Jooman相关文献与解析，生知库 | 链接生命科学的每一步

Hu Ruoci, Park Jooman, Qian Yanyu, Xiong Shaolei, Elsabbagh Ahmad Hamza, Chhikara Aditya, Fan Huailing, Shi Zuoxiao, Liu Lifeng, Li Yanhui, Song Zhenyuan, Mahmoud Abeer M, Chen Jiwang, Baur Joseph A, He Yanlin, Layden Brian T, Zhou Zhenqi, Xu Pingwen, Ong Sang-Ging, Wang Zilai, Jiang Yuwei

IL-3

IL-33

信号转导

Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction

靶向脂肪组织功能可预防射血分数保留型心力衰竭

期刊:Advanced Science

影响因子:

doi:10.1002/advs.202506106

Jousma, Jordan; Han, Zhenbo; Park, Jooman; Yan, Gege; Zhang, Sen; Kwon, Youjeong; Nukala, Sarath Babu; Kandola, Jindpreet; Pinho, Sandra; Liew, Chong Wee; Jiang, Yuwei; Ong, Sang-Ging

Skeletal muscle endothelial dysfunction through the activin A-PGC1α axis drives progression of cancer cachexia

骨骼肌内皮功能障碍通过激活素A-PGC1α轴驱动癌症恶病质的进展

期刊:Nature Cancer

影响因子:23.5

doi:10.1038/s43018-025-00975-6

Young-Mee Kim ，Mark A Sanborn ，Shaluah Vijeth ，Priyanka Gajwani ，Xinge Wang ，Dahee Jung ，Tibor Valyi-Nagy ，Sreeparna Chakraborty ，Georgina Mancinelli ，Peter T Toth ，Evan H Phillips ，Paul Grippo ，Ameen A Salahudeen ，Jooman Park ，Su Yeon Yeon ，Vijayalakshmi Ananthanarayanan ，Yuwei Jiang ，Steve Seung-Young Lee ，Klara Valyi-Nagy ，Jalees Rehman

P21-activated kinase-1 signaling is required to preserve adipose tissue homeostasis and cardiac function.

P21激活激酶-1信号传导对于维持脂肪组织稳态和心脏功能是必需的

期刊:Molecular and Cellular Biochemistry

影响因子:3.7

doi:10.1007/s11010-024-04968-4

Munoz Marcos, Solis Christopher, McCann Maximilian, Park Jooman, Rafael-Clyke Koreena, Chowdhury Shamim A K, Jiang Yuwei, Rosas Paola C

心血管

发表日期：2025

文献求助收藏

Estrogen counteracts age-related decline in beige adipogenesis through the NAMPT-regulated ER stress response

雌激素通过NAMPT调节的内质网应激反应来对抗与年龄相关的米色脂肪细胞生成减少。

期刊:Nature Aging

影响因子:17

doi:10.1038/s43587-024-00633-z.

Jooman Park #,Ruoci Hu #,Yanyu Qian,Shaolei Xiong,Asma Sana El-Sabbagh,Meram Ibrahim,Jaden Wang,Ziqiao Xu,Zhengjia Chen,Qing Song,Zhenyuan Song,Gege Yan,Abeer M Mahmoud,Yanlin He,Brian T Layden,Jiwang Chen,Sang-Ging Ong,Pingwen Xu,Yuwei Jiang

Gut-derived ammonia contributes to alcohol-related fatty liver development via facilitating ethanol metabolism and provoking ATF4-dependent de novo lipogenesis activation

肠道来源的氨通过促进乙醇代谢和激活ATF4依赖的从头脂肪生成，促进酒精相关性脂肪肝的发生发展。

期刊:Metabolism-Clinical and Experimental

影响因子:11.9

doi:10.1016/j.metabol.2023.155740

Song, Qing; Hwang, Chueh-Lung; Li, Yanhui; Wang, Jun; Park, Jooman; Lee, Samuel M; Sun, Zhaoli; Sun, Jun; Xia, Yinglin; Nieto, Natalia; Cordoba-Chacon, Jose; Jiang, Yuwei; Dou, Xiaobing; Song, Zhenyuan

Macrophage-derived chemokine CCL22 establishes local LN-mediated adaptive thermogenesis and energy expenditure

