H; Ferré-D'Amaré, Adrian R; Schneekloth, John S Jr; Jones, Christopher P

Structural and compositional characteristics of Fukushima release particulate material from Units 1 and 3 elucidates release mechanisms, accident chronology and future decommissioning strategy

福岛核电站1号和3号机组释放颗粒物的结构和成分特征阐明了释放机制、事故时间顺序和未来的退役策略。

Martin, Peter G; Jones, Christopher P; Bartlett, Stuart; Ignatyev, Konstantin; Megson-Smith, Dave; Satou, Yukihiko; Cipiccia, Silvia; Batey, Darren J; Rau, Christoph; Sueki, Keisuke; Ishii, Tatsuya; Igarashi, Junya; Ninomiya, Kazuhiko; Shinohara, Atsushi; Rust, Alison; Scott, Thomas B