日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

In vivo deletion of a GWAS-identified Myb distal enhancer acts on Myb expression, globin switching, and clinical erythroid parameters in β-thalassemia

体内敲除 GWAS 鉴定的 Myb 远端增强子会影响 β-地中海贫血患者的 Myb 表达、珠蛋白转换和临床红系参数。

Deleuze, Virginie; Stephen, Tharshana; Salma, Mohammad; Orfeo, Cédric; Jorna, Ruud; Maas, Alex; Barroca, Vilma; Arcangeli, Marie-Laure; Lecellier, Charles-Henri; Andrieu-Soler, Charlotte; Grosveld, Frank; Soler, Eric

Transcription regulation by distal enhancers: who's in the loop?

远端增强子对转录的调控:谁在起作用?

Stadhouders, Ralph; van den Heuvel, Anita; Kolovos, Petros; Jorna, Ruud; Leslie, Kris; Grosveld, Frank; Soler, Eric

A novel complex, RUNX1-MYEF2, represses hematopoietic genes in erythroid cells

一种新型复合物RUNX1-MYEF2可抑制红系细胞中的造血基因。

van Riel, Boet; Pakozdi, Tibor; Brouwer, Rutger; Monteiro, Rui; Tuladhar, Kapil; Franke, Vedran; Bryne, Jan Christian; Jorna, Ruud; Rijkers, Erik-Jan; van Ijcken, Wilfred; Andrieu-Soler, Charlotte; Demmers, Jeroen; Patient, Roger; Soler, Eric; Lenhard, Boris; Grosveld, Frank

Human placenta is a potent hematopoietic niche containing hematopoietic stem and progenitor cells throughout development.

人类胎盘是一个强大的造血微环境,在整个发育过程中都含有造血干细胞和祖细胞

Robin Catherine, Bollerot Karine, Mendes Sandra, Haak Esther, Crisan Mihaela, Cerisoli Francesco, Lauw Ivoune, Kaimakis Polynikis, Jorna Ruud, Vermeulen Mark, Kayser Manfred, van der Linden Reinier, Imanirad Parisa, Verstegen Monique, Nawaz-Yousaf Humaira, Papazian Natalie, Steegers Eric, Cupedo Tom, Dzierzak Elaine