日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mutation of PXR phosphorylation motif at Ser347 disrupts lipid and bile acid homeostasis in diet-induced metabolic dysfunction-associated steatohepatitis in mice

小鼠饮食诱导的代谢功能障碍相关性脂肪性肝炎中,PXR磷酸化基序Ser347位点的突变会破坏脂质和胆汁酸稳态。

Basaly, Veronia; Henry, Zakiyah R; Taylor, Rulaiha E; Kong, Bo; Yang, Ill; Brinker, Anita; Yang, Zhenning; Zhou, Peihong; Joseph, Laurie B; Aleksunes, Lauren; Buckley, Brian; Negishi, Masahiko; Guo, Grace L

Deletion of hepatic FXR leads to more severe MASH development in female mice

肝脏FXR基因缺失会导致雌性小鼠发生更严重的MASH(黏膜相关血液系统疾病)

Henry, Zakiyah R; Armstrong, Laura; Maliha, Syeda; Jia, Xuelian; Gao, Sophie; Taylor, Rulaiha E; Basaly, Veronia; Otersen, Katherine; Yang, Zhenning; Rizzolo, Daniel; Stofan, Mary; Meadows, Vik; Bhattacharya, Anisha; Zhou, Peihong; Yang, Ill; Brinker, Anita; Zhou, Lanjing; Zhu, Hao; Joseph, Laurie B; Buckley, Brian; Anthony, Tracy; Aleksunes, Lauren; Kong, Bo; Guo, Grace L

Ursodeoxycholic acid acts as an ileal FXR agonist in male mice with hepatic deficiency of FXR

熊去氧胆酸在肝脏FXR缺乏的雄性小鼠中作为回肠FXR激动剂发挥作用

Henry, Zakiyah R; Maliha, Syeda; Basaly, Veronia; Yang, Zhenning; Taylor, Rulaiha E; Otersen, Katherine; Meadows, Vik; Rizzolo, Daniel; Stofan, Mary; Bhattacharya, Anisha; Zhou, Peihong; Brinker, Anita; Yang, Ill; Zhang, Lanjing; Joseph, Laurie B; Buckley, Brian; Kong, Bo; Guo, Grace L

Effects of therapeutically approved individual bile acids on the development of metabolic dysfunction-associated steatohepatitis a low bile acid mouse model

治疗性批准的单个胆汁酸对低胆汁酸小鼠模型中代谢功能障碍相关性脂肪性肝炎发展的影响

Taylor, Rulaiha; Basaly, Veronia; Kong, Bo; Yang, Ill; Brinker, Anita M; Capece, Gina; Bhattacharya, Anisha; Henry, Zakiyah R; Otersen, Katherine; Yang, Zhenning; Meadows, Vik; Mera, Stephanie; Joseph, Laurie B; Zhou, Peihong; Aleksunes, Lauren M; Roepke, Troy; Buckley, Brian; Guo, Grace L

Effects of ozone exposure on lung injury, inflammation, and oxidative stress in a murine model of nonpneumonic endotoxemia.

臭氧暴露对非肺炎内毒素血症小鼠模型肺损伤、炎症和氧化应激的影响

Radbel Jared, Meshanni Jaclynn A, Vayas Kinal N, Le-Hoang Oahn, Abramova Elena, Zhou Peihong, Joseph Laurie B, Laskin Jeffrey D, Gow Andrew J, Laskin Debra L

Skin Models Used to Define Mechanisms of Action of Sulfur Mustard

利用皮肤模型阐明芥子气的作用机制

Laskin, Jeffrey D; Ozkuyumcu, Kevin; Zhou, Peihong; Croutch, Claire R; Heck, Diane E; Laskin, Debra L; Joseph, Laurie B

Sulfur mustard corneal injury is associated with alterations in the epithelial basement membrane and stromal extracellular matrix

芥子气引起的角膜损伤与上皮基底膜和基质细胞外基质的改变有关。

Joseph, Laurie B; Gordon, Marion K; Zhou, Peihong; Hahn, Rita A; Lababidi, Hamdi; Croutch, Claire R; Sinko, Patrick J; Heck, Diane E; Laskin, Debra L; Laskin, Jeffrey D

Characterization of the rabbit conjunctiva: Effects of sulfur mustard

兔结膜的特征:芥子气的影响

Joseph, Laurie B; Gordon, Marion K; Kang, Jieun; Croutch, Claire R; Zhou, Peihong; Heck, Diane E; Laskin, Debra L; Laskin, Jeffrey D

Antioxidant Nanoparticles for Concerted Inhibition of α-Synuclein Fibrillization, and Attenuation of Microglial Intracellular Aggregation and Activation.

抗氧化纳米颗粒协同抑制α-突触核蛋白纤维化,减弱小胶质细胞内聚集和活化

Zhao Nanxia, Yang Xue, Calvelli Hannah R, Cao Yue, Francis Nicola L, Chmielowski Rebecca A, Joseph Laurie B, Pang Zhiping P, Uhrich Kathryn E, Baum Jean, Moghe Prabhas V

Derivatives of 1,2,4-triazole imines acting as dual iNOS and tumor cell growth inhibitors

1,2,4-三唑亚胺衍生物作为双重iNOS和肿瘤细胞生长抑制剂

Guillon, Christophe; Vetrano, Anna M; Saxena, Jaya; Hunter, Angela; Verderone, Geraldine; Finetti, Thomas M; Wisnoski, Jeffrey; DeMatteo, Peter W; Rapp, Robert D; Heindel, Ned D; Joseph, Laurie B; Heck, Diane E; Laskin, Jeffrey D