巨噬细胞衍生的趋化因子CCL22可建立局部淋巴结介导的适应性产热和能量消耗。

期刊:Science Advances

影响因子:11.7

doi:10.1126/sciadv.adn5229

Yexian Yuan ，Ruoci Hu ，Jooman Park ，Shaolei Xiong ，Zilai Wang ，Yanyu Qian ，Zuoxiao Shi ，Ruifan Wu ，Zhenbo Han ，Sang-Ging Ong ，Shuhao Lin ，Krista A Varady ，Pingwen Xu ，Daniel C Berry ，Gang Shu ，Yuwei Jiang

The Notch-PDGFRβ axis suppresses brown adipocyte progenitor differentiation in early post-natal mice

Notch-PDGFRβ轴抑制出生早期小鼠棕色脂肪细胞祖细胞的分化

期刊:Developmental Cell

影响因子:10.7

doi:10.1016/j.devcel.2024.03.012

Zuoxiao Shi ，Shaolei Xiong ，Ruoci Hu ，Zilai Wang ，Jooman Park ，Yanyu Qian ，Jaden Wang ，Pratibha Bhalla ，Nipun Velupally ，Qing Song ，Zhenyuan Song ，Minsun Stacey Jeon ，Ke Kurt Zhang ，Linlin Xie ，Brian T Layden ，Sang-Ging Ong ，Yuwei Jiang

Genetically prolonged beige fat in male mice confers long-lasting metabolic health

遗传延长的雄性小鼠米色脂肪可带来持久的代谢健康

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-023-38471-z

Ruifan Wu #, Jooman Park #, Yanyu Qian, Zuoxiao Shi, Ruoci Hu, Yexian Yuan, Shaolei Xiong, Zilai Wang, Gege Yan, Sang-Ging Ong, Qing Song, Zhenyuan Song, Abeer M Mahmoud, Pingwen Xu, Congcong He, Robert W Arpke, Michael Kyba, Gang Shu, Qingyan Jiang, Yuwei Jiang3

代谢

发表日期：2023

文献求助收藏

mTORC1 inhibition uncouples lipolysis and thermogenesis in white adipose tissue to contribute to alcoholic liver disease

mTORC1 抑制可使白色脂肪组织中的脂肪分解与产热作用分离，从而导致酒精性肝病

期刊:Hepatology Communications

影响因子:5.6

doi:10.1097/HC9.0000000000000059

Qing Song, Yingli Chen, Qinchao Ding, Alexandra Griffiths, Lifeng Liu, Jooman Park, Chong Wee Liew, Natalia Nieto, Songtao Li, Xiaobing Dou, Yuwei Jiang, Zhenyuan Song

ERÎ± activates NAMPT/IL-33 signaling to enhance beige thermogenesis and metabolic fitness.

ERÎ±激活NAMPT/IL-33信号通路，增强米色细菌产热和代谢适应性。

Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction

靶向脂肪组织功能可预防射血分数保留型心力衰竭

Skeletal muscle endothelial dysfunction through the activin A-PGC1α axis drives progression of cancer cachexia

骨骼肌内皮功能障碍通过激活素A-PGC1α轴驱动癌症恶病质的进展

P21-activated kinase-1 signaling is required to preserve adipose tissue homeostasis and cardiac function.

P21激活激酶-1信号传导对于维持脂肪组织稳态和心脏功能是必需的

Estrogen counteracts age-related decline in beige adipogenesis through the NAMPT-regulated ER stress response

雌激素通过NAMPT调节的内质网应激反应来对抗与年龄相关的米色脂肪细胞生成减少。

Gut-derived ammonia contributes to alcohol-related fatty liver development via facilitating ethanol metabolism and provoking ATF4-dependent de novo lipogenesis activation

肠道来源的氨通过促进乙醇代谢和激活ATF4依赖的从头脂肪生成，促进酒精相关性脂肪肝的发生发展。

Macrophage-derived chemokine CCL22 establishes local LN-mediated adaptive thermogenesis and energy expenditure

巨噬细胞衍生的趋化因子CCL22可建立局部淋巴结介导的适应性产热和能量消耗。

The Notch-PDGFRβ axis suppresses brown adipocyte progenitor differentiation in early post-natal mice

Notch-PDGFRβ轴抑制出生早期小鼠棕色脂肪细胞祖细胞的分化

Genetically prolonged beige fat in male mice confers long-lasting metabolic health

遗传延长的雄性小鼠米色脂肪可带来持久的代谢健康

mTORC1 inhibition uncouples lipolysis and thermogenesis in white adipose tissue to contribute to alcoholic liver disease

mTORC1 抑制可使白色脂肪组织中的脂肪分解与产热作用分离，从而导致酒精性肝病