Integrative analyses of TEDDY Omics data reveal lipid metabolism abnormalities, increased intracellular ROS and heightened inflammation prior to autoimmunity for type 1 diabetes
TEDDY 组学数据的综合分析揭示了 1 型糖尿病在自身免疫之前存在脂质代谢异常、细胞内 ROS 增加和炎症加剧
期刊:Genome Biology
影响因子:10.1
doi:10.1186/s13059-021-02262-w
Leandro Balzano-Nogueira, Ricardo Ramirez, Tatyana Zamkovaya, Jordan Dailey, Alexandria N Ardissone, Srikar Chamala, Joan Serrano-Quílez, Teresa Rubio, Michael J Haller, Patrick Concannon, Mark A Atkinson, Desmond A Schatz, Eric W Triplett, Ana Conesa
代谢
免疫
糖尿病
其它细胞
Immunology/Inflammation
