日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structure, mechanism and clinical relevance of NRG1 fusions in cancer

NRG1融合的结构、机制及其在癌症中的临床意义

Thiollier-Schmitt, Clarisse; Barre, Manon; Issenmann, Marie; Cros-Perrial, Emeline; Duruisseaux, Michaël; Jordheim, Lars Petter

Third-Generation CD73 Inhibitors Based on a 4,6-Disubstituted-2-Thiopyridine Scaffold

基于4,6-二取代-2-噻吩吡啶骨架的第三代CD73抑制剂

Grosjean, Félix; Shaldaeva, Maria; Cros-Perrial, Emeline; Rodriguez, Céline; Ghoteimi, Rayane; Lebrun, Aurélien; Gao, Zhan-Guo; Uttaro, Jean-Pierre; Mathé, Christophe; Jacobson, Kenneth A; Petter Jordheim, Lars; Ménétrier-Caux, Christine; Chaloin, Laurent; Peyrottes, Suzanne

A systemically administered detoxified TLR4 agonist displays potent antitumor activity and an acceptable tolerance profile in preclinical models

系统性给药的去毒 TLR4 激动剂在临床前模型中表现出强大的抗肿瘤活性和可接受的耐受性

Kamel Chettab, Chantel Fitzsimmons, Alexey Novikov, Morgane Denis, Capucine Phelip, Doriane Mathé, Pierre Antoine Choffour, Sabine Beaumel, Eric Fourmaux, Patrick Norca, David Kryza, Anne Evesque, Lars Petter Jordheim, Emeline Perrial, Eva-Laure Matera, Martine Caroff, Jerome Kerzerho, Charles Dumon

A systemically administered detoxified TLR4 agonist displays potent antitumor activity and an acceptable tolerance profile in preclinical models

经全身给药的脱毒TLR4激动剂在临床前模型中显示出强大的抗肿瘤活性和可接受的耐受性。

Kamel Chettab,Chantel Fitzsimmons,Alexey Novikov,Morgane Denis,Capucine Phelip,Doriane Mathé,Pierre Antoine Choffour,Sabine Beaumel,Eric Fourmaux,Patrick Norca,David Kryza,Anne Evesque,Lars Petter Jordheim,Emeline Perrial,Eva-Laure Matera,Martine Caroff,Jerome Kerzerho,Charles Dumontet

How Staphylococcus aureus and Pseudomonas aeruginosa Hijack the Host Immune Response in the Context of Cystic Fibrosis

金黄色葡萄球菌和铜绿假单胞菌如何在囊性纤维化背景下劫持宿主免疫反应

Souche, Aubin; Vandenesch, François; Doléans-Jordheim, Anne; Moreau, Karen

A Proposed Methodology to Deal with the Impact of In Vitro Cellular Matrix on the Analytical Performances of a Targeted Metabolomic LC-HRMS Method

提出一种处理体外细胞基质对靶向代谢组学 LC-HRMS 方法分析性能影响的方法

Jérôme Guitton, Floriane Gavotto, Emeline Cros-Perrial, Lars Petter Jordheim, Christelle Machon

Advancing quantification methods for polyphenols in brown seaweeds-applying a selective qNMR method compared with the TPC assay

推进褐藻中多酚的定量方法——应用选择性 qNMR 方法与 TPC 测定进行比较

Marie Emilie Wekre, Sondre Hellesen Brunvoll, Monica Jordheim

Enhanced migration of breast and lung cancer cells deficient for cN-II and CD73 via COX-2/PGE2/AKT axis regulation

通过COX-2/PGE2/AKT轴调控增强cN-II和CD73缺陷的乳腺癌和肺癌细胞的迁移能力。

Cadassou, Octavia; Raza, Muhammad-Zawwad; Machon, Christelle; Gudefin, Laura; Armanet, Célia; Chettab, Kamel; Guitton, Jérôme; Tozzi, Maria Grazia; Dumontet, Charles; Cros-Perrial, Emeline; Jordheim, Lars Petter

Cytosolic 5'-Nucleotidase II Silencing in Lung Tumor Cells Regulates Metabolism through Activation of the p53/AMPK Signaling Pathway

肺癌细胞中胞浆 5'-核苷酸酶 II 沉默通过激活 p53/AMPK 信号通路调节代谢

Rossana Pesi, Simone Allegrini, Mercedes Garcia-Gil, Lucia Piazza, Roberta Moschini, Lars Petter Jordheim, Marcella Camici, Maria Grazia Tozzi

Characterization of T-DM1-resistant breast cancer cells

T-DM1 耐药乳腺癌细胞的表征

Juliette Sauveur, Louise Conilh, Sabine Beaumel, Kamel Chettab, Lars-Petter Jordheim, Eva-Laure Matera, Charles Dumontet