日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Blobulator: A Toolkit for Identification and Visual Exploration of Hydrophobic Modularity in Protein Sequences

Blobulator:用于识别和可视化探索蛋白质序列中疏水模块性的工具包

Pitman, Connor; Santiago-McRae, Ezry; Lohia, Ruchi; Lamb, Ryan; Bassi, Kaitlin; Riggs, Lindsey; Joseph, Thomas T; Hansen, Matthew E B; Brannigan, Grace

Activation dynamics of a water-soluble human mu-opioid receptor

水溶性人μ-阿片受体的激活动力学

Agyemang, Eugene; Van Wirt, Raegan; Walls, Calixte; Joseph, Thomas T; Tiruvadi-Krishnan, Sriram; Grothusen, John; Zhang, Qiu; Hicks, Alan; Leite, Wellington; Osti, Naresh C; Mamontov, Eugene; O'Neill, Hugh M; Liu, Renyu; Lamichhane, Rajan

Nitrous oxide activates layer 5 prefrontal neurons via SK2 channel inhibition for antidepressant effect.

一氧化二氮通过抑制 SK2 通道激活第 5 层前额叶神经元,从而产生抗抑郁作用

Cichon Joseph, Joseph Thomas T, Lu Xinguo, Wasilczuk Andrzej Z, Kelz Max B, Mennerick Steven J, Zorumski Charles F, Nagele Peter

The cryo-EM structure and physical basis for anesthetic inhibition of the THIK1 K2P channel

THIK1 K2P通道麻醉抑制的冷冻电镜结构和物理基础

Riel, Elena B; Bu, Weiming; Joseph, Thomas T; Khajoueinejad, Leila; Eckenhoff, Roderic G; Riegelhaupt, Paul M

Functionalization of 1,3-Diisopropylbenzene to Probe the Antagonism of Propofol Anesthesia

1,3-二异丙基苯的功能化及其对丙泊酚麻醉拮抗作用的研究

Hough, Morgan K; Leso, Ceilia R; Plasencia, Diana M; Joseph, Thomas T; White, E Railey

The blobulator: a toolkit for identification and visual exploration of hydrophobic modularity in protein sequences

疏水模块识别与可视化探索工具包:用于识别和可视化蛋白质序列疏水模块性的工具

Pitman, Connor; Santiago-McRae, Ezry; Lohia, Ruchi; Lamb, Ryan; Bassi, Kaitlin; Riggs, Lindsey; Joseph, Thomas T; Hansen, Matthew E B; Brannigan, Grace

Propofol binds and inhibits skeletal muscle ryanodine receptor 1

丙泊酚与骨骼肌兰尼碱受体1结合并抑制其活性。

Joseph, Thomas T; Bu, Weiming; Haji-Ghassemi, Omid; Chen, Yu S; Woll, Kellie; Allen, Paul D; Brannigan, Grace; van Petegem, Filip; Eckenhoff, Roderic G

Propofol directly binds and inhibits skeletal muscle ryanodine receptor 1 (RyR1)

丙泊酚直接结合并抑制骨骼肌兰尼碱受体 1 (RyR1)

Joseph, Thomas T; Bu, Weiming; Haji-Ghassemi, Omid; Chen, Yu Seby; Woll, Kellie; Allen, Paul D; Brannigan, Grace; van Petegem, Filip; Eckenhoff, Roderic G

Nitrous Oxide activates layer 5 prefrontal neurons via SK2 channel inhibition for antidepressant effect

一氧化二氮通过抑制SK2通道激活第5层前额叶神经元,从而产生抗抑郁作用。

Cichon, Joseph; Joseph, Thomas T; Lu, Xinguo; Wasilczuk, Andrzej Z; Kelz, Max B; Mennerick, Steven J; Zorumski, Charles F; Nagele, Peter

alchemlyb: the simple alchemistry library

alchemlyb:简易炼金术库

Wu, Zhiyi; Dotson, David L; Alibay, Irfan; Allen, Bryce K; Barhaghi, Mohammad Soroush; Hénin, Jérôme; Joseph, Thomas T; Kenney, Ian M; Lee, Hyungro; Li, Haoxi; Lim, Victoria; Liu, Shuai; Marson, Domenico; Merz, Pascal T; Schlaich, Alexander; Mobley, David; Shirts, Michael R; Beckstein, Oliver