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DNA methylation differences between cord and adult white blood cells reflect postnatal immune cell maturation

脐带血白细胞和成人白细胞之间的DNA甲基化差异反映了出生后免疫细胞的成熟情况。

doi:10.1038/s42003-025-07661-4

Jones, Meaghan J; Konwar, Chaini; Asiimwe, Rebecca; Dinh, Louie; Razzaghian, Hamid Reza; de Goede, Olivia; MacIsaac, Julia L; Morin, Alexander M; Kolsun, Kurt P; Gervin, Kristina; Lyle, Robert; Ng, Raymond T; Koestler, Devin C; Felix, Janine F; Lavoie, Pascal M; Robinson, Wendy P; Mostafavi, Sara; Kobor, Michael S

In-utero exposure to maternal diabetes and DNA methylation alterations in the Next Generation birth cohort

下一代出生队列研究中，子宫内暴露于母体糖尿病和DNA甲基化改变的情况

期刊:Clinical Epigenetics

影响因子:4.4

doi:10.1186/s13148-025-01972-3

Salama, Ola E; Rawal, Yash; Irabor, Priscilla; Kassim, Haziqa; Pylypjuk, Christy; Sellers, Elizabeth A C; Wicklow, Brandy A; Jones, Meaghan J

Association between maternal perinatal stress and depression and infant DNA methylation in the first year of life

母亲围产期压力和抑郁与婴儿出生第一年DNA甲基化之间的关联

期刊:Translational Psychiatry

影响因子:6.2

doi:10.1038/s41398-024-03148-8

Abrishamcar, Sarina; Zhuang, Beryl C; Thomas, Mara; Gladish, Nicole; MacIsaac, Julia L; Jones, Meaghan J; Simons, Elinor; Moraes, Theo J; Mandhane, Piush J; Brook, Jeffrey R; Subbarao, Padmaja; Turvey, Stuart E; Chen, Edith; Miller, Gregory E; Kobor, Michael S; Hüls, Anke

DNA methylation signatures of youth-onset type 2 diabetes and exposure to maternal diabetes

青少年发病型2型糖尿病的DNA甲基化特征及母体糖尿病暴露

期刊:Clinical Epigenetics

影响因子:4.4

doi:10.1186/s13148-024-01675-1

Salama, Ola E; Hizon, Nikho; Del Vecchio, Melissa; Kolsun, Kurt; Fonseca, Mario A; Lin, David T S; Urtatiz, Oscar; MacIsaac, Julia L; Kobor, Michael S; Sellers, Elizabeth A C; Dolinsky, Vernon W; Dart, Allison B; Jones, Meaghan J; Wicklow, Brandy A

Early-life exposure to cigarette smoke primes lung function and DNA methylation changes at Cyp1a1 upon exposure later in life

早期接触香烟烟雾会影响肺功能，并在日后再次接触时导致 Cyp1a1 基因的 DNA 甲基化改变。

期刊:American Journal of Physiology-Lung Cellular and Molecular Physiology

影响因子:3.5

doi:10.1152/ajplung.00192.2023

Onuzulu, Chinonye Doris; Lee, Samantha; Basu, Sujata; Comte, Jeannette; Hai, Yan; Hizon, Nikho; Chadha, Shivam; Fauni, Maria Shenna; Kahnamoui, Shana; Xiang, Bo; Halayko, Andrew J; Dolinsky, Vernon W; Pascoe, Christopher D; Jones, Meaghan J

表观遗传

发表日期：2023

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DNA methylation is not associated with sensitization to or dietary introduction of highly allergenic foods in a subset of the CHILD cohort at age 1 year

在 CHILD 队列研究的一个子集中，1 岁时 DNA 甲基化与对高致敏性食物的致敏或饮食中引入高致敏性食物无关。

期刊:Journal of Allergy and Clinical Immunology Global

影响因子:

doi:10.1016/j.jacig.2023.100130

Kolsun, Kurt P; Lee, Samantha; MacIsaac, Julia L; Subbarao, Padmaja; Moraes, Theo J; Mandhane, Piushkumar J; Turvey, Stuart E; Kobor, Michael S; Jones, Meaghan J; Simons, Elinor

