日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

FGF1 ameliorates hepatic steatosis through acute activation of the unfolded protein response and VLDL production

FGF1通过急性激活未折叠蛋白反应和VLDL生成来改善肝脂肪变性。

van Zutphen, Tim; Struik, Dicky; Liu, Weilin; Liu, Sihao; Sermikli, Benan Pelin; Wolters, Justina C; Verkade, Henkjan J; Atkins, Annette R; Downes, Michael; Evans, Ronald M; Jonker, Johan W

Assessing Nutraceuticals for Hepatic Steatosis: A Standardized In Vitro Approach

评估营养保健品对肝脂肪变性的影响:一种标准化的体外方法

Palasantzas, Victoria E J M; Struik, Dicky; Bos, Trijnie; Withoff, Sebo; Fu, Jingyuan; Jonker, Johan W; Hoogerland, Joanne A

Loss of Early Growth Response Protein 1 in the Liver Leads to Hepatic Lipid Accumulation Driven by an Imbalance Between Fatty Acid β-Oxidation and Oxidative Phosphorylation.

肝脏中早期生长反应蛋白 1 的缺失导致肝脏脂质积累,这是由于脂肪酸 β-氧化和氧化磷酸化之间的不平衡所致。

Verzijl Cristy R C, Struik Dicky, Gerding Albert, Eilers Roos E, Thomas Rachel E, Koster Mirjam, Langelaar-Makkinje Miriam, Smit Marieke, Huijkman Nicolette, Havinga Rick, Kloosterhuis Niels, Bloks Vincent W, Wolters Justina C, de Boer Jan Freark, van de Sluis Bart, Bakker Barbara M, Jonker Johan W

Beta-Klotho Protein Expression in Healthy Human Tissues and Liver Biopsies From Patients With MASLD or MASH.

健康人体组织和 MASLD 或 MASH 患者肝脏活检中 β-Klotho 蛋白的表达

Aaldijk Alexandra S, Struik Dicky, Driessen Stan, Verzijl Cristy R C, Verheij Joanne, Nieuwdorp Max, Eilers Roos, Wolters Justina C, Holleboom Adriaan G, Jonker Johan W

Biological and pharmacological functions of the FGF19- and FGF21-coreceptor beta klotho

FGF19 和 FGF21 共受体 β-klotho 的生物学和药理学功能

Aaldijk, Alexandra S; Verzijl, Cristy R C; Jonker, Johan W; Struik, Dicky

Failure to repair endogenous DNA damage in β-cells causes adult-onset diabetes in mice

小鼠β细胞内源性DNA损伤修复失败会导致成年期糖尿病。

Yousefzadeh, Matthew J; Huerta Guevara, Ana P; Postmus, Andrea C; Flores, Rafael R; Sano, Tokio; Jurdzinski, Angelika; Angelini, Luise; McGowan, Sara J; O'Kelly, Ryan D; Wade, Erin A; Gonzalez-Espada, Lisa V; Henessy-Wack, Danielle; Howard, Shannon; Rozgaja, Tania A; Trussoni, Christy E; LaRusso, Nicholas F; Eggen, Bart J L; Jonker, Johan W; Robbins, Paul D; Niedernhofer, Laura J; Kruit, Janine K

Autocrine FGF1 signaling promotes glucose uptake in adipocytes

自分泌FGF1信号促进脂肪细胞对葡萄糖的摄取

Nies, Vera J M; Struik, Dicky; Liu, Sihao; Liu, Weilin; Kruit, Janine K; Downes, Michael; van Zutphen, Tim; Verkade, Henkjan J; Evans, Ronald M; Jonker, Johan W

Increased insulin sensitivity and diminished pancreatic beta-cell function in DNA repair deficient Ercc1(d/-) mice

DNA修复缺陷型Ercc1(d/-)小鼠表现出胰岛素敏感性增加和胰腺β细胞功能减弱。

Huerta Guevara, Ana P; McGowan, Sara J; Kazantzis, Melissa; Stallons, Tania Rozgaja; Sano, Tokio; Mulder, Niels L; Jurdzinski, Angelika; van Dijk, Theo H; Eggen, Bart J L; Jonker, Johan W; Niedernhofer, Laura J; Kruit, Janine K

Abnormal Liver Function Tests in Patients With COVID-19: Relevance and Potential Pathogenesis

COVID-19 患者肝功能异常:相关性及潜在发病机制

Bertolini, Anna; van de Peppel, Ivo P; Bodewes, Frank A J A; Moshage, Han; Fantin, Alberto; Farinati, Fabio; Fiorotto, Romina; Jonker, Johan W; Strazzabosco, Mario; Verkade, Henkjan J; Peserico, Giulia

The Role of Lipophagy in the Development and Treatment of Non-Alcoholic Fatty Liver Disease

脂质自噬在非酒精性脂肪肝疾病的发生发展和治疗中的作用

Grefhorst, Aldo; van de Peppel, Ivo P; Larsen, Lars E; Jonker, Johan W; Holleboom, Adriaan G