日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

3H-pyrazolo[4,3-f]quinoline hinge binder, a tunable scaffold for development of novel kinase inhibitors against FLT3-driven leukemia

3H-吡唑并[4,3-f]喹啉铰链结合剂，一种可用于开发新型抗FLT3驱动白血病激酶抑制剂的可调支架

期刊:European Journal of Medicinal Chemistry
影响因子:5.9
doi:10.1016/j.ejmech.2025.118309
Dayal, Neetu; Řezníčková, Eva; Hernandez, Delmis E; Peřina, Miroslav; Bělíček, Jakub; Vojáčková, Veronika; Krňávková, Petra; Bařina, Marek; Brauer, Nickolas R; Hunjan, Mandeep Kaur; Yadav, Pratik; Jorda, Radek; Sintim, Herman O
白血病
信号转导
FLT3
发表日期：2026
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Isoxazole-Based Compounds Targeting the Taxane-Binding Site of Tubulin.

靶向微管蛋白紫杉烷结合位点的异噁唑类化合物

期刊:Archiv der Pharmazie
影响因子:3.6
doi:10.1002/ardp.70031
Peřina Miroslav, Kiss Márton A, Bělíček Jakub, Vojáčková Veronika, Veselá Denisa, Minorics Renáta, Zupko István, Frank Éva, Jorda Radek
免疫/内分泌
发表日期：2025
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Cyclin dependent kinase 4/6 inhibitor palbociclib synergizes with BCL2 inhibitor venetoclax in experimental models of mantle cell lymphoma without RB1 deletion

在不伴有RB1缺失的套细胞淋巴瘤实验模型中，细胞周期蛋白依赖性激酶4/6抑制剂帕博西尼与BCL2抑制剂维奈托克具有协同作用

期刊:Experimental Hematology & Oncology
影响因子:13.5
doi:10.1186/s40164-024-00499-2
Malarikova, Diana; Jorda, Radek; Kupcova, Kristyna; Senavova, Jana; Dolnikova, Alexandra; Pokorna, Eva; Kazantsev, Dmitry; Nozickova, Kristina; Sovilj, Dana; Bellanger, Celine; Chiron, David; Andera, Ladislav; Krystof, Vladimir; Strnad, Miroslav; Helman, Karel; Klanova, Magdalena; Trneny, Marek; Havranek, Ondrej; Klener, Pavel
信号转导
细胞生物学
BCL2
淋巴瘤
发表日期：2024
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Anticancer effect of zanubrutinib in HER2-positive breast cancer cell lines

zanubrutinib 对 HER2 阳性乳腺癌细胞系的抗癌作用

期刊:Investigational New Drugs
影响因子:2.7
doi:10.1007/s10637-023-01346-7
Dostálová, Hana; Jorda, Radek; Řezníčková, Eva; Kryštof, Vladimír
肿瘤
HER2
肿瘤免疫
乳腺癌
细胞生物学
发表日期：2023
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Synthesis and Structural Optimization of 2,7,9-Trisubstituted purin-8-ones as FLT3-ITD Inhibitors

2,7,9-三取代嘌呤-8-酮作为FLT3-ITD抑制剂的合成与结构优化

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms232416169
Tomanová, Monika; Kozlanská, Karolína; Jorda, Radek; Jedinák, Lukáš; Havlíková, Tereza; Řezníčková, Eva; Peřina, Miroslav; Klener, Pavel; Dolníková, Alexandra; Cankař, Petr; Kryštof, Vladimír
FLT3
发表日期：2022
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