表观遗传

发表日期：2023

文献求助收藏

In-utero exposure to indoor air pollution or tobacco smoke and cognitive development in a South African birth cohort study

南非一项出生队列研究探讨了子宫内暴露于室内空气污染或烟草烟雾与认知发育之间的关系。

期刊:Science of the Total Environment

影响因子:8

doi:10.1016/j.scitotenv.2022.155394

Christensen, Grace M; Rowcliffe, Claire; Chen, Junyu; Vanker, Aneesa; Koen, Nastassja; Jones, Meaghan J; Gladish, Nicole; Hoffman, Nadia; Donald, Kirsten A; Wedderburn, Catherine J; Kobor, Michael S; Zar, Heather J; Stein, Dan J; Hüls, Anke

Newborn differential DNA methylation and subcortical brain volumes as early signs of severe neurodevelopmental delay in a South African Birth Cohort Study

南非出生队列研究发现，新生儿DNA甲基化差异和皮层下脑容量是严重神经发育迟缓的早期征兆。

期刊:World Journal of Biological Psychiatry

影响因子:3.8

doi:10.1080/15622975.2021.2016955

Hüls, Anke; Wedderburn, Catherine J; Groenewold, Nynke A; Gladish, Nicole; Jones, Meaghan J; Koen, Nastassja; MacIsaac, Julia L; Lin, David T S; Ramadori, Katia E; Epstein, Michael P; Donald, Kirsten A; Kobor, Michael S; Zar, Heather J; Stein, Dan J

Immune cell type and DNA methylation vary with reproductive status in women: possible pathways for costs of reproduction

女性的免疫细胞类型和DNA甲基化随生育状态而变化：这可能是生育成本的途径

期刊:Evolution Medicine and Public Health

影响因子:2.1

doi:10.1093/emph/eoac003

Ryan, Calen P; Jones, Meaghan J; Edgar, Rachel D; Lee, Nanette R; Kobor, Michael S; McDade, Thomas W; Kuzawa, Christopher W

Designing Epigenetic Clocks for Wildlife Research

为野生动物研究设计表观遗传时钟

DNA methylation differences between cord and adult white blood cells reflect postnatal immune cell maturation

脐带血白细胞和成人白细胞之间的DNA甲基化差异反映了出生后免疫细胞的成熟情况。

In-utero exposure to maternal diabetes and DNA methylation alterations in the Next Generation birth cohort

下一代出生队列研究中，子宫内暴露于母体糖尿病和DNA甲基化改变的情况

Association between maternal perinatal stress and depression and infant DNA methylation in the first year of life

母亲围产期压力和抑郁与婴儿出生第一年DNA甲基化之间的关联

DNA methylation signatures of youth-onset type 2 diabetes and exposure to maternal diabetes

青少年发病型2型糖尿病的DNA甲基化特征及母体糖尿病暴露

Early-life exposure to cigarette smoke primes lung function and DNA methylation changes at Cyp1a1 upon exposure later in life

早期接触香烟烟雾会影响肺功能，并在日后再次接触时导致 Cyp1a1 基因的 DNA 甲基化改变。

DNA methylation is not associated with sensitization to or dietary introduction of highly allergenic foods in a subset of the CHILD cohort at age 1 year

在 CHILD 队列研究的一个子集中，1 岁时 DNA 甲基化与对高致敏性食物的致敏或饮食中引入高致敏性食物无关。

In-utero exposure to indoor air pollution or tobacco smoke and cognitive development in a South African birth cohort study

南非一项出生队列研究探讨了子宫内暴露于室内空气污染或烟草烟雾与认知发育之间的关系。

Newborn differential DNA methylation and subcortical brain volumes as early signs of severe neurodevelopmental delay in a South African Birth Cohort Study

南非出生队列研究发现，新生儿DNA甲基化差异和皮层下脑容量是严重神经发育迟缓的早期征兆。

Immune cell type and DNA methylation vary with reproductive status in women: possible pathways for costs of reproduction

女性的免疫细胞类型和DNA甲基化随生育状态而变化：这可能是生育成本的途径