日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

EGFRvIII Confers Sensitivity to Saracatinib in a STAT5-Dependent Manner in Glioblastoma

EGFRvIII 以 STAT5 依赖的方式赋予胶质母细胞瘤对萨拉替尼的敏感性

Mylan R Blomquist, Ryan Eghlimi, Angad Beniwal, Dustin Grief, David G Nascari, Landon Inge, Christopher P Sereduk, Serdar Tuncali, Alison Roos, Hannah Inforzato, Ritin Sharma, Patrick Pirrotte, Shwetal Mehta, Shannon P Fortin Ensign, Joseph C Loftus, Nhan L Tran

Leukemia-Associated Rho Guanine Nucleotide Exchange Factor and Ras Homolog Family Member C Play a Role in Glioblastoma Cell Invasion and Resistance

白血病相关 Rho 鸟嘌呤核苷酸交换因子和 Ras 同源物家族成员 C 在胶质母细胞瘤细胞侵袭和耐药中发挥作用

Zonghui Ding, Zhiwan Dong, Yuping Yang, Shannon P Fortin Ensign, Hemragul Sabit, Mitsutoshi Nakada, Rosamaria Ruggieri, Jean M Kloss, Marc Symons, Nhan L Tran, Joseph C Loftus

TROY signals through JAK1-STAT3 to promote glioblastoma cell migration and resistance

TROY通过JAK1-STAT3发出信号促进胶质母细胞瘤细胞迁移和抗性

Zonghui Ding, Jean M Kloss, Serdar Tuncali, Nhan L Tran, Joseph C Loftus

Inhibition of phosphatidylinositol 3-kinase by PX-866 suppresses temozolomide-induced autophagy and promotes apoptosis in glioblastoma cells

PX-866 抑制磷脂酰肌醇 3-激酶可抑制替莫唑胺诱导的自噬并促进胶质母细胞瘤细胞凋亡

Bryan G Harder, Sen Peng, Christopher P Sereduk, Andrej M Sodoma, Gaspar J Kitange, Joseph C Loftus, Jann N Sarkaria, Nhan L Tran

EGFRvIII-Stat5 Signaling Enhances Glioblastoma Cell Migration and Survival

EGFRvIII-Stat5 信号增强胶质母细胞瘤细胞迁移和存活

Alison Roos, Harshil D Dhruv, Sen Peng, Landon J Inge, Serdar Tuncali, Michael Pineda, Nghia Millard, Zachary Mayo, Jennifer M Eschbacher, Joseph C Loftus, Jeffrey A Winkles, Nhan L Tran

A Novel Signaling Complex between TROY and EGFR Mediates Glioblastoma Cell Invasion

TROY 和 EGFR 之间的新型信号复合物介导胶质母细胞瘤细胞侵袭

Zonghui Ding, Alison Roos, Jean Kloss, Harshil Dhruv, Sen Peng, Patrick Pirrotte, Jennifer M Eschbacher, Nhan L Tran, Joseph C Loftus

PDZ-RhoGEF Is a Signaling Effector for TROY-Induced Glioblastoma Cell Invasion and Survival

PDZ-RhoGEF 是 TROY 诱导的胶质母细胞瘤细胞侵袭和存活的信号效应子

Zonghui Ding, Harshil Dhruv, Aneta Kwiatkowska-Piwowarczyk, Rosamaria Ruggieri, Jean Kloss, Marc Symons, Patrick Pirrotte, Jennifer M Eschbacher, Nhan L Tran, Joseph C Loftus

Propentofylline inhibits glioblastoma cell invasion and survival by targeting the TROY signaling pathway

丙戊茶碱通过靶向TROY信号通路抑制胶质母细胞瘤细胞侵袭和存活

Harshil D Dhruv, Alison Roos, Patrick J Tomboc, Serdar Tuncali, Ashley Chavez, Ian Mathews, Michael E Berens, Joseph C Loftus, Nhan L Tran

Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma

靶向 aPKC 可抑制胶质母细胞瘤中 EGFR 和促炎细胞因子 TNFα 的致癌信号传导

Yael Kusne #, Eugenio A Carrera-Silva #, Anthony S Perry, Elisabeth J Rushing, Edward K Mandell, Justin D Dietrich, Andrea E Errasti, Daniel Gibbs, Michael E Berens, Joseph C Loftus, Christopher Hulme, Weiwei Yang, Zhimin Lu, Kenneth Aldape, Nader Sanai, Carla V Rothlin, Sourav Ghosh

Structural basis and targeting of the interaction between fibroblast growth factor-inducible 14 and tumor necrosis factor-like weak inducer of apoptosis

成纤维细胞生长因子诱导因子14与肿瘤坏死因子样弱凋亡诱导因子相互作用的结构基础和靶向性

Harshil Dhruv, Joseph C Loftus, Pooja Narang, Joachim L Petit, Maureen Fameree, Julien Burton, Giresse Tchegho, Donald Chow, Holly Yin, Yousef Al-Abed, Michael E Berens, Nhan L Tran, Nathalie Meurice